| Major tractor manufacturer | 26 |
| Major supporters of the ACA | 27 |
| Major Spanish port city | 23 |
| Major silicone manufacturer | 27 |
| Major sight in the sky? | 23 |
| Major shipbuilding city | 23 |
| Major sector of the psyche | 26 |
| Major seaport of South Afr. | 27 |
| Major school of Buddhism | 24 |
| Major school assignment | 23 |
| Major Scandinavian seaport | 26 |
| Major Republican funder | 23 |
| Major record label, once | 24 |
| Major recessions affect them | 28 |
| Major province in Afghanistan | 29 |
| Major producers of oil | 22 |
| Major producer of raspberries | 29 |
| Major processing center | 23 |
| Major Postal Service client | 27 |
| Major port on Osaka Bay | 23 |
| Major port of Old Rome | 22 |
| Major Pierce portrayer | 22 |
| Major pest in the South | 23 |
| Major personal annoyance | 24 |
| Major peanut purchaser | 22 |
| Major patent seller of 2013 | 27 |
| Major Pasadena thoroughfare | 27 |
| Major part or the whole thing | 29 |
| Major paperback publisher | 25 |
| Major paper, for short | 22 |
| Major or Thatcher, e.g. | 23 |
| Major or Mrs. of old comics | 27 |
| Major or Minor predecessor | 26 |
| Major or Minor preceder | 23 |
| Major or Minor lead-in | 22 |
| Major or minor follower | 23 |
| Major or minor constellation | 28 |
| Major or Minor beginning | 24 |
| Major or minor arm muscle | 25 |
| Major or major general | 22 |
| Major or kitchen follower | 25 |
| Major or disk follower | 22 |
| Major olive oil exporter | 24 |
| Major Old West cattle route | 27 |
| Major oil refinery port | 23 |
| Major Nuovo Testamento writer | 29 |
| Major Nile cataract locale | 26 |
| Major network initials | 22 |
| Major name in mathematics | 25 |
| Major name in insurance | 23 |
| Major name in frozen foods | 26 |
| Major musical composition | 25 |
| Major month for matrimony | 25 |
| Major mode of transportation? | 29 |
| Major mo. for campaigners | 25 |
| Major military headquarters | 27 |
| Major midwestern airport | 24 |
| Major Middle Eastern airline | 28 |
| Major market for U.S. exports | 29 |
| Major manufacturing continent | 29 |
| Major maker of water filters | 28 |
| Major maker of beverage cans | 28 |
| Major mail handler?: Abbr. | 26 |
| Major loss, figuratively | 24 |
| Major leagues, slangily | 23 |
| Major leagues, in slang | 23 |
| Major leaguers, 1969-2004 | 25 |
| Major Leaguer Stephen or J.D. | 29 |
| Major leaguer in Canada | 23 |
| Major league, slangily | 22 |
| Major League work stoppage | 26 |
| Major League V.I.P.'s | 25 |
| Major League pitcher, e.g. | 26 |
| Major league pitcher Car-los | 28 |
| Major League manager Larry | 26 |
| Major League league: Abbr. | 26 |
| Major league family surname | 27 |
| Major league family name | 24 |
| Major League Baseball V.I.P. | 28 |
| Major league ball team | 22 |
| Major label broken up in 2012 | 29 |
| Major kitchen appliance | 23 |
| Major Kazakhstani export | 24 |
| Major Joppolo's town | 24 |
| Major Joppolo's post | 24 |
| Major Japanese seaport | 22 |
| Major Japanese carrier | 22 |
| Major Italian tourist site | 26 |
| Major Italian fashion house | 27 |
| Major Istanbul attraction | 25 |
| Major interest, slangily | 24 |
| Major industry of Madeira | 25 |
| Major Indonesian export | 23 |
| Major impact, as of an attack | 29 |
| Major hurricane of 2008 | 23 |
| Major hurricane of 2005 | 23 |
| Major hurdle, metaphorically | 28 |
| Major Houlihan portrayer | 24 |
| Major Hoople's word | 23 |
| Major Hoople's holler | 25 |