| What Salk vaccine prevents | 26 |
| What salmon do | 14 |
| What salmon do upriver | 22 |
| What salmon seek to do | 22 |
| What salt may be used as | 24 |
| What Sam Goldwyn said to "include me in" | 50 |
| What Sam made too long | 22 |
| What Sam plays in "Casablanca" | 40 |
| What Sam twitched on "Bewitched" | 42 |
| What Samantha twitched on "Bewitched" | 47 |
| What Sampras does? | 18 |
| What Sandburg called "a bucket of ashes" | 50 |
| What Sandy says | 15 |
| What Santa checks twice | 23 |
| What Santa Claus is | 19 |
| What Santa gets for climbing down the chimney? | 46 |
| What Santa is not | 17 |
| What Santa makes | 16 |
| What Santa's doing | 22 |
| What Santa's elves rode when the sleigh broke down? | 55 |
| What Santa's mail consists of | 33 |
| What Santa's making (and checking twice) | 44 |
| What Santa's reindeer shouted out with? | 43 |
| What Santana was doing on '81 hit | 37 |
| What santé means | 19 |
| What Sartre said? | 17 |
| What SASEs are | 14 |
| What sassafras has a lot of? | 28 |
| What Satan asked | 16 |
| What Satan gets from poison ivy? | 32 |
| What Satan sows | 15 |
| What Satchmo said to Dolly | 26 |
| What satiety sans variety breeds | 32 |
| What sauerkraut ferments in | 27 |
| What saunas feature | 19 |
| What savants are steeped in | 27 |
| What savers do with money | 25 |
| What say? | 9 |
| What says "Miss America" on Miss America | 50 |
| What scammers practice | 22 |
| What Scarlett did? | 18 |
| What scattered things are said to be all over | 45 |
| What schlimazels usually do | 27 |
| What schools have | 17 |
| What schools in the same district have, often | 45 |
| What Schwarzenegger pumps | 25 |
| What sci-fi heroes must combat | 30 |
| What science fiction movie do taxes and amine bring to mind? | 60 |
| What science fiction writers do | 31 |
| What scientists use to predict the rates of chemical reactions | 62 |
| What scientists working for Gatorade have? | 42 |
| What Scopes taught | 18 |
| What Scots speak | 16 |
| What scouts pitch | 17 |
| What Scoville units measure | 27 |
| What scratch-and-sniff stickers emit | 36 |
| What screaming may exacerbate | 29 |
| What Scrooge learned to do | 26 |
| What scuff marks show | 21 |
| What sculptors do | 17 |
| What seagulls come in? | 22 |
| What seamstress does to stage garb | 34 |
| What seas do to shores | 22 |
| What seatbelts save | 19 |
| What second place at battle of the bands does | 45 |
| What second-story men do | 24 |
| What secondary recipients of e-mails get | 40 |
| What secrets did ___? | 21 |
| What secrets might be kept on | 29 |
| What security did when you hopped the fence | 43 |
| What security does to fence-hopper | 34 |
| What security will do to sneaker-upper | 38 |
| What seeds are often planted in | 31 |
| What seeds may be found in | 26 |
| What seems like forever | 23 |
| What seers have | 15 |
| What selfish individuals have? | 30 |
| What sells the steak | 20 |
| What semis do | 13 |
| What Sen. Dole does? | 20 |
| What Sen. Norris gave | 21 |
| What Senators represent | 23 |
| What Seneca spoke | 17 |
| What sentence components should do | 34 |
| What sentries must be on | 24 |
| What separates Romeo from Juliet? | 33 |
| What separates the lead singer from the band? | 45 |
| What September 23 marks | 23 |
| What serious players play for | 29 |
| What sets a straphanger on autopilot? | 37 |
| What settles | 12 |
| What severe cuts may result in, briefly | 39 |
| What sexy singer will do with audience | 38 |
| What Sgt. Friday sought | 23 |
| What Sgt. Friday wanted | 23 |
| What Sgt. Schultz really knew (but would never admit) on "Hogan's Heroes"? | 88 |
| What sgts. turn in at HQ's | 30 |
| What shad are prized for | 24 |
| What shady promoter won't take seriously | 44 |
| What shady promoters can't give | 35 |