| ___ Dee, Carolina river | 23 |
| ___ Dee, river in the Carolinas | 31 |
| ___ Dee, southern river | 23 |
| ___ deed (Monopoly card) | 24 |
| ___ deep | 8 |
| ___ Deep (hip-hop duo) | 22 |
| ___ Deep (oceanic depression) | 29 |
| ___ deep (over-involved) | 24 |
| ___ Deep, depression near Guam | 30 |
| ___ Deep, oceanic depression | 28 |
| ___ deer | 8 |
| ___ Def | 7 |
| ___ Def (erstwhile hip-hop name) | 32 |
| ___ Def (rapper Yasiin Bey's former stage name) | 51 |
| ___ Defarge of "A Tale of Two Cities" | 47 |
| ___ Defense (chess opening named after an Eastern European) | 59 |
| ___ defense (chess opening) | 27 |
| ___ defense (tactic to prevent a hostile takeover) | 50 |
| ___ deferens | 12 |
| ___ deficit (lost money) | 24 |
| ___ degree | 10 |
| ___ Dehuai of China | 19 |
| ___ Dei | 7 |
| ___ Dei ("The Da Vinci Code" group) | 45 |
| ___ Dei, organization in "The Da Vinci Code" | 54 |
| ___ del Carmen, Mexico | 22 |
| ___ del Castillo, Cortés's historian | 43 |
| ___ del Corso, Rome | 19 |
| ___ del Este | 12 |
| ___ del Este, Uruguay | 21 |
| ___ del Fuego | 13 |
| ___ del Giocondo (subject of a da Vinci portrait) | 49 |
| ___ del mar (arrow crab) | 24 |
| ___ del Mar, Chile | 18 |
| ___ del mono (Spanish liqueur) | 30 |
| ___ del Norte (Rio Grande gorge) | 32 |
| ___ del Plata (Argentine port) | 30 |
| ___ del Plata (Argentinean resort) | 34 |
| ___ del Plata, Argentina | 24 |
| ___ Del Rey | 11 |
| ___ del Rey, Calif. | 19 |
| ___ del Rio (''Macarena'' group) | 48 |
| ___ del Rio ("Macarena" singers) | 42 |
| ___ del Rio, Cuba | 17 |
| ___ del Rio, in SW Spain | 24 |
| ___ del Rio, Sevilla suburb | 27 |
| ___ del Rio, town near Sevilla | 30 |
| ___ del Sol | 11 |
| ___ del Sol (region in Spain) | 29 |
| ___ del Sol, 1982 Derby winner | 30 |
| ___ del Sol, Derby winner: 1982 | 31 |
| ___ del Sol, Spain | 18 |
| ___ del Sur (South Sea) | 23 |
| ___ del Tomba, possible rocker retreat | 38 |
| ___ del Vaticano | 16 |
| ___ Delacroix ("The Green Mile" protagonist) | 54 |
| ___ Delano Roosevelt | 20 |
| ___ delegation | 14 |
| ___ Delgada, E Azores | 21 |
| ___ Delgada, Portuguese port | 28 |
| ___ Delgado (special agent on "Without a Trace") | 58 |
| ___ Delhi | 9 |
| ___ Delicious | 13 |
| ___ delight (card game) | 23 |
| ___ delight (solitaire game) | 28 |
| ___ della Francesca, famed Italian artist | 41 |
| ___ Deluxe (old McDonald's sandwich) | 40 |
| ___ Demolition Night (record-breaking 1979 White Sox promotion) | 63 |
| ___ den Linden | 14 |
| ___ den Linden (Berlin boulevard) | 33 |
| ___ den Linden, Berlin | 22 |
| ___ denied (Supreme Court phrase) | 33 |
| ___ denied (Supreme Ct. phrase) | 31 |
| ___ Deo | 7 |
| ___ Department | 14 |
| ___ Deportes (Spanish-language channel) | 39 |
| ___ depth finder | 16 |
| ___ derby | 9 |
| ___ Derby (mottled green cheese) | 32 |
| ___ Derby, annual sporting event since 1866 | 43 |
| ___ deriva (Adrift, in Spanish) | 31 |
| ___ des Beaux-Arts | 18 |
| ___ des Beaux-Arts, in Paris | 28 |
| ___ des Beaux-Arts, Paris | 25 |
| ___ Desert | 10 |
| ___ Desert (after translation, "Desert Desert") | 57 |
| ___ Desert (area with saguaros) | 31 |
| ___ desk | 8 |
| ___ desk (newsroom assignment) | 30 |
| ___ Desmond, "Sunset Boulevard" diva | 46 |
| ___ desperandum | 15 |
| ___ Dessert Pizza (Domino's dish) | 37 |
| ___ detachment | 14 |
| ___ details | 11 |
| ___ Detective (1930's-50's crime fiction magazine) | 58 |
| ___ detector (polygraph) | 24 |
| ___ detergent | 13 |
| ___ Detoo | 9 |
| ___ Detoo of "Star Wars" | 34 |
| ___ Detoo, "Star Wars" android | 40 |