| ___ Iowa, Mississippi feeder | 28 |
| ___ ipsa loquitur | 17 |
| ___ ipsa loquitur (the thing speaks for itself) | 47 |
| ___ ipsum (faux-Latin phrase frequently used by publishers in placeholder text blocks) | 86 |
| ___ Irae | 8 |
| ___ iris (Spanish for "rainbow") | 42 |
| ___ Irish Cream | 15 |
| ___ iron | 8 |
| ___ Iron Range (Minnesota) | 26 |
| ___ irregular basis | 19 |
| ___ Irvan, 1991 winner at Daytona Beach | 39 |
| ___ Irvin, classic artist for The New Yorker | 44 |
| ___ Irvin, classic cartoonist | 29 |
| ___ Irvin, longtime cartoonist for The New Yorker | 49 |
| ___ Irvin, who designed the first cover for The New Yorker | 58 |
| ___ is cast | 11 |
| ___ is human | 12 |
| ___ is to say | 13 |
| ___ is! | 7 |
| ___ Isaacs Menken of stage fame | 31 |
| ___ Ishii ("Kill Bill" character) | 43 |
| ___ Ishii, character in "Kill Bill" | 45 |
| ___ Islam | 9 |
| ___ Island | 10 |
| ___ Island ("Jaws" resort) | 36 |
| ___ Island ("Survivor" locale) | 40 |
| ___ Island (Brooklyn peninsula) | 31 |
| ___ Island (former immigration checkpoint) | 42 |
| ___ Island (immigrants' arrival point) | 42 |
| ___ Island (immigrants' site) | 33 |
| ___ Island (immigrants' spot) | 33 |
| ___ Island (immigration point) | 30 |
| ___ Island (industrial area of Detroit) | 39 |
| ___ Island (location near Portland, Maine) | 42 |
| ___ Island (lonely place on "Survivor") | 49 |
| ___ Island (museum site) | 24 |
| ___ Island (NYC borough) | 24 |
| ___ Island (onetime immigrants' arrival point) | 50 |
| ___ Island (prison site) | 24 |
| ___ Island (Puget Sound locale) | 31 |
| ___ Island (site of a New York prison) | 38 |
| ___ Island (site of New York City's largest jail facility) | 62 |
| ___ Island Ferry | 16 |
| ___ Island in the Pacific | 25 |
| ___ Island National Monument | 28 |
| ___ Island National Wildlife Refuge, in Florida | 47 |
| ___ Island Red | 14 |
| ___ Island Red (chicken breed) | 30 |
| ___ Island Red (chicken) | 24 |
| ___ Island Sound | 16 |
| ___ Island, Bahamas, boyhood home of 47A | 40 |
| ___ Island, birthplace and longtime home of Cornelius Vanderbilt | 64 |
| ___ Island, Calif. | 18 |
| ___ Island, Canada | 18 |
| ___ Island, Casco Bay locale | 28 |
| ___ Island, discovery of Sunday, April 5, 1722 | 46 |
| ___ Island, Fla. | 16 |
| ___ Island, Florida | 19 |
| ___ Island, home for part of the Gateway National Recreation Area | 65 |
| ___ Island, immigrants' arrival point | 41 |
| ___ Island, in Antarctica | 25 |
| ___ Island, in San Francisco Bay | 32 |
| ___ Island, museum site since 1990 | 34 |
| ___ Island, N.C. | 16 |
| ___ Island, N.Y. | 16 |
| ___ Island, N.Y.C. | 18 |
| ___ Island, New York | 20 |
| ___ Island, off NW Ireland | 26 |
| ___ Island, Puerto Rico | 23 |
| ___ Island, site of a U.S. navy yard | 36 |
| ___ Island, U.S.M.A. training base | 34 |
| ___ Islands | 11 |
| ___ Islands (after translation, "Boar Island Islands") | 64 |
| ___ Islands (Attu et al.) | 25 |
| ___ Islands (British territory near Cuba) | 41 |
| ___ Islands (Caribbean country) | 31 |
| ___ Islands (Danish chain) | 26 |
| ___ Islands (Guam's group) | 30 |
| ___ Islands (Java, Borneo, etc.) | 32 |
| ___ Islands (part of the Aleutians) | 35 |
| ___ Islands (Scapa Flow locale) | 31 |
| ___ Islands (supposed site of the Fountain of Youth) | 52 |
| ___ Islands (the Bermudas' former name) | 43 |
| ___ Islands in Galway Bay | 25 |
| ___ Islands in the Bahamas | 26 |
| ___ Islands of Denmark | 22 |
| ___ Islands of Galway Bay | 25 |
| ___ Islands of Indonesia | 24 |
| ___ Islands off Galway | 22 |
| ___ Islands off N Australia | 27 |
| ___ Islands off Sicily | 22 |
| ___ Islands off the Irish coast | 31 |
| ___ Islands, between Scotland and Iceland | 41 |
| ___ Islands, bird sanctuary | 27 |
| ___ Islands, Blackbeard's base | 34 |
| ___ Islands, east of Miami | 26 |
| ___ Islands, former name of Belau | 33 |
| ___ Islands, Galway Bay | 23 |
| ___ Islands, group at the mouth of Galway Bay | 45 |
| ___ Islands, in Bay of Bengal | 29 |