| ''SNL'' comic Radner | 36 |
| ''SNL'' alumna Dunn | 35 |
| ''Snicker'' attachment | 38 |
| ''Snakes ___ Plane'' | 36 |
| ''Smooth Operator'' singer | 42 |
| ''Smooth Operator'' chanteuse | 45 |
| ''Smoking ___?'' | 32 |
| ''Smoking or ___?'' | 35 |
| ''Smoking or __?'' | 34 |
| ''Smoke ___ in Your Eyes'' | 42 |
| ''Smiling'' sled dogs | 37 |
| ''Smart Television'' subject | 44 |
| ''Smallville'' teen | 35 |
| ''Smallville'' network | 38 |
| ''Smallville'' girl | 35 |
| ''Smallville'' crowd, e.g. | 42 |
| ''Slowly ___ the lea'' | 38 |
| ''Slippery when ___'' | 37 |
| ''Sleeping Beauty'' princess | 44 |
| ''Sleep'' word starter | 38 |
| ''Slammin' Sammy'' | 38 |
| ''SKNX-X-X!'' sayer | 35 |
| ''Skip the details'' | 36 |
| ''Skin'' word form | 34 |
| ''Skin'' starter | 32 |
| ''Skeletal'' prefix | 35 |
| ''Six ___, half a dozen ...'' | 45 |
| ''Six __, and half . . .'' | 42 |
| ''Sister Carrie'' author | 40 |
| ''Sister Act'' sister | 37 |
| ''Singin' in the Rain'' star | 48 |
| ''Sincerely,'' and others | 41 |
| ''Sincerely'' and others | 40 |
| ''Simpsons'' toon cat | 37 |
| ''Simpsons'' storekeeper | 40 |
| ''Simpsons'' sister | 35 |
| ''Simpsons'' shout | 34 |
| ''Simpsons'' outburst | 37 |
| ''Simpsons'' network | 36 |
| ''Simpsons'' grandpa | 36 |
| ''Simpsons'' daughter | 37 |
| ''Simpsons'' bus driver | 39 |
| ''Simpsons'' bartender | 38 |
| ''Simpsons'' bar owner | 38 |
| ''Silkwood'' star | 33 |
| ''Silent'' president | 36 |
| ''Silent Night,'' for one | 41 |
| ''Silent Night,'' e.g. | 38 |
| ''Silent Movie'' actress | 40 |
| ''Silas Marner'' writer | 39 |
| ''Silas Marner'' character | 42 |
| ''Silas Marner'' author | 39 |
| ''Siegfried'' solo | 34 |
| ''Sideways'' subject | 36 |
| ''Siddhartha'' writer | 37 |
| ''Siddhartha'' author | 37 |
| ''Si, Mi Chiamano Mimi,'' e.g. | 46 |
| ''SI'' or ''GQ'' | 48 |
| ''Showboat'' author Ferber | 42 |
| ''Show some mercy!'' | 36 |
| ''Show me'' types | 33 |
| ''Show Boat'' novelist Ferber | 45 |
| ''Show Boat'' composer Jerome | 45 |
| ''Show Boat'' composer | 38 |
| ''Show Boat'' author Ferber | 43 |
| ''Should that be the case'' | 43 |
| ''Short'' weight | 32 |
| ''Short and stout'' vessel | 42 |
| ''Shopgirl'' author Martin | 42 |
| ''Shop ___ you drop'' | 37 |
| ''Shoo!'' on the farm? | 38 |
| ''Shogun'' setting | 34 |
| ''Shogun'' apparel | 34 |
| ''Ship of Fools'' author | 40 |
| ''Shine'' Oscar winner | 38 |
| ''Shepherd Moons'' Grammy winner | 48 |
| ''She Walks in Beauty'' poet | 44 |
| ''She Loves You'' word | 38 |
| ''She loves me'' unit | 37 |
| ''She loves me not'' flowers | 44 |
| ''She Done ___ Wrong'' | 38 |
| ''Share the secret!'' | 37 |
| ''Shane'' star Ladd | 35 |
| ''Shame on you!'' sound | 39 |
| ''Shame on you!'' | 33 |
| ''Shallow ___'' (2001 film) | 43 |
| ''Shall we?'' response | 38 |
| ''Shall we?'' reply | 35 |
| ''Shakespeare in Love'' weapons | 47 |
| ''Shakespeare in Love'' star | 44 |
| ''Shake!'' offering | 35 |
| ''Shaft'' singer Hayes | 38 |
| ''Shaft'' composer Hayes | 40 |
| ''Shaft'' composer | 34 |
| ''Shadowland'' singer k.d. | 42 |
| ''Shadowland'' singer | 37 |
| ''Shade'' starter | 33 |
| ''Sgt. Pepper'' track | 37 |
| ''Seward's Folly'' | 38 |
| ''Severn Suite'' composer | 41 |