| ___ Mesa (San Diego border crossing) | 36 |
| ___ Men ("Who Let the Dogs Out?" group) | 49 |
| ___ Men ("Who Let the Dogs Out?" band) | 48 |
| ___ Men ("Who Let the Dogs Out" group) | 48 |
| ___ Men ("Who Let the Dogs Out" band) | 47 |
| ___ Men ("Move It Like This" group) | 45 |
| ___ Meir Tower, Israel's first skyscraper | 45 |
| ___ Megiddo (city of ancient Palestine) | 39 |
| ___ medicine (type of jurisprudence) | 36 |
| ___ medica (physician's treatise) | 37 |
| ___ mean square (statistics calculation) | 40 |
| ___ me tangere (something off-limits) | 37 |
| ___ me tangere (''touch me not'') | 49 |
| ___ McFly of "Back to the Future" | 43 |
| ___ McCheese (former fast-food character) | 41 |
| ___ May, surrogate mother for Spider-Man | 40 |
| ___ May, in "Tobacco Road" | 36 |
| ___ May of "Tobacco Road" | 35 |
| ___ May of "The Beverly Hillbillies" | 46 |
| ___ May Lester of "Tobacco Road" | 42 |
| ___ May in "Tobacco Road" | 35 |
| ___ maximi (butt muscles, scientifically) | 41 |
| ___ Matters (broadcasting watchdog) | 35 |
| ___ Matter ("Breaking Bad" corporation) | 49 |
| ___ Matsuhisa, celebrity chef and restaurateur | 46 |
| ___ Mather, clergyman-Harvard president | 39 |
| ___ maté (tealike beverage) | 34 |
| ___ Master's Voice (RCA trademark) | 38 |
| ___ Master's Voice (RCA logo) | 33 |
| ___ Mason (global investment management firm) | 45 |
| ___ Mason (financial services company) | 38 |
| ___ Mason (asset management firm) | 33 |
| ___ Masaryk, Czechoslovakia's first president | 49 |
| ___ Martin, Jim Rockford sidekick | 33 |
| ___ Martin (British car company) | 32 |
| ___ Marquez, Nickelodeon cartoon girl | 37 |
| ___ Maritimes, French department | 32 |
| ___ Maris (title of the Virgin Mary) | 36 |
| ___ Marie, noted shipwreck of circa 1700 | 40 |
| ___ Maria (coffee-flavored liqueur) | 35 |
| ___ marché (cheaply, in Paris) | 33 |
| ___ Marchand (rapper Foxy Brown's real name) | 48 |
| ___ Marchand (Foxy Brown's real name) | 41 |
| ___ March, Saul Bellow protagonist | 34 |
| ___ march on (slyly gain advantage) | 35 |
| ___ march on (beat to the punch) | 32 |
| ___ Marbles, British Museum magnet | 34 |
| ___ Marbles (famed Greek sculptures) | 36 |
| ___ Marbles (British Museum display) | 36 |
| ___ Manutius, printer-scholar: 1450–1515 | 47 |
| ___ Manutius, creator of italics | 32 |
| ___ Manning face (post-interception look) | 41 |
| ___ management class (therapy session) | 38 |
| ___ man (frequent article subject in The Onion) | 47 |
| ___ Malfoy, Harry Potter antagonist | 35 |
| ___ Malfoy, bully in Harry Potter books | 39 |
| ___ Malfoy (Harry Potter villain) | 33 |
| ___ Malenkov, former U.S.S.R. prime minister | 44 |
| ___ mal (tort reform topic, briefly) | 36 |
| ___ Major (southern constellation) | 34 |
| ___ Major (Sirius's constellation) | 38 |
| ___ Major (Dog Star's locale) | 33 |
| ___ Major (Big Dipper's constellation) | 42 |
| ___ Major (Big Dipper constellation) | 36 |
| ___ Major ("Great Bear" constellation) | 48 |
| ___ Major (''The Great Bear'') | 46 |
| ___ Maj. (top-ranked USMC noncom) | 33 |
| ___ maison (French for “indoors”) | 41 |
| ___ magna, prelate's vestment | 33 |
| ___ Magna (annual early-music festival) | 39 |
| ___ magica (alchemist's work) | 33 |
| ___ Mae Martinez (early female pro wrestler) | 44 |
| ___ Mae Brown (Whoopi's Oscar-winning role) | 47 |
| ___ Mae Brown ("Ghost" role) | 38 |
| ___ Mae (Whoopi's "Ghost" role) | 45 |
| ___ Mae (college money provider) | 32 |
| ___ Mae ("Ghost" role) | 32 |
| ___ Macmillan, classmate of Harry Potter | 40 |
| ___ machine (restaurant fixture) | 32 |
| ___ Machine (Late 80s David Bowie band) | 39 |
| ___ MacGraw "Love Story" co-star | 42 |
| ___ Maass, nurse on a 13¢ stamp | 34 |
| ___ Maar (Picasso mistress and subject) | 39 |
| ___ Luthor, of "Superman" | 35 |
| ___ Luthor of "Superman" | 34 |
| ___ Lupin, the Prince of Thieves | 32 |
| ___ Lung, Chinese emperor: 18th century | 39 |
| ___ Lund of "Casablanca" | 34 |
| ___ lunch (quits working to eat) | 32 |
| ___ lunch (note on an office door) | 34 |
| ___ Lumumba, Congo's first P.M. | 35 |
| ___ Lucia Cortez, "Lost" castaway | 43 |
| ___ Lowry, children's writer | 32 |
| ___ Low, N.Y.C. mayor: 1901–3 | 36 |
| ___ Lovelace, computer programming pioneer | 42 |
| ___ Lovegood (friend of Harry Potter) | 37 |
| ___ Louise of "Gilligan's Island" | 47 |
| ___ Lor-Van, Superman's biological mother | 45 |
| ___ Loops (breakfast cereal brand) | 34 |
| ___ Loompa (Wonka chocolate factory worker) | 43 |