| "___ my brother's keeper?": Gen. | 46 |
| "___ my brother's keeper?": Cain | 46 |
| Role for which Whitaker won Best Actor of 2006 | 46 |
| Key of Brahms' "Double Concerto" | 46 |
| Old song ''Abdul Abulbul ___'' | 46 |
| "One Fat Englishman" author Kingsley | 46 |
| San Francisco record shopper's destination | 46 |
| "Down ___ the Sugar Cane," 1908 song | 46 |
| 19th-century journalist/politician ___ Kendall | 46 |
| "My Cherie ___" (Stevie Wonder song) | 46 |
| "My Cherie ---" (Stevie Wonder song) | 46 |
| Actress Adams of "Julie & Julia" | 46 |
| "The Party Faithful" author Sullivan | 46 |
| Doña ___, "The Violent Land" lady | 46 |
| "___ Ng" (They Might Be Giants song) | 46 |
| Any of four long pairs featured in this puzzle | 46 |
| Burton's "The ___ of Melancholy" | 46 |
| "Grey's ___" (hospital TV drama) | 46 |
| "Isn't there more to the story?" | 46 |
| Author of the travelogue "In Sweden" | 46 |
| Actress MacDowell of "Groundhog Day" | 46 |
| The AP's "Driver of the Century" | 46 |
| One of three words meaning "excuses" | 46 |
| "___ to bed" ("goodnight") | 46 |
| "--- to bed" ("goodnight") | 46 |
| He was "goofing on Elvis," to R.E.M. | 46 |
| "___ Gang" ('50s kids' show) | 46 |
| "___ Gang" (50's kids' show) | 46 |
| "Gimme _____!" (end of a Yale cheer) | 46 |
| Blood cell deficiency that may cause dizziness | 46 |
| Janis Ian album "Working Without __" | 46 |
| "They hunt . . . with ___": Mic. 7:2 | 46 |
| Words before and after ''for'' | 46 |
| "Sense and Sensibility" director Lee | 46 |
| Cocteau's "L'___ Heurtebise" | 46 |
| "Murder, She Wrote" actress Lansbury | 46 |
| Actress Pier of "The Silver Chalice" | 46 |
| What Horace called "a short madness" | 46 |
| "Touch me with noble ___": King Lear | 46 |
| Dickinson of TV's "Police Woman" | 46 |
| Tricky thing to trisect, in classical geometry | 46 |
| "Wheel of Fortune" purchase, perhaps | 46 |
| Nickname in the "Star Wars" prequels | 46 |
| "Up Up Up Up Up Up" singer Di Franco | 46 |
| 'Gimme --!' (start of a cheer at Iowa) | 46 |
| ''Wheel of Fortune'' purchase? | 46 |
| "The Pilot's Wife" author Shreve | 46 |
| She wrote "Gentlemen Prefer Blondes" | 46 |
| Sinatra's "My Way" lyricist Paul | 46 |
| "(You're) Having My Baby" singer | 46 |
| Paul who wrote and sang "Lonely Boy" | 46 |
| Modern name for the capital of ancient Galatia | 46 |
| Curry who formerly co-hosted "Today" | 46 |
| ''Black Beauty'' author Sewell | 46 |
| ''Getting to Know You'' singer | 46 |
| Fashion designer behind the fragrance Rock Me! | 46 |
| "The Princess Diaries" star Hathaway | 46 |
| Portrayer of Jane in "Becoming Jane" | 46 |
| "The Vampire Chronicles" author Rice | 46 |
| Oscar nominee for "Fatal Attraction" | 46 |
| Alvy's love interest in a Woody Allen film | 46 |
| Diane Keaton role that sparked a fashion craze | 46 |
| ''__ Song'' (John Denver tune) | 46 |
| What "A" may stand for on a monument | 46 |
| "And giving ___, up the chimney ..." | 46 |
| Electrochemically conductive battery component | 46 |
| "You're ___ Smoothie," 1932 song | 46 |
| "You can't teach ___ dog . . . " | 46 |
| "I'll send for you ___": Othello | 46 |
| "Author" of the observation, briefly | 46 |
| "___ One Bites the Dust" (Queen hit) | 46 |
| Potsie on "Happy Days," ___ Williams | 46 |
| "The ___ and the Grasshopper": Aesop | 46 |
| Something that might get a rise out of people? | 46 |
| Antihero of "No Country for Old Men" | 46 |
| Lover in Dryden's "All for Love" | 46 |
| "Friends, Romans, countrymen" orator | 46 |
| Who was "Marching," to Dave Matthews | 46 |
| Six-footers that even short people tower over? | 46 |
| It's across the Albert Canal from Liège | 46 |
| "Neither can you crack ___": Emerson | 46 |
| Shania Twain's "___ Man of Mine" | 46 |
| “___ Dream Will Do” (Webber/Rice song) | 46 |
| "Alice Doesn't Live Here" closer | 46 |
| "I wouldn't do this for just __" | 46 |
| ''All systems go,'' in letters | 46 |
| Co. that purchased the Huffington Post in 2011 | 46 |
| "You've got mail" Internet giant | 46 |
| One who hears "You've got mail!" | 46 |
| Those who hear "You've got mail" | 46 |
| ___ Center, second-tallest building in Chicago | 46 |
| "What __!": "How annoying" | 46 |
| " . . . get you ___ of horns": Shak. | 46 |
| "Be ___!" ("Help me out!") | 46 |
| "Be on the lookout" signal, in brief | 46 |
| "Great" or "lesser" animal | 46 |
| “The Naked ___” (Desmond Morris title) | 46 |
| Kim Hunter played one opposite Charlton Heston | 46 |
| "___ Escape" (1999 PlayStation game) | 46 |
| As vertical as possible, as an embedded anchor | 46 |