| Supremely favored | 17 |
| Supremely happy | 15 |
| Supremely macho | 15 |
| Supremely mean | 14 |
| Supremely scarce | 16 |
| Supremely softly, in music | 26 |
| Supremely spooky | 16 |
| Supremely stoked | 16 |
| Supremes "Stop! In the Name of ___" | 45 |
| Supremes "Stop! In ___" | 33 |
| Supremes "___ a Symphony" | 35 |
| Supremes "___ Symphony" | 33 |
| Supremes diva | 13 |
| Supremes hit "I ___ Symphony" | 39 |
| Supremes hit, "Back in ___ Again" | 43 |
| Supremes lead singer | 20 |
| Supremes leader | 15 |
| Supremes singer | 15 |
| Supremes singer Diana | 21 |
| Supremes song "I ___ Symphony" | 40 |
| Supremos | 8 |
| Sups | 4 |
| Sups at home | 12 |
| Supt. of school's responsibility | 36 |
| Supt. or prin. | 14 |
| Supt.'s inferior | 20 |
| Supt.'s responsibility | 26 |
| Supung Dam site | 15 |
| Sur citizen | 11 |
| Sur's opposite, in México | 32 |
| Sur's opposite, in Spain | 28 |
| Sura source | 11 |
| Surcease | 8 |
| Surcharge | 9 |
| Surcharge for a cab ride? | 25 |
| Surcharge item in many hotels | 29 |
| Surcoat | 7 |
| Sure | 4 |
| Sure 'nuff | 14 |
| Sure alternative | 16 |
| Sure application spot | 21 |
| Sure bets | 9 |
| Sure competitor | 15 |
| Sure defense | 12 |
| Sure enough, all that money gives him an ___ ... | 48 |
| Sure loser | 10 |
| Sure losers | 11 |
| Sure moneymaker | 15 |
| Sure report card booster | 24 |
| Sure rival | 10 |
| Sure shooter | 12 |
| Sure shot | 9 |
| Sure shots | 10 |
| Sure sign of lion? | 18 |
| Sure sign, for some | 19 |
| Sure signs of density | 21 |
| Sure spots | 10 |
| Sure success | 12 |
| Sure target | 11 |
| Sure target in the locker room? | 31 |
| Sure target? | 12 |
| Sure thing | 10 |
| Sure thing in blackjack | 23 |
| Sure thing! | 11 |
| Sure thing, in British slang | 28 |
| Sure thing, in court | 20 |
| Sure thing, in England | 22 |
| Sure thing, it's said | 25 |
| Sure thing, to a bettor | 23 |
| Sure thing, to a Britisher | 26 |
| Sure thing? | 11 |
| Sure things | 11 |
| Sure things; specific Father's Day gifts? | 45 |
| Sure things? | 12 |
| Sure to attract attention | 25 |
| Sure to be grounded, say | 24 |
| Sure to be won | 14 |
| Sure to bring in money | 22 |
| Sure to end badly | 17 |
| Sure to end in failure, as a situation | 38 |
| Sure to fail | 12 |
| Sure to fascinate | 17 |
| Sure to happen | 14 |
| Sure to receive | 15 |
| Sure to succeed | 15 |
| Sure to vote against | 20 |
| Sure to work | 12 |
| Sure way to fatherhood | 22 |
| Sure way to motherhood | 22 |
| Sure winner | 11 |
| Sure winners | 12 |
| Sure! | 5 |
| Sure, in Dixie | 14 |
| Sure-enough | 11 |
| Sure-footed | 11 |
| Sure-footed animal | 18 |
| Sure-footed animals | 19 |
| Sure-footed beast | 17 |
| Sure-footed beasts | 18 |
| Sure-footed creatures | 21 |