| Unseen "Mork & Mindy" character | 45 |
| Unseen "Frasier" character | 36 |
| Unseen "Fiddler on the Roof" tyrant | 45 |
| Unsealed bottle at the perfume counter | 38 |
| Unseal surreptitiously, as an envelope | 38 |
| Unscrambles a secret transmission | 33 |
| Unscientific means of getting results | 37 |
| Unscheduled appointment book column | 35 |
| Unsatisfying response to "Why?" | 41 |
| Unsatisfying reply to a question | 32 |
| Unsatisfied person's request | 32 |
| Unsanctioned workplace demonstration | 36 |
| Unsanctioned class communicators | 32 |
| Unsafe thing in a room full of rocking chairs? | 46 |
| Unrhymed poetry, usually in iambic pentameter | 45 |
| Unrewarding career, as coined by Douglas Coupland | 49 |
| Unrestrained Kentucky Derby entrant? | 36 |
| Unrestrained expression of emotion | 34 |
| Unrepentant response to an accusation | 37 |
| Unrepentant individual, Biblically | 34 |
| Unremarkable batting performance | 32 |
| Unreliable communication method (h) | 35 |
| Unrecoverable investment expenses | 33 |
| Unrealized hit taken on an investment | 37 |
| Unrealized gain on an investment | 32 |
| Unrealized 60's Boeing project | 34 |
| Unrealistically idealistic state | 32 |
| Unread part of a movie review, maybe | 36 |
| Unquestioned style, hiding urban transit | 40 |
| Unprosperous time, metaphorically | 33 |
| Unprepared, as a sprinter in the blocks | 39 |
| Unprepared tourist's surprise | 33 |
| Unpremeditated homicide (nonsexist style) | 41 |
| Unpredictable "Mask" actor? | 37 |
| Unpopular player at a blackjack table | 37 |
| Unpopular ophthalmologist's implement? | 42 |
| Unpopular classification, in the 60's | 41 |
| Unpopular animal in a china shop? | 33 |
| Unpleasant, paved-over urban spaces | 35 |
| Unpleasant way to catch one's spouse | 40 |
| Unpleasant obligation to move, in chess | 39 |
| Unpleasant consequence, figuratively | 36 |
| Unpleasant cause of being woken up | 34 |
| Unpleasant but indispensable parts of a job | 43 |
| Unpleasant alternatives, figuratively | 37 |
| Unorthodox, untraditional leaders | 33 |
| Unoriginal order, with "the" | 38 |
| Unofficial, like some university degrees | 40 |
| Unoccupied Middle Easterner, as of last month | 45 |
| Unobtrusive, as a ringtone setting | 34 |
| Unnominated film with a fuzzy subject? | 38 |
| Unnominated film with a corny plot? | 35 |
| Unnominated film featuring Inspector Clouseau? | 46 |
| Unnerving way to hand in your job application | 45 |
| Unnerving subject of an IRS notice | 34 |
| Unnecessary words cluttering wise sayings? | 42 |
| Unnecessary person, on a double date | 36 |
| Unnecessary business advice for a stripper? | 43 |
| Unnatural desire to eat chalk, ashes, etc. | 42 |
| Unnamed source of a secret, playfully | 37 |
| Unmoved audience member, metonymically | 38 |
| Unmarried partner, to the Census Bureau | 39 |
| Unmarried partner, in modern lingo | 34 |
| Unmanned, unsettling military flier | 35 |
| Unmanned vessel that found the Titanic | 38 |
| Unmanned vehicle that found the Titanic | 39 |
| Unmanned sub that found the Titanic | 35 |
| Unmanned space probe launched Aug. 20, 1977 | 43 |
| Unmanned NASA mission of the '70s | 37 |
| Unmanned craft that makes targeted attacks | 42 |
| Unmanageable horses, in the Southwest | 37 |
| Unmake a mess (with "up") | 35 |
| Unlucky number, in ancient Rome? | 32 |
| Unlucky investor's loss, proverbially | 41 |
| Unlucky fisherman's haul, in cartoons | 41 |
| Unlucky fisherman's catch, in comics | 40 |
| Unliquefiable money at the snow bank? | 37 |
| Unlikely-to-be-fulfilled concert requests | 41 |
| Unlikely trait for a musicologist | 33 |
| Unlikely to rattle or squeak, say | 33 |
| Unlikely to raise one's hand in class | 41 |
| Unlikely to produce a clothing line? | 36 |
| Unlikely to hang with the in-crowd | 34 |
| Unlikely to develop clothing lines? | 35 |
| Unlikely to be in the travel guides | 35 |
| Unlikely to accede to the throne | 32 |
| Unlikely stop for a restaurant reviewer | 39 |
| Unlikely sign on a lawyer's door? | 37 |
| Unlikely section in a religious bookstore | 41 |
| Unlikely prom kings (though there are exceptions) | 49 |
| Unlikely pride parade participant | 33 |
| Unlikely Playboy Channel watcher | 32 |
| Unlikely Planned Parenthood member | 34 |
| Unlikely place to take one's business | 41 |
| Unlikely place for his-and-hers towels | 38 |
| Unlikely pet for Margaret's rec room | 40 |
| Unlikely number for a rock concert | 34 |
| Unlikely nickname for a beanpole | 32 |
| Unlikely job for one with acrophobia? | 37 |
| Unlikely Hail Mary results: Abbr. | 33 |