| Big accounts | 12 |
| Big acronym in energy | 21 |
| Big ad guy? | 11 |
| Big admirer | 11 |
| Big ados | 8 |
| Big advances | 12 |
| Big advantages in sports | 24 |
| Big advertiser at Indy | 22 |
| Big affair | 10 |
| Big affairs | 11 |
| Big African antelope | 20 |
| Big African beast | 17 |
| Big African critter | 19 |
| Big airline until 2001 | 22 |
| Big airplane engine | 19 |
| Big airport | 11 |
| Big Akron employer | 18 |
| Big amount | 10 |
| Big and bright fish | 19 |
| Big and burly | 13 |
| Big and burly, maybe | 20 |
| Big and clumsy | 14 |
| Big and clumsy types | 20 |
| Big and cumbersome | 18 |
| Big and drafty | 14 |
| Big and fast jet | 16 |
| Big and Gentle | 14 |
| Big and little | 14 |
| Big and little digit | 20 |
| Big and muscular | 16 |
| Big and red, say | 16 |
| Big and rugged | 14 |
| Big and small, e.g.: Abbr. | 26 |
| Big and strong | 14 |
| Big animal | 10 |
| Big animal in the jungle | 24 |
| Big announcement from a music group | 35 |
| Big annual beauty contest | 25 |
| Big annual moment for E! | 24 |
| Big antelope | 12 |
| Big apartment | 13 |
| Big apartments | 14 |
| Big ape | 7 |
| Big ape that sings well? | 24 |
| Big apes | 8 |
| Big apes, for short | 19 |
| Big appetites | 13 |
| Big Apple | 9 |
| Big Apple abbr. | 15 |
| Big Apple addr. | 15 |
| Big Apple address | 17 |
| Big Apple address letters | 25 |
| Big Apple address, briefly | 26 |
| Big Apple advertising center | 28 |
| Big Apple airport abbr. | 23 |
| Big Apple airport code | 22 |
| Big Apple archbishop | 20 |
| Big Apple area | 14 |
| Big Apple area (with "the") | 37 |
| Big Apple area near TriBeCa | 27 |
| Big Apple area north of Madison Square Garden | 45 |
| Big Apple art museum | 20 |
| Big Apple artery, with "the" | 38 |
| Big Apple attraction (with "The") | 43 |
| Big Apple attraction, with "the" | 42 |
| Big Apple ave. | 14 |
| Big Apple award | 15 |
| Big Apple awards | 16 |
| Big Apple ballpark | 18 |
| Big Apple baseball mascot | 25 |
| Big Apple baseball name | 23 |
| Big Apple baseball stadium | 26 |
| Big Apple baseball team | 23 |
| Big Apple baseball venue | 24 |
| Big Apple baseballer | 20 |
| Big Apple baseballers | 21 |
| Big Apple bigwig | 16 |
| Big Apple borough | 17 |
| Big Apple bridge, informally | 28 |
| Big Apple cab words | 19 |
| Big Apple campus at Washington Sq. | 34 |
| Big Apple cardinal | 18 |
| Big Apple cathedral, familiarly | 31 |
| Big Apple college inits. | 24 |
| Big Apple cop who's looking to bust Popeye? | 47 |
| Big Apple cops | 14 |
| Big Apple cops' org. | 24 |
| Big Apple couple | 16 |
| Big Apple cultural attraction, with "the" | 51 |
| Big Apple daily, briefly | 24 |
| Big Apple daily, in brief | 25 |
| Big Apple daily: Abbr. | 22 |
| Big Apple dairy product? | 24 |
| Big Apple dweller | 17 |
| Big Apple eatery | 16 |
| Big Apple educ. inits. | 22 |
| Big Apple educ. institution | 27 |
| Big Apple enforcement gp. | 25 |
| Big Apple enforcement org. | 26 |
| Big Apple enforcers (abbr.) | 27 |