| Big Mac or Whopper | 18 |
| Big Mac ingredients | 19 |
| Big Mac ingredient | 18 |
| Big Mac component | 17 |
| Big Mac alternative, every so often | 35 |
| Big lunk | 8 |
| Big lunch? | 10 |
| Big lunch | 9 |
| Big lump | 8 |
| Big lummoxes | 12 |
| Big lummox | 10 |
| Big lugs | 8 |
| Big lug | 7 |
| Big louts | 9 |
| Big loud display of power | 25 |
| Big lotto win, briefly | 22 |
| Big lotto prize, for short | 26 |
| Big lot | 7 |
| Big loss, so to speak | 21 |
| Big loss, figuratively | 22 |
| Big loss | 8 |
| Big loser's nickname? | 25 |
| Big loser of 1588 | 17 |
| Big long-distance carrier? | 26 |
| Big London landmark | 19 |
| Big London insurer | 18 |
| Big London Guildhall statue | 27 |
| Big London attraction? | 22 |
| Big lobby in D.C. | 17 |
| Big load | 8 |
| Big lizards | 11 |
| Big lizard's tail? | 22 |
| Big lizard | 10 |
| Big list maker | 14 |
| Big lifts | 9 |
| Big lie | 7 |
| Big library books | 17 |
| Big library book | 16 |
| Big letters, for short (and what your answers must be written in to understand the theme) | 89 |
| Big letters on Wall St. | 23 |
| Big letters in trendy handbags | 30 |
| Big letters in racing | 21 |
| Big letters in public broadcasting | 34 |
| Big letters in prog-rock | 24 |
| Big letters in prescriptions | 28 |
| Big letters in fashion | 22 |
| Big letters in cyberspace | 25 |
| Big letters in bowling equipment | 32 |
| Big letters in bowling alleys | 29 |
| Big letters in alleys | 21 |
| Big letter on stationery: Abbr. | 31 |
| Big letter | 10 |
| Big letdown | 11 |
| Big leopards | 12 |
| Big leagues | 11 |
| Big leaguers | 12 |
| Big leaguer's dream? | 24 |
| Big leaguer | 11 |
| Big league: Abbr. | 17 |
| Big league sport | 16 |
| Big lead in a race | 18 |
| Big laughs | 10 |
| Big laugh elicitor | 18 |
| Big laugh | 9 |
| Big land mass | 13 |
| Big lamb cut | 12 |
| Big lake | 8 |
| Big label Sony bought in '08 | 32 |
| Big label in disco music | 24 |
| Big label | 9 |
| Big Korean exports | 18 |
| Big knob, often: Abbr. | 22 |
| Big knives | 10 |
| Big knell | 9 |
| Big klutzes | 11 |
| Big klutz | 9 |
| Big kitchen appliance maker | 27 |
| Big kind of wave | 16 |
| Big kid? | 8 |
| Big KFC order? | 14 |
| Big keyboard key | 16 |
| Big keyboard button | 19 |
| Big key | 7 |
| Big kerfuffles | 14 |
| Big kangaroos | 13 |
| Big kahunas' antitheses | 27 |
| Big kahunas | 11 |
| Big kahuna (with "head") | 34 |
| Big kahuna | 10 |
| Big jump | 8 |
| Big jugs | 8 |
| Big jolt | 8 |
| Big joint | 9 |
| Big John's way out | 22 |
| Big John's tool | 19 |
| Big John of golf | 16 |
| Big Joe Williams "Crawling King ___" | 46 |
| Big Joe holder | 14 |
| Big jobs for a maid | 19 |
| Big job for the makeup department | 33 |