| Island that's home to a state capital | 41 |
| Island that's home to orangutans | 36 |
| Island that's now called Sri Lanka | 38 |
| Island that's second to Java in population | 46 |
| Island that's the burial place of Macbeth | 45 |
| Island thatÂ's not all island | 37 |
| Island to which Gauguin went after leaving Europe | 49 |
| Island tourist destination in Indonesia | 39 |
| Island town whose sign boasts a giant potato | 44 |
| Island united politically with Trinidad | 39 |
| Island vacationer's greeting | 32 |
| Island visited by Captain Cook in 1778 | 38 |
| Island visited by Columbus in 1492 | 34 |
| Island visited by Hudson in 1609 | 32 |
| Island visited by Magellan, 1521 | 32 |
| Island visited by many immigrants | 33 |
| Island visited by the Hawaii Superferry | 39 |
| Island visited by the HMS Bounty | 32 |
| Island wear purchased in the Atlantic? | 38 |
| Island wear purchased in the Caribbean? | 39 |
| Island wear purchased in the Pacific? | 37 |
| Island wear purchased in the Tyrrhenian? | 40 |
| Island wear that spawns lame sex jokes | 38 |
| Island where "Jaws" took place | 40 |
| Island where "Jurassic Park" was filmed | 49 |
| Island where "Lost" is filmed | 39 |
| Island where "Lost" was filmed | 40 |
| Island where a noted Greek statue was found | 43 |
| Island where Bill and Melinda Gates were wed | 44 |
| Island where Danno booked 'em | 33 |
| Island where Father Damien cared for lepers | 43 |
| Island where Homer is allegedly buried | 38 |
| Island where Homer is buried, by tradition | 42 |
| Island where Homer is supposedly buried | 39 |
| Island where Homer was reputedly born | 37 |
| Island where Icarus was imprisoned | 34 |
| Island where karate was developed | 33 |
| Island where Napoleon spent 42 weeks in exile | 45 |
| Island where Napoleon was exiled (and died) | 43 |
| Island where Rafael Nadal was born | 34 |
| Island where Robert Louis Stevenson died | 40 |
| Island where Sundanese and Madurese are spoken | 46 |
| Island where the British first settled America | 46 |
| Island where the daiquiri was invented | 38 |
| Island where the Labyrinth was located | 38 |
| Island where the Pro Bowl is played | 35 |
| Island where Virginia Dare was born | 35 |
| Island whose capital is Denpasar | 32 |
| Island whose capital is Gustavia, familiarly | 44 |
| Island whose capital is Hagåtña | 37 |
| Island whose capital is Hamilton | 32 |
| Island whose chief port is Mahón | 35 |
| Island whose highest peak is Mont Orohena | 41 |
| Island whose highest peak is Orohena | 36 |
| Island whose largest town is Scarborough | 40 |
| Island with a 13th-century cathedral | 36 |
| Island with a statue of Duke Kahanamoku | 39 |
| Island with a view of the Golden Gate | 37 |
| Island with an area larger than Texas | 37 |
| Island with large oil refineries | 32 |
| Island with many Obama impersonators | 36 |
| Island with the capital city Basseterre | 39 |
| Island with the volcano Mt. Liamuiga | 36 |
| Island-dotted lake of Northern Ireland | 38 |
| Islands explored by Magellan in 1521 | 36 |
| Islands in the Straits of Florida | 33 |
| Islands known for giant tortoises | 33 |
| Islands of which Inishmore is the largest | 41 |
| Islands to which canaries are native | 36 |
| Islands' body part (with "The") | 45 |
| Isle for which a clothing style is named | 40 |
| Isle of exile to which many modern Romans escape | 48 |
| Isle of Man's northern point | 32 |
| Isle of ___ (part of Cambridgeshire, England) | 45 |
| Isle serenaded in "South Pacific" | 43 |
| Isle where Homer is buried, supposedly | 38 |
| Isle where several Scottish kings are buried | 44 |
| Isles of __: Gulf of Maine locale | 33 |
| Isley Brothers hit "___ Lady" | 39 |
| Isn't clear in speech, maybe | 32 |
| Isn't completely honest with | 32 |
| Isn't content with the status quo, say | 42 |
| Isn't likely to win any culinary awards | 43 |
| Isn't perfectly perpendicular | 33 |
| Isn't respectful to, in a way | 33 |
| Isn't straight in the middle | 32 |
| Isn't too tight or too loose | 32 |
| Isn't totally out of the race | 33 |
| Isolated (with ''off'') | 39 |
| Isolated flare up disrupted by expedition (11) | 46 |
| Isolated hill surrounded by lava | 32 |
| Isolated, (with "off") | 32 |
| Isolates, as one from among many | 32 |
| Isolationist in the Senate: 1925–45 | 42 |
| ISP featuring CBS Radio stations | 32 |
| ISP that debuted with Windows 95 | 32 |
| ISP that used to mail free trial discs | 38 |
| ISP with a circle-in-a-triangle logo | 36 |
| Israel and India are both part of it | 36 |
| Israel Kamakawiwo'ole's instrument | 42 |