| UNICEF's first celebrity ambassador Danny | 45 |
| UNICEF's first celebrity ambassador | 39 |
| Unholy combinations of circumstances | 36 |
| Unhelpful spelling clarification #1 | 35 |
| Unhelpful opening to a phone conversation | 41 |
| Unhelpful noughts-and-crosses line | 34 |
| Unhelpful implements in janitors' closets | 45 |
| Unhealthy stuff that's cured | 32 |
| Unhealthful dietary intake, briefly | 35 |
| Unharmed accident victim's response | 39 |
| Unhappy Pearl Jam "Lost Dogs" track? | 46 |
| Unhappy outcome of a Mozart opus? | 33 |
| Unhappy author's complaint to an editor? | 44 |
| Ungulate's hoof, essentially | 32 |
| Ungulate with a prehensile snout | 32 |
| Ungrammatical word before apples | 32 |
| Ungrammatical word before "apples" | 44 |
| Unger portrayer on "The Odd Couple" | 45 |
| Unfriendly seafood seller's stall? | 38 |
| Unfounded charge, to an alleged perp | 36 |
| Unfortunately, it may follow night | 34 |
| Unfortunately named Japanese chocolate company | 46 |
| Unfortunately common Chinese restaurant pun word | 48 |
| Unfortunate words with "the altar" | 44 |
| Unfortunate utterance from the trenches | 39 |
| Unfortunate things to have to count | 35 |
| Unfortunate sound when you bend over | 36 |
| Unfortunate landing spot for a parachutist | 42 |
| Unfortunate coal mine inhabitants | 33 |
| Unfortunate boy's name in a 1969 song | 41 |
| Unfortunate bottom line on an earnings report | 45 |
| Unforgettable time for historians | 33 |
| Unfolding view for a hapless hang-glider? | 41 |
| Unflinching in the face of pain, say | 36 |
| Unflattering metaphor for a female senior | 41 |
| Unflattering comparison for a fruitcake | 39 |
| Unfinished trilogy by Frank Norris | 34 |
| Unfinished James Grady work about time-sharing? | 47 |
| Unfinished Charles Darwin work about mints? | 43 |
| Unfilled part of a wine container | 33 |
| Unfeeling recommendation for the Tin Man? | 41 |
| Unfamiliar family reunion attendee | 34 |
| Unfairly outnumbers, with "on" | 40 |
| Unfairly low scores at the pool? | 32 |
| Unfair treatment, with "the" | 38 |
| Unexpectedly, it's usually made in Ecuador | 46 |
| Unexpected turn of events, as in a literary work | 48 |
| Unexpected telemarketing contact | 32 |
| Unexpected piece in a chicken order? | 36 |
| Unexpected listener's response | 34 |
| Unexpected attack, as of dizziness | 34 |
| Unexciting, low-paying position, in slang | 41 |
| Unexciting, low-paid work, in modern lingo | 42 |
| Unethical law enforcement practice | 34 |
| Unethical items in the antique business | 39 |
| Unethical campaign practices (30,6) | 35 |
| UNESCO World Heritage Site in Sicily | 36 |
| Unesco World Heritage Site in Jordan | 36 |
| Unerringly, after "to" | 32 |
| Unequivocal statement re this puzzle | 36 |
| Unenthusiastic response to an offer | 35 |
| Unenthusiastic reply to "How are you?" | 48 |
| Unemployment compensation, in Britain | 37 |
| Unemployed persons with full-time jobs | 38 |
| Unemotional one-night stand in feminist slang | 45 |
| Uneasy feeling regarding have-nots? | 35 |
| Uneasy about a farm team member? | 32 |
| Uneasy "bundle" contents | 34 |
| Unearthed pottery fragment: Var. | 32 |
| Unearth, with ''up'' | 36 |
| Undoer of "ritardando" | 32 |
| Undisputed leader at drawing walks? | 35 |
| Undeveloped but potentially useful | 34 |
| Undesirable result of making a pass?: Abbr. | 43 |
| Undesirable one, to Theodore Cleaver | 36 |
| Undesirable development around a city | 37 |
| Underworld overlord, in crookspeak | 34 |
| Underworld group, with "the" | 38 |
| Underworld entrance, to an Italian | 34 |
| Underwood and Studdard, affectionately | 38 |
| Underwear that never needs washing? | 35 |
| Underwear promoted by Michael Jordan | 36 |
| Underwater England/France connection | 36 |
| Underwater detection instruments | 32 |
| Underwater creature whose males give birth | 42 |
| Underwater "wolf pack" | 32 |
| Underthing that's part of a bleeped phrase? | 47 |
| Understudies for a star of "The Piano"? | 49 |
| Understandings of others' situations | 40 |
| Understand, according to Robert Heinlein | 40 |
| Understand the works of Courbet? | 32 |
| Understand spoken words without hearing them | 44 |
| Understand speech without hearing | 33 |
| Understand now, as someone's tricks | 39 |
| Undersized bats and gloves, e.g. | 32 |
| Underperforming investment, slangily | 36 |
| Underlying theme of "Se7en" | 37 |
| Underlying principle of the universe | 36 |
| Underlying pattern of the universe | 34 |
| Underhanded Massive Attack song? | 32 |