| Residents practice in them (abbr.) | 34 |
| Residue from Eyjafjallajökull | 32 |
| Residue left after alcohol has been distilled | 45 |
| Resign (with ''down'') | 38 |
| Resign, after consulting with a lawyer? | 39 |
| Resigning employee's courtesy | 33 |
| Resinous juice used in perfumery | 32 |
| Resinous substance found in incense | 35 |
| Resinous substance used as an arrow poison | 42 |
| Resistance following Saddam's downfall | 42 |
| Resistance of a liquid to shear forces | 38 |
| Resistance-free guarding in basketball | 38 |
| Resistant to melting, as certain metals | 39 |
| Resisted the temptation to get involved | 39 |
| Resnick's "___ Shadow" | 36 |
| Resolve (with ''out'') | 38 |
| Resolve a longstanding disagreement | 35 |
| Resolve amicably, as an argument | 32 |
| Resolve, with ''out'' | 37 |
| Resolved a dispute in the style of Aaron Burr | 45 |
| Resonance in some regional dialects | 35 |
| Resort area in the Catskills, informally | 40 |
| Resort area on the U.S./Canada border | 37 |
| Resort at the base of the Sierra Nevadas | 40 |
| Resort city along the Roaring Fork River | 40 |
| Resort city east of Santa Barbara | 33 |
| Resort feature that can give you a lift | 39 |
| Resort hidden in the five longest puzzle answers | 48 |
| Resort in "Couples Retreat" | 37 |
| Resort in Colorado's Pitkin County | 38 |
| Resort island in 1975's top-grossing film | 45 |
| Resort island northeast of Sydney | 33 |
| Resort island south of Cancún | 32 |
| Resort island with a noted seal colony | 38 |
| Resort known for its mineral waters | 35 |
| Resort near Arapaho National Forest | 35 |
| Resort near Castle Peak, Colorado | 33 |
| Resort near the Rio Grande Gorge | 32 |
| Resort near the White River National Forest | 43 |
| Resort on the Roaring Fork River | 32 |
| Resort on the southern tip of Baja | 34 |
| Resort port where Alfred Nobel died | 35 |
| Resort that sounds like a face mask | 35 |
| Resort town for video game enthusiasts? | 39 |
| Resort town W. of the Delaware Water Gap | 40 |
| Resource in the game Settlers of Catan | 38 |
| Respect from the talk show host, e.g.? | 38 |
| Respect that one deserves, in slang | 35 |
| Respectful title for God, in Hebrew | 35 |
| Respectful title in British India | 33 |
| Respectful, affirmative response | 32 |
| Respectfully give the final word | 32 |
| Respects the environment, in a way | 34 |
| Respighi work, with "The" | 35 |
| Respighi's "--- of Rome" | 38 |
| Respighi's "Pini di ___" | 38 |
| Respighi's "The ___ of Rome" | 42 |
| Respighi's "___ of Rome" | 38 |
| Respighi's "___ Rome" | 35 |
| Respighi's "____ of Rome" | 39 |
| Respiratory disease in 2002 news | 32 |
| Respite from a stressful job, perhaps | 37 |
| Respite from dependents and everyone else | 41 |
| Respond angrily, with "out" | 37 |
| Respond on "Jeopardy!" | 32 |
| Respond properly on "Jeopardy!" | 41 |
| Respond quickly to the unexpected | 33 |
| Respond to "I didn't catch that" | 46 |
| Respond to "I didn't get it" | 42 |
| Respond to "Let's hear it ..." | 44 |
| Respond to a bumper sticker, perhaps | 36 |
| Respond to a busy signal, perhaps | 33 |
| Respond to a doctor's request | 33 |
| Respond to a live radio show, perhaps | 37 |
| Respond to a really bad joke, maybe | 35 |
| Respond to a shaman's efforts | 33 |
| Respond to a strong head butt, perhaps | 38 |
| Respond to an "I Want You" poster | 43 |
| Respond to an electrifying play, perhaps | 40 |
| Respond to one who won't go quietly | 39 |
| Respond to sunburn, a couple days later | 39 |
| Respond to the Jonas Brothers, say | 34 |
| Respond to the raising of a hand | 32 |
| Respond to Uncle Sam's poster request | 41 |
| Responded on "Jeopardy!" | 34 |
| Responded to a bailiff's request | 36 |
| Responded to a dentist's request | 36 |
| Responded to one on his knee, to his delight | 44 |
| Responded to opportunity's knock | 36 |
| Responded to, as a stoolie's tip | 36 |
| Responded, on "Jeopardy!" | 35 |
| Responders to "Sic 'em!" | 38 |
| Responding to medication, perhaps | 33 |
| Responds à la "Jeopardy!" | 38 |
| Responds àla "Jeopardy!" | 42 |
| Responds in ''Jeopardy!'' | 41 |
| Responds in "Jeopardy!" | 33 |
| Responds on "Jeopardy!" | 33 |
| Responds promptly to an assignment from the boss | 48 |
| Responds to ''May I cut in?'' | 45 |