| Two-liter bottle contents, sometimes | 36 |
| Two-Oscar actor who loved crosswords | 36 |
| Two-part lake connected by the Strait of Tiquina | 48 |
| Two-person pencil-and-paper game | 32 |
| Two-person starter home of note? | 32 |
| Two-piece suit that won't keep you warm | 43 |
| Two-player logic game with colored pegs | 39 |
| Two-reeler about baseballer Darryl? | 35 |
| Two-seaters or four-seaters, e.g.? | 34 |
| Two-sevenths of the territories on a Risk board | 47 |
| Two-term presidents' tenures, e.g. | 38 |
| Two-term presidents' terms, e.g. | 36 |
| Two-thirds of a double-play combo | 33 |
| Two-thirds of a Three Tenors selection | 38 |
| Two-thirds of the Belmont Stakes | 32 |
| Two-time '70s Stanley Cup champs | 36 |
| Two-time '80s-'90s Senate majority leader | 49 |
| Two-time "MASH" Emmy winner | 37 |
| Two-time 1500-meter Olympic gold medalist | 41 |
| Two-time 1980s skating gold medalist | 36 |
| Two-time 1980s skating gold medalist Katarina | 45 |
| Two-time 1990s A.L. batting champ Edgar | 39 |
| Two-time A.L. home run champ Tony | 33 |
| Two-time A.L. homer leader Thomas | 33 |
| Two-time achievement for the Chicago Bulls | 42 |
| Two-time All-Star power forward Carlos | 38 |
| Two-time Australian Open champ Williams | 39 |
| Two-time baseball All-Star Sandoval | 35 |
| Two-time belligerent against the British Empire | 47 |
| Two-time Best Actress Oscar winner Jackson | 42 |
| Two-time Best Actress winner Rainer | 35 |
| Two-time Best Adapted Screenplay Oscar winner | 45 |
| Two-time Best Director Oscar winner Lee | 39 |
| Two-time Best Rock Album Grammy winner | 38 |
| Two-time Best Situation Comedy Emmy winner | 42 |
| Two-time Best Spoken Word Album Grammy winner | 45 |
| Two-time Conn Smythe Trophy winner | 34 |
| Two-time costar with Eddie Murphy | 33 |
| Two-time Cy Young Award winner Halladay | 39 |
| Two-time Cy Young winner Lincecum | 33 |
| Two-time Cy Young winner Saberhagen | 35 |
| Two-time Emmy winner as best actor in a comedy | 46 |
| Two-time Emmy winner for "30 Rock" | 44 |
| Two-time Fiction Pulitzer winner | 32 |
| Two-time FIFA Ballon d'Or winner | 36 |
| Two-time FIFA World Player of the Year Lionel | 45 |
| Two-time football Pro Bowler Leon | 33 |
| Two-time foreign minister of the U.S.S.R. | 41 |
| Two-time Gold Glove second baseman Pokey | 40 |
| Two-time gold medal skier of the 1998 Olympics | 46 |
| Two-time Golden Raspberry nominee Jessica | 41 |
| Two-time Grammy Award-winning pianist Peter | 43 |
| Two-time Grammy winner __ Lee Jones | 35 |
| Two-time Grammy-winning pianist Peter | 37 |
| Two-time green jacket wearer Bernhard | 37 |
| Two-time Haitian president Préval | 36 |
| Two-time Hart Trophy winner, familiarly | 39 |
| Two-time heavyweight champ Patterson | 36 |
| Two-time host of the Summer Olympics | 36 |
| Two-time Hugo Award winner Gaiman | 33 |
| Two-time Indian Prime Minister Gandhi | 37 |
| Two-time Indy 500 champ Luyendyk | 32 |
| Two-time Indy 500 winner Luyendyk | 33 |
| Two-time Indy 500 winner ___ Luyendyk | 37 |
| Two-time Italian prime minister Aldo | 36 |
| Two-time Italian prime minister Giuliano | 40 |
| Two-time Italian prime minister Moro | 36 |
| Two-time Jack Nicklaus Trophy winner Jay | 40 |
| Two-time L.P.G.A. champ born in Korea | 37 |
| Two-time L.P.G.A. Championship winner Laura | 43 |
| Two-time loser to Graf at the US Open | 37 |
| Two-time losing Republican presidential candidate | 49 |
| Two-time Masters winner Bernhard | 32 |
| Two-time N.B.A. All-Star Robinson | 33 |
| Two-time N.L. batting champ Lefty | 33 |
| Two-time N.L. batting champ Richie | 34 |
| Two-time N.L. M.V.P., 1954 and 1965 | 35 |
| Two-time NAACP Image award-winning actor | 40 |
| Two-time NASCAR champion Jarrett | 32 |
| Two-time National League batting champ Lefty | 44 |
| Two-time National League MVP Murphy | 35 |
| Two-time national ticket candidate | 34 |
| Two-time NBA all-star Vandeweghe | 32 |
| Two-time Newbery winner ___ Lowry | 33 |
| Two-time Nicaraguan president Chamorro | 38 |
| Two-time Olivier Award winner Jacobi | 36 |
| Two-time Olympic ice-skating medalist Brian | 43 |
| Two-time Olympic pairs skating champ Ekaterina | 46 |
| Two-time Olympic skating medalist Michelle | 42 |
| Two-time Olympic slalom medalist Phil | 37 |
| Two-time Olympics gold-metal skater | 35 |
| Two-time Oscar nominee as Henry II | 34 |
| Two-time Oscar nominee for portraying Henry II | 46 |
| Two-time Oscar nominee J. Carrol ___ | 36 |
| Two-time Oscar winner for Best Adapted Screenplay | 49 |
| Two-time Oscar winner in the tub? | 33 |
| Two-time Oscar-winning cinematographer Nykvist | 46 |
| Two-time Oscar-winning director Frank ___ | 41 |
| Two-time Oscar-winning director Lee | 35 |
| Two-time Oscar-winning screenwriter | 35 |