| Its extract is used in Worcestershire sauce | 43 |
| Isn't likely to win any culinary awards | 43 |
| It could be a heart up someone's sleeve | 43 |
| Impetus for a 1773 Boston "party" | 43 |
| Iron-___ (brand of nutritional supplements) | 43 |
| It's often said before "said" | 43 |
| Indie/electronica group formed in Edinburgh | 43 |
| It's too important to ignore, literally | 43 |
| It could be represented by an "X" | 43 |
| It's needed while watching a tearjerker | 43 |
| It's frequently under a star's name | 43 |
| It's supportive for those eating in bed | 43 |
| It's usually smaller than a city: Abbr. | 43 |
| In other words, it'll break in 24 hours | 43 |
| Its license plates depict the Delicate Arch | 43 |
| It'll tell you which way the wind blows | 43 |
| Instrument popular in Shakespeare's day | 43 |
| It's good for absolutely nothing [hunh] | 43 |
| It's almost always actually horseradish | 43 |
| Instantaneous web-based communication syst. | 43 |
| It precedes Yankee in the phonetic alphabet | 43 |
| It's often posted at a freeway entrance | 43 |
| It's wasted on the young, it's said | 43 |
| It's nice when checks have lots of them | 43 |
| In Boston, this makes a god out of a guard | 42 |
| It's usually said with the eyes closed | 42 |
| It's leading a campaign to close Gitmo | 42 |
| It's what pride goeth before, they say | 42 |
| It might be said ahead of "said" | 42 |
| Irish actor Gillen of "The Wire" | 42 |
| Its State Quarter has Braille on it: Abbr. | 42 |
| It's more than twice the size of Texas | 42 |
| It gained independence from France in 1962 | 42 |
| Its hub is Leonardo da Vinci International | 42 |
| It may accompany waves on a Hawaiian beach | 42 |
| It's about 80 miles east of Pittsburgh | 42 |
| It's lost when one starts getting paid | 42 |
| It may follow "forever and ever" | 42 |
| Independent Presidential candidate of 1980 | 42 |
| Impossibles song "Erin With ___" | 42 |
| It goes before E except after C, sometimes | 42 |
| In respect to, with ''of'' | 42 |
| It can be calculated after taking a survey | 42 |
| Its crew was protected by the goddess Hera | 42 |
| Island north of the Paraguaná Peninsula | 42 |
| Island in the lyrics to "Kokomo" | 42 |
| It comes before Wednesday only once a year | 42 |
| Inability to distinguish different pitches | 42 |
| Isn't content with the status quo, say | 42 |
| Italian town on the slope of Mount Subasio | 42 |
| It's smashed in a particle accelerator | 42 |
| Illinois or Oriental, briefly, in Monopoly | 42 |
| It began as the California Perfume Company | 42 |
| Imaginary line about which the Earth turns | 42 |
| Items added to Norm Peterson's bar tab | 42 |
| It typically has a ribbon around its crown | 42 |
| It ceased to be a European capital in 1991 | 42 |
| It's also called a "way car" | 42 |
| Indian tribe for whom a large sea is named | 42 |
| Initials on a U.S.S.R. player's jersey | 42 |
| Increasingly quaint musical storage option | 42 |
| Instruments that are straddled when played | 42 |
| It's represented after a "." | 42 |
| Item of sports equipment worn on the wrist | 42 |
| It's returned after someone swipes it? | 42 |
| It's often squared, for a statistician | 42 |
| Irish county bordered by the river Shannon | 42 |
| It may accompany ''Ahem!'' | 42 |
| Indian tribe who fought in the War of 1812 | 42 |
| It's seen in the first or last quarter | 42 |
| Item with which Osiris is usually pictured | 42 |
| Inspiration for Dan Brown's 2013 novel | 42 |
| Impressionist Edgar who painted ballerinas | 42 |
| Indira Gandhi International Airport locale | 42 |
| It's in the center of a vegetable tray | 42 |
| It fled with the spoon, in a nursery rhyme | 42 |
| It's implicit in all knock-knock jokes | 42 |
| Is foolishly fond of (with "on") | 42 |
| Internet connection that postdated dial-up | 42 |
| It's "in the Wind" to Kansas | 42 |
| It usually occurs twice a day at the shore | 42 |
| It's written from the heart, for short | 42 |
| It's impacted by global warming: Abbr. | 42 |
| It shares the same keys as a G major scale | 42 |
| Insufferable, lovelorn and whiny, in slang | 42 |
| It's mellow and has a pear-shaped bell | 42 |
| In myth, her tears created the morning dew | 42 |
| It's hardly a cutting-edge competition | 42 |
| Illustrious relative of Mariel and Margaux | 42 |
| Important info for people with connections | 42 |
| Irving Stone's "Love Is ___" | 42 |
| Item for a woman's travel bag, perhaps | 42 |
| It holds about 70% of the world population | 42 |
| It's almost seven, but seven is not it | 42 |
| It follows the answer to each starred clue | 42 |
| Ivana and Marla, in relation to The Donald | 42 |
| In Texas, they're "upon you" | 42 |
| It's "in one era and . . . " | 42 |
| Iron and Wine "Resurrection ___" | 42 |
| Item for an exhaustive search, so to speak | 42 |