| McGuffey's offering | 23 |
| McGuire-McHugh twosome | 22 |
| McGwire broke his record | 24 |
| McGwire or Maddux, for short | 28 |
| McGwire's 1998 rival | 24 |
| McGwire's rival in 1998 | 27 |
| McHenry and Raleigh, e.g. | 25 |
| McHenry and Sumter: Abbr. | 25 |
| MCI competitor, way back when | 29 |
| McIlhenny Company sauce | 23 |
| McIntoshes, for example | 23 |
| McKellen of 'Scandal' | 29 |
| McKellen of 'X-Men' | 27 |
| McKellen of "X-Men" | 29 |
| McKellen of "X2" | 26 |
| McKellen who played Gandalf | 27 |
| McKenzie, Brackman TV series | 28 |
| McKern of "Help!" | 27 |
| McKinley and Hood: Abbr. | 24 |
| McKinley and others: Abbr. | 26 |
| McKinley or Washington | 22 |
| McKinley policy for China | 25 |
| McKinley's birthplace | 25 |
| McKinley's first lady | 25 |
| McKinley's home state | 25 |
| McKinley's sponsor | 22 |
| McKinley's wife et al. | 26 |
| McKinsey employee, perhaps | 26 |
| McLachlan hit of the 1990s | 26 |
| McLean's sitcom co-star | 27 |
| McMahon Act creation: Abbr. | 27 |
| McMahon's drawn-out word | 28 |
| McMahon's intro word | 24 |
| McMahon's schooling? | 24 |
| McMansion's lot, maybe | 26 |
| McMansion's storage | 23 |
| McMansion, in other words | 25 |
| MCMLVII and MCMLVIII, e.g. | 26 |
| McMurdo Station location | 24 |
| McMurry University site | 23 |
| McNally's map partner | 25 |
| McNally's mapmaking mate | 28 |
| McNamara's, for one | 23 |
| McPherson of evangelism | 23 |
| McPherson Pulitzer-winner | 25 |
| McRee's predecessor | 23 |
| McShane of Lovejoy | 22 |
| McShane of 'Deadwood' | 29 |
| McSorley's Bar painter | 29 |
| McSorley's offering | 23 |
| McSorley's Old ___ House | 28 |
| McSorley's product | 22 |
| McSorley's serving | 22 |
| MD who treats sinusitis | 23 |
| MD's "Pronto!" | 28 |
| MD's calendar listing | 25 |
| MD's employer, maybe | 24 |
| MD's skull session? | 23 |
| MD's wall hangings | 22 |
| Md. institution since 1845 | 26 |
| Md. town near Baltimore | 23 |
| Md.'s former Gretna Green | 29 |
| Md.'s largest city | 22 |
| Md.'s ___ Proving Ground | 28 |
| MDs for otitis sufferers | 24 |
| MDs for sinus sufferers | 23 |
| MDs who deliver babies | 22 |
| MDs who don't specialize | 28 |
| MDs who treat pushers? | 22 |
| MDW neighbor in Chicago | 23 |
| Me non ___ (she loves me not) | 29 |
| Me ___ (You love me): Lat. | 26 |
| Me, it's often said | 23 |
| Me, some sometimes say | 22 |
| Me-generation concerns | 22 |
| Me-time place, perhaps | 22 |
| Me-tooer's response | 23 |
| Me-___ (coattails policy) | 25 |
| Me. city SW of Portland | 23 |
| Me. motorist's menace | 25 |
| Me. retailer, initially | 23 |
| Me. river + Okla. city | 22 |
| Mead's publishing partner | 29 |
| Meade vs. Lee, July 1863 | 24 |
| Meadow soprano, perhaps? | 24 |
| Meadowland measurement | 22 |
| Meadowlands and Kemper | 22 |
| Meadowlands cascade, at times | 29 |
| Meadowlands competitor | 22 |
| Meadowlands competitors | 23 |
| Meadowlands contestant | 22 |
| Meadowlands hockey player | 25 |
| Meadowlands Stadium team | 24 |
| Meadowlark Lemon, e.g. | 22 |
| Meadowlark Lemon, once | 22 |
| Meadowlark's cousin | 23 |
| Meadowlark's relative | 25 |
| Meadows from Wu Chang, China | 28 |
| Meager cream cheese portion? | 28 |
| Meager fare for Oliver Twist | 28 |