| Problem that's hard to face? | 32 |
| Problem treated by an ophthalmologist | 37 |
| Problem treated with adaptive servo-ventilation | 47 |
| Problem with an organ near a temple? | 36 |
| Problem with CDs or records, but not so much MP3s | 49 |
| Problem with one's reasoning | 32 |
| Problem with this clue's answer | 35 |
| Problem-solving research institute | 34 |
| Problematic for hospital admissions | 35 |
| Problems addressed by podiatrists | 33 |
| Problems for parents and babysitters | 36 |
| Problems for workers with ambitions | 35 |
| Problems with a beta version, say | 33 |
| Procedural that aired its 250th episode in 2011 | 47 |
| Procedure done with a tummy tuck | 32 |
| Procedure during pregnancy, for short | 37 |
| Procedure for a burn victim, perhaps | 36 |
| Procedure for men hoping to look younger | 40 |
| Procedure that can detect brain tumors: Abbr. | 45 |
| Procedure that might precede defibrillation | 43 |
| Procedure that records the beat: Abbr. | 38 |
| Procedure to "jump through" | 37 |
| Procedures for detecting carpal fractures | 41 |
| Procedures for meeting performance criteria | 43 |
| Procedures involving suction, familiarly | 40 |
| Procedures seen on extreme makeover shows | 41 |
| Proceed after getting doubles in Monopoly | 41 |
| Proceed so as to avoid radar detection | 38 |
| Proceed unerringly toward, as a target | 38 |
| Proceed with difficulty (through) | 33 |
| Proceeded further than expected, say | 36 |
| Proceeded through a traffic jam, e.g. | 37 |
| Proceeded toward a target, with "in" | 46 |
| Proceeds from a smashing success? | 33 |
| Proceeds steadily with difficulty | 33 |
| Process associated with socialism | 33 |
| Process at work in settlement discussions | 41 |
| Process at work in some hearings | 32 |
| Process by which an organism releases energy | 44 |
| Process by which one cell becomes two | 37 |
| Process involving illegal drug profits, say | 43 |
| Process leading up to childbirth | 32 |
| Process of assimilating U.S. customs | 36 |
| Process of grooming and dressing oneself | 40 |
| Process of growing grass for cows? | 34 |
| Process of nature by which all things change | 44 |
| Process of taking hair off a fraidy-cat? | 40 |
| Process that involves drying out, for short | 43 |
| Process that went wrong in “The Fly” | 44 |
| Processes during checkout, as a credit card | 43 |
| Processes for saving scrap metal | 32 |
| Processor created by Apple, IBM and Motorola | 44 |
| Processor speed, hard disk space, etc. | 38 |
| Proclaimer of first Thanksgiving | 32 |
| Proclaimers "___ I Met You" | 37 |
| Proclamation of complete innocence | 34 |
| Proclivity for Cerf's writing? | 34 |
| Procol Harum "___ Shade of Pale" | 42 |
| Procol Harum "___ Street Blues" | 41 |
| Procrastination's result, sometimes | 39 |
| Procrastinator's colloquial promise | 39 |
| Procrastinator's comeuppance, perhaps | 41 |
| Procrastinator's pick-up line? | 34 |
| Procrastinator's reply, sometimes | 37 |
| Procrastinator's shopping day, maybe | 40 |
| Procrastinator's shopping day, perhaps | 42 |
| Procrastinator's time of action | 35 |
| Procrastinator's utterance, sometimes | 41 |
| Procrastinator's word, in Tampico | 37 |
| Procter & Gamble best seller | 32 |
| Procter & Gamble hair-care line | 35 |
| Procter & Gamble laundry brand | 34 |
| Procter & Gamble laundry product | 36 |
| Procter & Gamble pet food brand | 35 |
| Procter & Gamble pet food company | 37 |
| Procter & Gamble skin care brand | 36 |
| Procter of "CSI: Miami" | 33 |
| Proctor & Gamble cleansing product | 38 |
| Proctor __: kitchen appliance brand | 35 |
| Proctor ___ (small appliance brand) | 35 |
| Proctor's cry at the end of a test | 38 |
| Proctor-___ (kitchen appliance brand) | 37 |
| Proctor-___ (small appliance maker) | 36 |
| Procure off-site, as goods and services | 39 |
| Prod. that sometimes has a cradle | 33 |
| Prodigal's reward?: Luke 15:23 | 34 |
| Prodigy song about classic horror movie? | 40 |
| Produce gift that keeps on coming | 33 |
| Produce hurriedly, with "out" | 39 |
| Produce, as page layouts for a printer | 38 |
| Produced "splitting images" | 37 |
| Produced and deposited, as an egg | 33 |
| Produced sparks, as in a microwave | 34 |
| Producer for 50 Cent, familiarly | 32 |
| Producer of "They Live By Night," 1948 | 48 |
| Producer of "whirlybirds" | 35 |
| Producer of 1873's Peacemaker | 33 |
| Producer of a big accident? [1998, 2000, 1960] | 46 |
| Producer of a colorful ring tone | 32 |
| Producer of a hair-raising experience? | 38 |