| Sea of Tranquillity, for the Apollo 11 astronauts | 49 |
| Sea of __, shallowest in the world | 34 |
| Sea of ___ (arm of the Black Sea) | 33 |
| Sea of ___ (Don River's receiver) | 37 |
| Sea of ___ (section of the Black Sea) | 37 |
| Sea of ___ (setting of the Gulf of Taganrog) | 44 |
| Sea of ___ (view from Crimea's eastern coast) | 49 |
| Sea of ___ between Russia and Ukraine | 37 |
| Sea of ___, arm of the Black Sea | 32 |
| Sea of ___, south of the Cyclades | 33 |
| Sea on the Kazakhstan-Uzbekistan border | 39 |
| Sea once dotted with 1,500-plus islands | 39 |
| Sea once fed by the Amu Darya River | 35 |
| Sea once the world's fourth-largest lake | 44 |
| Sea separating Greece from Turkey | 33 |
| Sea shared by Uzbekistan and Kazakstan | 38 |
| Sea that is an environmental disaster | 37 |
| Sea that lies north of the Kerch Strait | 39 |
| Sea that's home to Vozrozhdeniye Island | 43 |
| Sea that's lost over 75% of its surface area | 48 |
| Sea that's sometimes called a lake | 38 |
| Sea under Italy's "boot" | 38 |
| Sea witch in "The Little Mermaid" | 43 |
| Sea ___ (Seattle NFL cheerleaders) | 34 |
| Sea ___, animal that contracts when touched | 43 |
| Sea ___, denizen of the North Pacific | 37 |
| Seabees' "Can Do" is one | 38 |
| Seabird native to the Galápagos Islands | 42 |
| Seabird that can be "sooty" | 37 |
| Seabird that just completed its Ph.D.? | 38 |
| Seabirds that make braying sounds | 33 |
| Seabiscuit's last race place | 32 |
| Seabound Paul Simon song, with "The"? | 47 |
| Seacrest of ''American Idol'' | 45 |
| Seacrest of "American Idol" | 37 |
| Seacrest succeeded him in '04 | 33 |
| Seafood dish that's rather a mess? | 38 |
| Seafood fritters, Japanese style | 32 |
| Seafood restaurant counter, perhaps | 35 |
| Seafood salad ingredient, perhaps | 33 |
| Seafood sauce enjoyed by actor Neeson? | 38 |
| Seafood selection from the North Atlantic | 41 |
| Seafood serving at a Beatle's house? | 40 |
| Seagoing departure from a Scandinavian capital? | 47 |
| Seagoing vessel that's shot? | 32 |
| Seagram's Seven Crown or Four Roses | 39 |
| Seal in, as a steak's juices | 32 |
| Seal's resting place, perhaps | 33 |
| Sealed again, as a champagne bottle | 35 |
| Sealed so as not to allow seepage | 33 |
| Sealer that might close a love letter envelope | 46 |
| Seals & Crofts' forecast song | 37 |
| Seals and Crofts "Takin' ___" | 43 |
| Seals's partner in 1970s music | 34 |
| Seaman apprentices' USMC equivalents | 40 |
| Seaman in a ceremonial honor guard | 34 |
| Seaman's "You bet" | 32 |
| Seaman's call for assistance | 32 |
| Seaman-novelist who served on the Pilgrim | 41 |
| Seamstress in "La Bohème" | 38 |
| Seamstress' ''oops''? | 41 |
| Seamstress' cry upon making a mistake? | 42 |
| Seamstress's concealed interlacement | 40 |
| Sean Bean's character in "Jacob" | 46 |
| Sean Connery and Roger Moore, e.g. | 34 |
| Sean Connery and Tilda Swinton, e.g. | 36 |
| Sean Connery's first Bond film | 34 |
| Sean Connery's first film as 007 | 36 |
| Sean Connery, nationally speaking | 33 |
| Sean Connery: "The Man Who ___" (1975) | 48 |
| Sean Connery’s costar in “The Rock” | 47 |
| Sean Hannity, lately, and others | 32 |
| Sean John, P. Diddy, or just plain Diddy | 40 |
| Sean Kingston's "___ War" | 39 |
| Sean of ''Lord of the Rings'' | 45 |
| Sean of ''The Game'' | 36 |
| Sean of ''The Lord of the Rings'' | 49 |
| Sean of 'The Lord of the Rings' | 39 |
| Sean of "Boy Meets Girl" | 34 |
| Sean of "Dead Man Walking" | 36 |
| Sean of "Lord of the Rings" | 37 |
| Sean of "Lord of the Rings" films | 43 |
| Sean of "LOTR: The Two Towers" | 40 |
| Sean of "The Lord of the Rings" | 41 |
| Sean of "The Lord of the Rings" films | 47 |
| Sean of "Will & Grace" | 36 |
| Sean of the "Lord of the Rings" films | 47 |
| Sean of the "Lord of the Rings" series | 48 |
| Sean of the "Lord of the Rings" trilogy | 49 |
| Sean Paul "Don't ___ Me" | 38 |
| Sean Penn's daughter in 'I Am Sam' | 46 |
| Sean who wrote "Juno and the Paycock" | 47 |
| Sean's "Dr. No" Bond girl | 39 |
| Sean's "Dr. No" co-star | 37 |
| Seaport 90 miles SSW of Key West | 32 |
| Seaport and export of the Netherlands | 37 |
| Seaport in France's Finistère department | 47 |
| Seaport in the European part of Russia | 38 |
| Seaport on the east coast of Jutland | 36 |
| Seaport on the east coast of Jutland (Var.) | 43 |