| U.S. philanthropist:1867–1933 | 36 |
| U.S. pharmaceuticals regulator | 30 |
| U.S. pharmaceuticals overseer | 29 |
| U.S. petroleum center | 21 |
| U.S. pet protector | 18 |
| U.S. perennial herb | 19 |
| U.S. pension org. | 17 |
| U.S. penologist | 15 |
| U.S. patriotic display | 22 |
| U.S. patriot | 12 |
| U.S. Park Service employee | 26 |
| U.S. painting family | 20 |
| U.S. painter: 1871–1951 | 30 |
| U.S. painter: 1871-1951 | 23 |
| U.S. painter: 1859–1940 | 30 |
| U.S. painter: 1844–1916 | 30 |
| U.S. painter-sculptor: 1869-1953 | 32 |
| U.S. painter-etcher-illustrator | 31 |
| U.S. painter Robert | 19 |
| U.S. painter Rembrandt | 22 |
| U.S. painter Mark ___: 1890-1976 | 32 |
| U.S. painter Leon | 17 |
| U.S. painter John ___: 1871-1951 | 32 |
| U.S. painter George | 19 |
| U.S. painter and family | 23 |
| U.S. painter Alex ___ | 21 |
| U.S. painter | 12 |
| U.S. Pacific territory | 22 |
| U.S. Pacific island | 19 |
| U.S. overseas radio agcy. | 25 |
| U.S. output measure | 19 |
| U.S. output | 11 |
| U.S. outlaw | 11 |
| U.S. org. with over 39 million members | 38 |
| U.S. org. for minor traders | 27 |
| U.S. orator and family | 22 |
| U.S. orator | 11 |
| U.S. or English poet | 20 |
| U.S. or Can. money | 18 |
| U.S. or British mil. award | 26 |
| U.S. operative | 14 |
| U.S. Open, e.g. | 15 |
| U.S. Open's ___ Stadium | 27 |
| U.S. Open winner: 1977 | 22 |
| U.S. Open winner: 1976 | 22 |
| U.S. Open winner: 1961 | 22 |
| U.S. Open winner: 1934 | 22 |
| U.S. Open winner, 1994 and 1997 | 31 |
| U.S. Open winner of 1994 and 1997 | 33 |
| U.S. Open winner in 1997 | 24 |
| U.S. Open winner from Argentina | 31 |
| U.S. Open winner Els | 20 |
| U.S. Open units | 15 |
| U.S. Open tennis victor over Arthur: 1972 | 41 |
| U.S. Open tennis stadium | 24 |
| U.S. Open tennis finalist eight straight years | 46 |
| U.S. Open tennis champ: 1968 | 28 |
| U.S. Open tennis champ: 1966 | 28 |
| U.S. Open tennis champ: 1963 | 28 |
| U.S. Open stadium name | 22 |
| U.S. Open stadium | 17 |
| U.S. Open singles champ: 1972 | 29 |
| U.S. Open players, usually | 26 |
| U.S. Open park, for short | 25 |
| U.S. Open org. | 14 |
| U.S. Open judge's shout | 27 |
| U.S. Open golf champion Ernie | 29 |
| U.S. Open golf champ: 1988-89 | 29 |
| U.S. Open golf champ: 1959 | 26 |
| U.S. Open golf champ: 1927 | 26 |
| U.S. Open entrant | 17 |
| U.S. Open do-over | 17 |
| U.S. Open component | 19 |
| U.S. Open champion: 1968 | 24 |
| U.S. Open champion whose last name is a toy | 43 |
| U.S. Open champ: 1976 | 21 |
| U.S. Open champ, Arthur | 23 |
| U.S. Open champ, 1985-87 | 24 |
| U.S. Open champ, 1968 | 21 |
| U.S. Open champ Tony: 1936 | 26 |
| U.S. Open champ in '94 and '97 | 38 |
| U.S. Open champ Ernie | 21 |
| U.S. Open champ before and after Pete | 37 |
| U.S. Open category | 18 |
| U.S. Olympic swimming gold medalist Torres | 42 |
| U.S. Olympic skier | 18 |
| U.S. Olympic gymnast Chow | 25 |
| U.S. Olympic diver Louganis | 27 |
| U.S. Olympic champion, 1956 | 27 |
| U.S. Olympic and welterweight champ | 35 |
| U.S. oil giant | 14 |
| U.S. official whose office has been vacant for more than nine of the last 50 years | 82 |
| U.S. offering to investors | 26 |
| U.S. occupied island until 1968 | 31 |
| U.S. observatory | 16 |
| U.S. nuclear sub | 16 |
| U.S. novelist: 1815–82 | 29 |
| U.S. novelist-poet | 18 |
| U.S. novelist | 13 |
| U.S. notable | 12 |