| What an old comedian chomps | 27 |
| What an old sci-fi comics fan might see? | 40 |
| What an old yearbook may elicit | 31 |
| What an old-timer may be called | 31 |
| What an oneirocritic interprets | 31 |
| What an onion may produce | 25 |
| What an onychophagist bites | 27 |
| What an oozy thing might ooze | 29 |
| What an ophthalmologist does | 28 |
| What an optimist always has | 27 |
| What an optimist always looks on | 32 |
| What an optimist envisions | 26 |
| What an optimist has | 20 |
| What an optometrist at a kindergarten examines? | 47 |
| What an orchestra tunes to | 26 |
| What an orchestral trapper can do | 33 |
| What an orthodontist works on | 29 |
| What an ostiary guards | 22 |
| What an otoscope explores | 25 |
| What an out patient may be in | 29 |
| What an out patient may be in? | 30 |
| What an out-turned palm may mean | 32 |
| What an outfielder does for practice | 36 |
| What an outstanding witness provides | 36 |
| What an outturned palm may mean | 31 |
| What an ovate fellow did in a rhyme | 35 |
| What an overloaded bookshelf does | 33 |
| What an R.N. administers | 24 |
| What an R.N. gives | 18 |
| What an R.N. might take | 23 |
| What an R.N. provides | 21 |
| What an R.N. takes | 18 |
| What an RN dispenses | 20 |
| What an RN supplies | 19 |
| What an SRO sign might portend | 30 |
| What an umbrella may provide | 28 |
| What an ump's protector protects | 36 |
| What an umpire makes | 20 |
| What an umpire's indicator indicates | 40 |
| What an unappealing offer might get | 35 |
| What an underline might indicate | 32 |
| What an underwater gunner can do | 32 |
| What an unemployed person hunts for | 35 |
| What an unevenly milked cow might have? | 39 |
| What an unrequited lover carries | 32 |
| What an unwavering hero in westerns does | 40 |
| What an up-and-coming band wants to snag | 40 |
| What an urban maid may watch | 28 |
| What an usher will do | 21 |
| What an X may indicate | 22 |
| What an X-Acto knife might make | 31 |
| What an XXXL jacket is, for many | 32 |
| What analgesics are to pain | 27 |
| What anarchies lack | 19 |
| What anatomists call "axilla" | 39 |
| What anchors engender | 21 |
| What anchors face | 17 |
| What ancient warships were built to do | 38 |
| What andirons support | 21 |
| What Andrew Jackson Jihad is "Brave As" | 49 |
| What androphobes fear | 21 |
| What Andy Capp uses to buy ale? | 31 |
| What Andy Capp's bartender serves him? | 42 |
| What angels count | 17 |
| What angels did during killer show | 34 |
| What anglers want that campers don't | 40 |
| What angry dogs do | 18 |
| What angry wasps might do to a room? | 36 |
| What animal bites may cause | 27 |
| What animal does a bulldogger throw? | 36 |
| What Ann might call Abby | 24 |
| What Anna's king would be today | 35 |
| What Annabel Lee's kingdom was by | 37 |
| What Anne Hathaway hath | 23 |
| What annoyers do | 16 |
| What anosmic people can't sense | 35 |
| What anosmic people do not sense | 32 |
| What anosmic people don't sense | 35 |
| What Antarctica is, technically | 31 |
| What anthrophobes prefer to be | 30 |
| What Antofalla might spew | 25 |
| What Antony borrowed | 20 |
| What Antony sought to borrow | 28 |
| What Antony wanted to borrow | 28 |
| What ants do | 12 |
| What anxiety provides | 21 |
| What any good story has | 23 |
| What any hit record does | 24 |
| What any horse needs to win the Preakness? | 42 |
| What any man, woman or child may break into | 43 |
| What any of the Four Horsemen symbolizes | 40 |
| What apartment dwellers have to pay | 35 |
| What apostrophes are often used for | 35 |
| What appears above a piñata? | 31 |
| What Apple's Project Purple became | 38 |
| What appreciative customers give a tailor thanks for? | 53 |
| What April has, unlike any other month? | 39 |
| What aquafortists do | 20 |
| What Aquarius holds | 19 |
| What aquatinters do | 19 |