| ___ salts (foot-soaking stuff) | 30 |
| ___ salts (medicinal cathartic) | 31 |
| ___ Salty's (potato chip brand) | 35 |
| ___ salute (greets, in a way) | 29 |
| ___ salva (without risk): It. | 29 |
| ___ Salvador | 12 |
| ___ Salvador, El Salvador | 25 |
| ___ Sam | 7 |
| ___ Sam (card game) | 19 |
| ___ same mind | 13 |
| ___ sample | 10 |
| ___ San Lucas | 13 |
| ___ San Lucas (Baja resort) | 27 |
| ___ San Lucas, Baja Calif. | 26 |
| ___ San Lucas, Mexico | 21 |
| ___ sanction | 12 |
| ___ Sanctorum | 13 |
| ___ sanctum | 11 |
| ___ Sandman of song | 19 |
| ___ sandwich | 12 |
| ___ sang (Asian salad) | 22 |
| ___ sang (raw fish salad) | 25 |
| ___ Sanskrit | 12 |
| ___ Sant'Gria (wine brand) | 30 |
| ___ Sant'Gria (wine choice) | 31 |
| ___ Sant'Gria (wine) | 24 |
| ___ Santa | 9 |
| ___ Santa (basilica door) | 25 |
| ___ santé | 12 |
| ___ santé (French toast) | 27 |
| ___ Santiago, 1987 N.L. Rookie of the Year | 42 |
| ___ Santo | 9 |
| ___ Santo (E. Brazilian state) | 30 |
| ___ Santos | 10 |
| ___ Sap, Cambodian lake | 23 |
| ___ sapiens | 11 |
| ___ sapiens (humankind) | 23 |
| ___ Sarah Siddons | 17 |
| ___ Sark | 8 |
| ___ Sark, a Channel Islands ruler | 33 |
| ___ Sarto (Italian painter) | 27 |
| ___ sassy | 9 |
| ___ Satan (brat) | 16 |
| ___ Satay (Thai pork meal) | 26 |
| ___ satisfaction (be thwarted) | 30 |
| ___ sativa (the oat) | 20 |
| ___ sauce | 9 |
| ___ sauce (dessert topper) | 26 |
| ___ sauce (raspberry dessert topping) | 37 |
| ___ sauce (seafood condiment) | 29 |
| ___ sauce (sugary purée) | 27 |
| ___ Saud | 8 |
| ___ Saud (former Mideast leader) | 32 |
| ___ Saud (former Saudi king) | 28 |
| ___ Saud (Saudi Arabia's founder) | 37 |
| ___ Saud, founder of Saudi Arabia | 33 |
| ___ Sauer | 9 |
| ___ Sauer handguns | 18 |
| ___ Sauk Mountain, Mo. | 22 |
| ___ sausage | 11 |
| ___ Savage, player of the boy on "Boy Meets World" | 60 |
| ___ Savahl (couture label) | 26 |
| ___ Savy Fav (New York City indie band) | 39 |
| ___ saw (carpenter's curve cutter) | 38 |
| ___ Sawyer | 10 |
| ___ sax | 7 |
| ___ sax (low wind) | 18 |
| ___ saxophone | 13 |
| ___ say | 7 |
| ___ say (seemingly) | 19 |
| ___ say (unfortunate) | 21 |
| ___ say (unfortunately) | 23 |
| ___ say die | 11 |
| ___ Says (child's game) | 27 |
| ___ Says (kids' game) | 25 |
| ___ says (tots' game) | 25 |
| ___ Says! (dog treats) | 22 |
| ___ Sánchez, co-director of "The Blair Witch Project" | 66 |
| ___ scale | 9 |
| ___ scale (earthquake measurer) | 31 |
| ___ scale (hardness measure) | 28 |
| ___ scale (mineral hardness measure) | 36 |
| ___ scale of mineral hardness | 29 |
| ___ scallopini | 14 |
| ___ scaloppine | 14 |
| ___ scaloppini | 14 |
| ___ Scamander, pseudonym of J. K. Rowling | 41 |
| ___ scampi | 10 |
| ___ scan | 8 |
| ___ scan (biometric authentication method) | 42 |
| ___ scan (diagnostic aid) | 25 |
| ___ scarum | 10 |
| ___ sch. | 8 |
| ___ Schary | 10 |
| ___ scheme | 10 |
| ___ scheme (eponymous investment scam) | 38 |
| ___ scheme (investment fraud) | 29 |
| ___ scheme (investment scam) | 28 |
| ___ scheme (investment swindle) | 31 |
| ___ Schneider, villainess in "Indiana Jones and the Last Crusade" | 75 |