| U.S. Presidency, in Jefferson's words | 41 |
| U.S. President | 14 |
| U.S. president #2 | 17 |
| U.S. president after Grant | 26 |
| U.S. president and also chief justice | 37 |
| U.S. president during the Mexican War | 37 |
| U.S. President who inaugurated baseball's 7th inning stretch, allegedly | 75 |
| U.S. president who sired 15 children | 36 |
| U.S. president whose mother's first name was Stanley | 56 |
| U.S. President William Howard | 29 |
| U.S. president's command | 28 |
| U.S. president's title | 26 |
| U.S. president, 1861 to 1865 | 28 |
| U.S. president, 1861-1865 | 25 |
| U.S. president, 1909-13 | 23 |
| U.S. president, at times | 24 |
| U.S. presidential campaigner's audience | 43 |
| U.S. Presidents | 15 |
| U.S. press org. | 15 |
| U.S. priest-poet John Banister ___ | 34 |
| U.S. priest-poet: 1845-1909 | 27 |
| U.S. prison org. | 16 |
| U.S. problem, according to J.E.C. | 33 |
| U.S. property manager | 21 |
| U.S. provider of Olympic coverage | 33 |
| U.S. psychologist Arnold ___ | 28 |
| U.S. psychologist-pediatrician | 30 |
| U.S. public health agcy. | 24 |
| U.S. publicans | 14 |
| U.S. publisher | 14 |
| U.S. publisher: 1858-1935 | 25 |
| U.S. publishing family | 22 |
| U.S. purchase of 1867 | 21 |
| U.S. Quaker leader | 18 |
| U.S. radio arm that broadcasts in Burmese, among other languages | 64 |
| U.S. radio service | 18 |
| U.S. radio station in Berlin | 28 |
| U.S. rail | 9 |
| U.S. rail service | 17 |
| U.S. railroad, for short | 24 |
| U.S. ranch bird, nowadays | 25 |
| U.S. real estate deal: 1853 | 27 |
| U.S. rebellion leader | 21 |
| U.S. rebellion leader of 1841-42 | 32 |
| U.S. rebellion leader of 1842 | 29 |
| U.S. reconnaissance satellite | 29 |
| U.S. reformer | 13 |
| U.S. region that's growing? | 31 |
| U.S. regulatory agcy. | 21 |
| U.S. regulatory board | 21 |
| U.S. regulatory org. since 1935 | 31 |
| U.S. research org. | 18 |
| U.S. research rocket | 20 |
| U.S. resident's peers | 25 |
| U.S. resort lake | 16 |
| U.S. retailer since 1902 | 24 |
| U.S. revolutionary Daniel ___ | 29 |
| U.S. rights defender | 20 |
| U.S. rights org. | 16 |
| U.S. river or state | 19 |
| U.S. rocket | 11 |
| U.S. rocket launched in 1961 | 28 |
| U.S. rocket stage | 17 |
| U.S. rocket with a name from classical myth | 43 |
| U.S. rocket with a name from Greek myth | 39 |
| U.S. Safeguard Program features | 31 |
| U.S. satellite | 14 |
| U.S. satellite of the '60s | 30 |
| U.S. savings certificate | 24 |
| U.S. scholastic org. | 20 |
| U.S. school near Juarez | 23 |
| U.S. scientific satellite of the 60's | 41 |
| U.S. sculptor | 13 |
| U.S. sculptor of 1800's | 27 |
| U.S. sculptor: 1898–1976 | 31 |
| U.S. sea arm | 12 |
| U.S. sea-rescue group | 21 |
| U.S. seaport founded in 1626 | 28 |
| U.S. Sec. of State: 1905-9 | 26 |
| U.S. Sec. of War: 1829-31 | 25 |
| U.S. Secretary of State (1961-1969) | 35 |
| U.S. secretary of state raised in the Bronx | 43 |
| U.S. secretary of state tied for the second-longest time in office | 66 |
| U.S. Secretary of State: 1898–1905 | 41 |
| U.S. security | 13 |
| U.S. Security investment | 24 |
| U.S. security offering | 22 |
| U.S. security, briefly | 22 |
| U.S. security, for short | 24 |
| U.S. Senate alumnus Sam | 23 |
| U.S. senator | 12 |
| U.S. Senator from N.C.: 1954-74 | 31 |
| U.S. senator with the longest tenure in history | 47 |
| U.S. senator's salary, e.g. | 31 |
| U.S. servicewoman | 17 |
| U.S. Shaker sect founder | 24 |
| U.S. ship transmuted | 20 |
| U.S. singer-actor | 17 |
| U.S. skater David ___ | 21 |
| U.S. sky eye | 12 |