| One defeated at Châlons in 451 | 33 |
| One defintion of ''can'' | 40 |
| One demonstrating excellent service? | 36 |
| One department of a landscaping company? | 40 |
| One Direction "Tell Me ___" | 37 |
| One dismounting from a horse, maybe | 35 |
| One dispatching wise guys to the moon? | 38 |
| One doing blackjack-table arithmetic | 36 |
| One doing commercial endorsements, maybe | 40 |
| One dressed as Vulcan ambassador Sarek, probably | 48 |
| One dressed in white, stereotypically | 37 |
| One driving a car with two brakes, often | 40 |
| One eager to climb every mountain | 33 |
| One eager to see how the other half lives, say | 46 |
| One edition of the Wall Street Journal | 38 |
| One eighth of a famous flying team | 34 |
| One employing trompe l'oeil effects | 39 |
| One enamored of early Europeans? | 32 |
| One encountered in a close encounter | 36 |
| One encouraged to drink on the job | 34 |
| One end of a digression, for short? | 35 |
| One end of a homemade walkie-talkie | 35 |
| One end of New York's Triborough Bridge | 43 |
| One end of Ontario's Welland Canal | 38 |
| One end of St. George's Channel | 35 |
| One end of the political spectrum | 33 |
| One endlessly smoothing things over? | 36 |
| One enrolled in obedience school | 32 |
| One ensuring army equipment works | 33 |
| One eschewing the opposite field | 32 |
| One evidently not filing a flight plan | 38 |
| One expecting you to question his answer? | 41 |
| One experienced in presidential politics? | 41 |
| One explanation for not wanting to go to a movie | 48 |
| One expressing the same thoughts | 32 |
| One fashioning an auto from clay? | 33 |
| One favoring a strong central government | 40 |
| One favoring a strong, centralized government | 45 |
| One feeling alienated in Wisconsin, perhaps | 43 |
| One fell on Chicken Little's head | 37 |
| One finishing a marathon in eight hours, say | 44 |
| One First Lady's maiden name | 32 |
| One fleeing persecution, perhaps | 32 |
| One floundering in strange surroundings | 39 |
| One following a bellwether, maybe | 33 |
| One for the "no" column | 33 |
| One for whom a street may be named | 34 |
| One for whom all roads lead to roam | 35 |
| One for whom all roads lead to roam? | 36 |
| One for whom Apr. is the cruelest month? | 40 |
| One for whom glasses are clinked | 32 |
| One for whom many angles may be right? | 38 |
| One for whom nothing's good enough | 38 |
| One for whom silicosis is an occupational hazard | 48 |
| One for whom the play's the thing | 37 |
| One for whom there's no hope | 32 |
| One for whose benefit a legal suit is brought | 45 |
| One forbidden to kiss for pleasure | 34 |
| One form of a multiform organism | 32 |
| One form of the Egyptian god Set | 32 |
| One found in a zebra crossing, for short | 40 |
| One found in a zebra crossing, maybe | 36 |
| One found just around the block? | 32 |
| One found on a computer screen or movie screen | 46 |
| One frequently taken advantage of | 33 |
| One frequently taking a time out | 32 |
| One from column A, one from column B, etc. | 42 |
| One from the Leaning Tower's city | 37 |
| One from Tripolis, in ancient Greece | 36 |
| One from whom property is transferred | 37 |
| One full of surprises or shocking news, e.g. | 44 |
| One generating a lot of interest? | 33 |
| One getting a single or a double, e.g. | 38 |
| One getting a tan the old-fashioned way | 39 |
| One getting laughs at others' expense | 41 |
| One getting lots of doubles and home runs, say | 46 |
| One getting messages by word of mouth? | 38 |
| One getting on-the-job-training, maybe | 38 |
| One getting one-on-one instruction | 34 |
| One getting out before the storm | 32 |
| One getting same-day medical service, maybe | 43 |
| One getting strokes, in a good way | 34 |
| One getting stuck in a horror movie | 35 |
| One given "unto us," in Isaiah | 40 |
| One given a red-carpet reception | 32 |
| One given away by her father, often | 35 |
| One given to sprees on horseback? | 33 |
| One giving shots on a horse farm? | 33 |
| One giving Starbuck's orders | 32 |
| One goes along the 38th parallel, briefly | 41 |
| One goes through these to get to the majors | 43 |
| One going back and forth to work | 32 |
| One going back and forth to work? | 33 |
| One going from theater to theater? | 34 |
| One going on long Saturday bike rides, maybe | 44 |
| One going over telemarketing lines | 34 |
| One going through a tunnel, perhaps | 35 |
| One going through papers in a safe, say | 39 |
| One going through the exercises? | 32 |
| One going to Afghanistan, probably | 34 |