| ___ Snide (rock band) | 21 |
| ___ Snider, frontman for rock's Twisted Sister | 50 |
| ___ snit (peeved) | 17 |
| ___ Snooks | 10 |
| ___ Snorkel | 11 |
| ___ Snorkel of the funnies | 26 |
| ___ snow | 8 |
| ___ Snow, Russell Brand's character in "Forgetting Sarah Marshall" and "Get Him to the Greek" | 117 |
| ___ snuff | 9 |
| ___ snuff (adequate) | 20 |
| ___ snuff (O.K.) | 16 |
| ___ snuff (satisfactory) | 24 |
| ___ so | 6 |
| ___ so forth | 12 |
| ___ so good | 11 |
| ___ so happens | 14 |
| ___ so weiter (et cetera): Ger. | 31 |
| ___ soap (bath need) | 20 |
| ___ society | 11 |
| ___ Society (English debating group) | 36 |
| ___ Society (super-high I.Q. group) | 35 |
| ___ Society of Iowa | 19 |
| ___ Society, Iowa sect | 22 |
| ___ socks | 9 |
| ___ soda | 8 |
| ___ soda (acid neutralizer) | 27 |
| ___ soda (cleansing compound) | 29 |
| ___ soda (sodium carbonate) | 27 |
| ___ soda (textile bleacher) | 27 |
| ___ Soetoro (Obama's stepfather) | 36 |
| ___ Soft (major video game developer, once) | 43 |
| ___ soi (at home): Fr. | 22 |
| ___ soit qui mal y pense | 24 |
| ___ soit qui mal y pense (classic motto) | 40 |
| ___ soit qui mal y pense (old motto) | 36 |
| ___ Sol, part of sunny Spain | 28 |
| ___ soldier | 11 |
| ___ sole (single woman) | 23 |
| ___ Soleil | 10 |
| ___ Soleil (Louis XIV) | 22 |
| ___ Solo | 8 |
| ___ Solo ("Star Wars" character) | 42 |
| ___ Solo (character played by Peter Griffin on "Family Guy") | 70 |
| ___ Solo (Ford role) | 20 |
| ___ Solo (Harrison Ford role) | 29 |
| ___ Solo of "Star Wars" | 33 |
| ___ Solo, Harrison Ford role | 28 |
| ___ solution (contact lens wash) | 32 |
| ___ someone's eyes (deceive) | 32 |
| ___ son | 7 |
| ___ song | 8 |
| ___ song (caroled) | 18 |
| ___ song (cheaply) | 18 |
| ___ song (farewell appearance) | 30 |
| ___ song (inexpensively) | 24 |
| ___ songs | 9 |
| ___ sont | 8 |
| ___ Sophia (Istanbul landmark) | 30 |
| ___ Sophia, church built by Justinian | 37 |
| ___ soprano | 11 |
| ___ Sorensen, "Kennedy" author | 40 |
| ___ Sorrel (woman in a love triangle in "Adam Bede") | 62 |
| ___ sorry | 9 |
| ___ sort | 8 |
| ___ sort (in some respects) | 27 |
| ___ souci | 9 |
| ___ souci (carefree) | 20 |
| ___ souci (free from worry) | 27 |
| ___ soul (contract with Satan) | 30 |
| ___ Soul (hip-hop group) | 24 |
| ___ soul (no one) | 17 |
| ___ soul (nobody) | 17 |
| ___ Souls College, Oxford | 25 |
| ___ Sound | 9 |
| ___ Sound (Washington estuarine system) | 39 |
| ___ Sound Machine | 17 |
| ___ Sound, Fla. | 15 |
| ___ Sound, Fla. resort | 22 |
| ___ Sound, Wash. | 16 |
| ___ Sound, Washington | 21 |
| ___ Soundsystem | 15 |
| ___ Soundsystem (band with the 2010 album "This Is Happening") | 72 |
| ___ Soundsystem (subject of the 2012 documentary "Shut Up and Play the Hits") | 87 |
| ___ soup | 8 |
| ___ soup (Charleston dish) | 26 |
| ___ soup (Chinese favorite) | 27 |
| ___ soup (dense fog) | 20 |
| ___ soup (fog) | 14 |
| ___ soup (heavy fog) | 20 |
| ___ soup (Laotian delicacy) | 27 |
| ___ soup (starter at a Japanese restaurant) | 43 |
| ___ soup (sushi starter) | 24 |
| ___ soup to nuts (everything) | 29 |
| ___ Sousé (W.C. Fields in "The Bank Dick") | 55 |
| ___ South | 9 |
| ___ Southwest Grill (restaurant chain) | 38 |
| ___ space | 9 |
| ___ Space Holiday | 17 |
| ___ Spade (handbag company) | 27 |
| ___ spade a spade | 17 |