| Interstate highway fixtures | 27 |
| Interstate misadventure | 23 |
| Interstate pull-off point | 25 |
| Interstate sign with an arrow | 29 |
| Interstate sign: Abbr. | 22 |
| Interstate speed limit, often | 29 |
| Interstate stopping point | 25 |
| Interstate through Chicago | 26 |
| Interstate through Houston | 26 |
| Interstate-building prez | 24 |
| Interstate-championing prez | 27 |
| Interstates, e.g.: Abbr. | 24 |
| Interstellar dust cloud | 23 |
| Interstellar gas cloud | 22 |
| Interstellar space clouds | 25 |
| Interstellar space vessel | 25 |
| Interstellar valet's job? | 29 |
| Interval in an athletic game | 28 |
| Interval of inactivity | 22 |
| Interval of three whole steps | 29 |
| Intervals between events | 24 |
| Intervals larger than octaves | 29 |
| Intervals less than octaves | 27 |
| Intervals on a sounding line | 28 |
| Intervened officiously | 22 |
| Intervention group mantra | 25 |
| Interview after a mission | 25 |
| Interview near an inn? | 22 |
| Interview the god of war? | 25 |
| Interview wear, perhaps | 23 |
| Interview with news reporters | 29 |
| Interview with the IRS? | 23 |
| Interviewee on Mt. Sinai | 24 |
| Interviewee's worry | 23 |
| Interviewer's activity | 26 |
| Interviewer's booby trap | 28 |
| Interviewer's inaccuracy | 28 |
| Interviewer's invitation | 28 |
| Interviewer's surprises | 27 |
| Intestinal obstruction | 22 |
| Intestinal tract division | 25 |
| Intestinal wall projections | 27 |
| Intestine, in combinations | 26 |
| Intimate apparel purchase | 25 |
| Intimate email sign-off | 23 |
| Intimate email signoff | 22 |
| Intimate inn, familiarly | 24 |
| Intimate letter sign-off | 24 |
| Intimate modern message | 23 |
| Intimate term of address | 24 |
| Intimate wear, informally | 25 |
| Intimidate author Saul? | 23 |
| Intimidate with a fixed look | 28 |
| Intimidate, as a feline | 23 |
| Intimidated ballplayer? | 23 |
| Intimidating expression | 23 |
| Intimidating type of talk | 25 |
| Intimidating, as a task | 23 |
| Intimidation conclusion | 23 |
| Intl. acronym since 1960 | 24 |
| Intl. agreement since 1993 | 26 |
| Intl. alliance formed in 1948 | 29 |
| Intl. alliance since 1949 | 25 |
| Intl. assn. created in 1948 | 27 |
| Intl. assn. for learning | 24 |
| Intl. assn. since 1948 | 22 |
| Intl. association since 1960 | 28 |
| Intl. broadcasting initials | 27 |
| Intl. carrier to Seoul | 22 |
| Intl. cartel since 1960 | 23 |
| Intl. conflict of 1939-45 | 25 |
| Intl. defense alliance | 22 |
| Intl. disease-tracking grp. | 27 |
| Intl. economic coalition | 24 |
| Intl. group since 1948 | 22 |
| Intl. group since 1949 | 22 |
| Intl. group with 35 members | 27 |
| Intl. grp. from 1954-77 | 23 |
| Intl. humanities agcy. | 22 |
| Intl. humanities group | 22 |
| Intl. org. begun in 1958 | 24 |
| Intl. org. dismantled in 1977 | 29 |
| Intl. org. for young ones | 25 |
| Intl. Peace Garden state | 24 |
| Intl. peacekeeping gp. | 22 |
| Intl. price-setting group | 25 |
| Intl. signal adopted in 1912 | 28 |
| Intl. soccer powerhouse | 23 |
| Into a state of decline | 23 |
| Into anyone, potentially | 24 |
| Into cosplay, probably | 22 |
| Into mixed media, maybe | 23 |
| Into role-playing, perhaps | 26 |
| Into something quite a way | 26 |
| Into the Woods role | 22 |
| Into underground stuff | 22 |
| Into very small pieces | 22 |
| Into-the-stands homer, say | 26 |
| Intoxicant discussed online? | 28 |
| Intoxicating agent: Abbr. | 25 |