| Sirs of the lowest rank | 23 |
| Sirs' counterparts | 22 |
| Sis, boom, bah's kin | 24 |
| Sisal and Bombay, e.g. | 22 |
| Sisal processing plant | 22 |
| Siskel reaction, sometimes | 26 |
| Siskel's TV partner | 23 |
| Sisqo's group ___ Hill | 26 |
| Sissy of "Carrie" | 27 |
| Sissy Spacek title role | 23 |
| Sissy who's not a sissy | 27 |
| Sissy's biopic role | 23 |
| Sister and wife of Hyperion | 27 |
| Sister and wife of Osiris | 25 |
| Sister and wife of Zeus | 23 |
| Sister Bertrille, e.g. | 22 |
| Sister brand of Armor All | 25 |
| Sister brand of Beneful | 23 |
| Sister brand of CorningWare | 27 |
| Sister brand of Doritos | 23 |
| Sister brand of Snapple | 23 |
| Sister brand of Swatch | 22 |
| Sister chain of Hardee's | 28 |
| Sister channel of Chiller | 25 |
| Sister channel of Cinemax | 25 |
| Sister channel of Starz | 23 |
| Sister city of El Paso | 22 |
| Sister city of St. Petersburg | 29 |
| Sister co. of Applebee's | 28 |
| Sister company of Zipcar | 24 |
| Sister Eileen's state | 25 |
| Sister goddess of Calliope | 26 |
| Sister in "Sisters" | 29 |
| Sister in a Chekhov play | 24 |
| Sister in a film title | 22 |
| Sister in an Eastwood film | 26 |
| Sister island of Nevis | 22 |
| Sister Kate's dance | 23 |
| Sister magazine of Jet | 22 |
| Sister magazine of Maxim | 24 |
| Sister of a padre, e.g. | 23 |
| Sister of Amy, Beth and Jo | 26 |
| Sister of Amy, Jo and Meg | 25 |
| Sister of Amy, Meg and Jo | 25 |
| Sister of Anne and Charlotte | 28 |
| Sister of Bart and Maggie | 25 |
| Sister of Bart Simpson | 22 |
| Sister of Bert Bobbsey | 22 |
| Sister of Boris Godunov | 23 |
| Sister of Castor and Pollux | 27 |
| Sister of Charles and Andrew | 28 |
| Sister of Charlotte and Emily | 29 |
| Sister of Clio and Calliope | 27 |
| Sister of Emily and Charlotte | 29 |
| Sister of Erato or Clio | 23 |
| Sister of Eva and Magda | 23 |
| Sister of Eva and Zsa Zsa | 25 |
| Sister of Fred Astaire | 22 |
| Sister of Helios and Selene | 27 |
| Sister of Hestia and Hades | 26 |
| Sister of Jack and Bobby | 24 |
| Sister of Janet and Michael | 27 |
| Sister of Jo, Amy and Beth | 26 |
| Sister of Jo, Amy, and Beth | 27 |
| Sister of Jo, in literature | 27 |
| Sister of John and Lionel | 25 |
| Sister of John-Boy Walton | 25 |
| Sister of Khloe and Kourtney | 28 |
| Sister of Luke, in sci-fi | 25 |
| Sister of Magda and Eva | 23 |
| Sister of Maggie and Bart | 25 |
| Sister of Marge Simpson | 23 |
| Sister of Masha and Irina | 25 |
| Sister of Masha and Olga | 24 |
| Sister of Meg and Beth | 22 |
| Sister of Meg, Jo and Amy | 25 |
| Sister of Michael and Janet | 27 |
| Sister of Moses and Aaron | 25 |
| Sister of Notre Dame de ___ | 27 |
| Sister of Olga and Masha | 24 |
| Sister of Patty and Marge | 25 |
| Sister of Peter Rabbit | 22 |
| Sister of Phoebe, in myth | 25 |
| Sister of Prince Charles | 24 |
| Sister of Sol and Luna | 22 |
| Sister of Stheno and Euryale | 28 |
| Sister of Zsa Zsa and Eva | 25 |
| Sister of Zsa Zsa and Magda | 27 |
| Sister or story starter | 23 |
| Sister port of Algiers | 22 |
| Sister record co. of Virgin | 27 |
| Sister station of Flix | 22 |
| Sister store of Off 5th | 23 |
| Sister store of Old Navy | 24 |
| Sister to Patty and Selma | 25 |
| Sister wearing a habit | 22 |
| Sister's daughter, e.g. | 27 |
| Sister's daughters | 22 |
| Sister's study: Abbr. | 25 |
| Sister's title, perhaps | 27 |