| Opposite of precipitous | 23 |
| Opposite of protruding | 22 |
| Opposite of pulls away | 22 |
| Opposite of reggae feeling? | 27 |
| Opposite of Rocky Rd.? | 22 |
| Opposite of safe, sometimes | 27 |
| Opposite of sang-froid | 22 |
| Opposite of schadenfreude | 25 |
| Opposite of send packing | 24 |
| Opposite of separateness | 24 |
| Opposite of sheer genius | 24 |
| Opposite of simplicity | 22 |
| Opposite of six, on a die | 25 |
| Opposite of sluggishness | 24 |
| Opposite of socially smooth | 27 |
| Opposite of spring, tide-wise | 29 |
| Opposite of spring, tidewise | 28 |
| Opposite of strengthen | 22 |
| Opposite of sur, in Spain | 25 |
| Opposite of taboo, in Hilo | 26 |
| Opposite of the clue above | 26 |
| Opposite of the psyche | 22 |
| Opposite of the seven seas? | 27 |
| Opposite of throw away | 22 |
| Opposite of transparent | 23 |
| Opposite of unter, in German | 28 |
| Opposite of vert., on old TVs | 29 |
| Opposite of vertical: Abbr. | 27 |
| Opposite of wasted away | 23 |
| Opposite of wasting away | 24 |
| Opposite of well-dressed? | 25 |
| Opposite of whole, milkwise | 27 |
| Opposite of yours, in Tours | 27 |
| Opposite sides of a fight | 25 |
| Opposite-creating prefix | 24 |
| Opposite-of-expected outcomes | 29 |
| Opposites of debits: Abbr. | 26 |
| Opposites of opposites: Abbr. | 29 |
| Opposites of thinkers? | 22 |
| Opposition party member | 23 |
| Opposition to A.C. flow | 23 |
| Opposition to use of force | 26 |
| Oppressed by people in power | 28 |
| Oppressed by the heat? | 22 |
| Oprah and Dr. Phil, e.g. | 24 |
| Oprah has more than one | 23 |
| Oprah Winfrey forerunner Phil | 29 |
| Oprah Winfrey's company | 27 |
| Oprah's best friend | 23 |
| Oprah's best-selling cook | 29 |
| Oprah's doctor friend | 25 |
| Oprah's Life Lift, e.g. | 27 |
| Oprah's production studio | 29 |
| Oprah's TV network | 22 |
| Opt for a suit and tie | 22 |
| Opt for the gold watch? | 23 |
| Opt not to charge, perhaps | 26 |
| Opt not to get carry-out | 24 |
| Opt out of the local union? | 27 |
| Opted for a new hair color | 26 |
| Opted for paper over plastic? | 29 |
| Optic activity during sleep | 27 |
| Optic membrane: Comb. form | 26 |
| Optical illusion artist | 23 |
| Optical illusion illustrator | 28 |
| Optical products pioneer | 24 |
| Optical-instrument part | 23 |
| Optician's concern | 22 |
| Optician's creation | 23 |
| Optician's display | 22 |
| Optician's product | 22 |
| Optician's products | 23 |
| Optician's selection | 24 |
| Optician's selections | 25 |
| Opticians' products | 23 |
| Optics device used by Newton | 28 |
| Optimism; cheerfulness | 22 |
| Optimist's assertion | 24 |
| Optimist's attribute | 24 |
| Optimist's coloring | 23 |
| Optimist's comment | 22 |
| Optimist's feature | 22 |
| Optimist's feeling | 22 |
| Optimist's hallmark | 23 |
| Optimist's pronouncement | 28 |
| Optimist's quality | 22 |
| Optimist's statement | 24 |
| Optimist's view of time | 27 |
| Optimist's worldview | 24 |
| Optimist: "My ___" | 28 |
| Optimistic about a stock | 24 |
| Optimistic and then some | 24 |
| Optimistic expectations | 23 |
| Optimistic Miller play? | 23 |
| Optimistic theater audience? | 28 |
| Optimistic, as an outlook | 25 |
| Optimists keep them alive | 25 |
| Optimists' activity | 23 |
| Optimists' storage boxes | 28 |
| Opting not to strike out? | 25 |