| A sib's published diaries? | 30 |
| A sibling | 9 |
| A sibling of Cottontail | 23 |
| A sibling of Zeppo | 18 |
| A sick bird? | 12 |
| A sickening amount of Mr. Bradley? | 34 |
| A side dish | 11 |
| A side of Manhattan | 19 |
| A side of N.Y.C. | 16 |
| A side of New York | 18 |
| A side of the Admirable Doctor? | 31 |
| A side of the Big Apple | 23 |
| A Sierra Nevada pass | 20 |
| A sigh | 6 |
| A sighed aside | 14 |
| A sight at Abu Simbel | 21 |
| A sight for sore ___ | 20 |
| A sight for ___ eyes | 20 |
| A sight in suburbia | 19 |
| A sight ___ | 11 |
| A sign from above | 17 |
| A sign of a kind | 16 |
| A sign of August | 16 |
| A sign of elation or optimism | 29 |
| A sign of spring | 16 |
| A sign of sugar | 15 |
| A sign of summer | 16 |
| A sign of the times? | 20 |
| A sign of the zodiac | 20 |
| A sign of things to come | 24 |
| A signal horn | 13 |
| A silent bid | 12 |
| A silent butler may hold it | 27 |
| A silk hat brought him to life | 30 |
| A silverfish | 12 |
| A simple job | 12 |
| A simple machine | 16 |
| A simpler one may be recalled | 29 |
| A Simpson | 9 |
| A Simpson sister | 16 |
| A Simpson without access to his volume of the "Odyssey"? | 66 |
| A Sinatra | 9 |
| A singer | 8 |
| A singing Boone | 15 |
| A singing Ford | 14 |
| A singing group | 15 |
| A singing Guthrie | 17 |
| A singing Horne | 15 |
| A singing Jackson | 17 |
| A single | 8 |
| A single bite | 13 |
| A single bounce, in baseball | 28 |
| A single cent | 13 |
| A single is one | 15 |
| A single may get you one, briefly | 33 |
| A single may go this | 20 |
| A single might get you one | 26 |
| A single might get you one: Abbr. | 33 |
| A single occasion | 17 |
| A single stroke | 15 |
| A single stroke under par | 25 |
| A single time | 13 |
| A single, in Stuttgart | 22 |
| A sinsation | 11 |
| A Siouan | 8 |
| A sir | 5 |
| A Sis or a Bro | 14 |
| A sister of Ares | 16 |
| A sister of Calliope | 20 |
| A sister of Clio | 16 |
| A sister of Cordelia | 20 |
| A sister of Demeter | 19 |
| A sister of Eunomia | 19 |
| A sister of Europa | 18 |
| A sister of Goneril | 19 |
| A sister of John Boy | 20 |
| A sister of Jupiter | 19 |
| A sister of Melpomene | 21 |
| A sister of Peter Rabbit | 24 |
| A sister of Pygmalion | 21 |
| A sister of Semele | 18 |
| A sister of Terpsichore | 23 |
| A sister of Thalia | 18 |
| A sister of Zsa Zsa | 19 |
| A sister-in-law of Albany | 25 |
| A sister-in-law of Jacob | 24 |
| A site of the Normandy Invasion | 31 |
| A sitter employs one | 20 |
| A Sitwell | 9 |
| A sixth of the way through the hour | 35 |
| A sixth-century Dacia settler | 29 |
| A sixth-day creation | 20 |
| A size | 6 |
| A size of larceny | 17 |
| A size of paper | 15 |
| A size smaller, say | 19 |
| A size too small | 16 |
| A size too small, maybe | 23 |
| A skein of _____ | 16 |
| A skin layer | 12 |