| What nods signify | 17 |
| What Nolan Ryan became in 1979 | 30 |
| What Nolan Ryan does | 20 |
| What nomads do | 14 |
| What nomads hit? | 16 |
| What non-swimmers do | 20 |
| What non-ticket-holders do to gate | 34 |
| What none of the teams in this puzzle play | 42 |
| What nonparallel lines do eventually | 36 |
| What North and South Dakota do | 30 |
| What not even the richest person on Earth has | 45 |
| What not to call Bryn Mawr | 26 |
| What not to do before December 25? | 34 |
| What not to do to Superman's cape | 37 |
| What not to get from the boss | 29 |
| What not to get in | 18 |
| What not to rock | 16 |
| What not to rock or miss | 24 |
| What not to see, hear or speak | 30 |
| What not to sweat | 17 |
| What not to touch something with | 32 |
| What not to yell in a crowded theater | 37 |
| What notorious 1999 computer virus was named after an exotic dancer? | 68 |
| What nouns and verbs must do | 28 |
| What novices don't know | 27 |
| What Novocain creates | 21 |
| What NOW wants now | 18 |
| What NOW wants women to be | 26 |
| What nudity may lead to | 23 |
| What nudniks do | 15 |
| What numbers after some colons represent | 40 |
| What nuns take | 14 |
| What nut's from Tippecanoe? | 31 |
| What nyctophobes fear | 21 |
| What O may mean | 15 |
| What O'Hara's Joey was | 30 |
| What O'Neill called "Dat ole davil" | 49 |
| What O'Neill wields | 23 |
| What O. J. gains | 16 |
| What O.S. means in prescriptions for glasses | 44 |
| What Oasis stressed "The Importance of Being" | 55 |
| What Obama is called, often | 27 |
| What Obama was shooting in that one picture | 43 |
| What obfuscators lack | 21 |
| What obsolete things fall into | 30 |
| What occurs on a trip to the laundromat? | 40 |
| What ochlophobes fear | 21 |
| What ochlophobists fear | 23 |
| What octothorpes may represent | 30 |
| What odes do | 12 |
| What Oedipus solved | 19 |
| What often comes with a twist? | 30 |
| What often does it? | 19 |
| What often follows you | 22 |
| What often grows attached? | 26 |
| What ogles made the handsome butcher feel like? | 47 |
| What Oglethorpe's colonists had incurred | 44 |
| What ogres cause | 16 |
| What ogres do | 13 |
| What oil cleanups clean up | 26 |
| What oil helps dissolve | 23 |
| What old enemies may do | 23 |
| What Old Faithful blows off | 27 |
| What old grads do | 17 |
| What Old Mother Hubbard's dog got | 37 |
| What Old Mother Hubbard's dog had | 37 |
| What old rocker looks | 21 |
| What old soldiers do | 20 |
| What old stogies do | 19 |
| What old tires do | 17 |
| What old-timers need to get on stage, perhaps | 45 |
| What olden days were of | 23 |
| What older baseball pitchers might do? | 38 |
| What oldies evoke | 17 |
| What olfactometers measure | 26 |
| What Oliver asked for more of | 29 |
| What Oliver Twist wanted | 24 |
| What Oliver wanted | 18 |
| What Olympic bobsleds do | 24 |
| What one about to break the tape has | 36 |
| What one achieves by building stages for the pope? | 50 |
| What one achieves by smashing one's malfunctioning smartphone against a branch? | 83 |
| What one at the head of a line likes to hear | 44 |
| What one becomes in Madrid | 26 |
| What one beyond help may be called | 34 |
| What one can do, figuratively, to the last words of the four longest Across answers | 83 |
| What one can see | 16 |
| What one carries for parries | 28 |
| What one does for his own interest? | 35 |
| What one does to a joint? | 25 |
| What one doesn't pay at a clearance sale | 44 |
| What one dream said to the other dream? | 39 |
| What one gets by multiplying the numbers in this puzzle's theme answers | 75 |
| What one gets for buckets, in the NBA | 37 |
| What one gets from the hot dog vendor when paying with a $5 bill? | 65 |
| What one gets reading poetry? | 29 |
| What one has at the top | 23 |
| What one has while watching an Eastwood film? | 45 |
| What one hopes not to get off to, on a date | 43 |
| What one in control has | 23 |