| Big repair bill reaction | 24 |
| Big reindeer | 12 |
| Big refs. | 9 |
| Big reference volume | 20 |
| Big reference book | 18 |
| Big reference | 13 |
| Big ref. works, for short | 25 |
| Big ref. | 8 |
| Big Red? | 8 |
| Big Red, in the N.C.A.A. | 24 |
| Big Red, e.g. | 13 |
| Big Red university | 18 |
| Big Red rivals | 14 |
| Big red poker hand | 18 |
| Big red planet | 14 |
| Big Red opponent | 16 |
| Big Red of horse racing | 23 |
| Big Red Machine shortstop Concepcion | 36 |
| Big Red Machine hustler | 23 |
| Big red dog of kids' TV | 27 |
| Big red dog | 11 |
| Big red clown features | 22 |
| Big Red | 7 |
| Big records | 11 |
| Big recording label | 19 |
| Big recording artists' awards? | 34 |
| Big record label, once | 22 |
| Big record label | 16 |
| Big record inits. | 17 |
| Big record co. | 14 |
| Big recipient of junk mail | 26 |
| Big real estate firm | 20 |
| Big rd. | 7 |
| Big rays | 8 |
| Big ray | 7 |
| Big rattle | 10 |
| Big ratite birds | 16 |
| Big ratite bird | 15 |
| Big range | 9 |
| Big rackets | 11 |
| Big racket | 10 |
| Big race's starting point? | 30 |
| Big race sponsor | 16 |
| Big rabbits | 11 |
| Big rabbit features | 19 |
| Big question of 1980s TV | 24 |
| Big quantity of, informally | 27 |
| Big quantity of juice? | 22 |
| Big quantity | 12 |
| Big quake | 9 |
| Big quackers | 12 |
| Big push to collect singles bar come-ons? | 41 |
| Big purveyor of language lessons | 32 |
| Big purchase of 1867 | 20 |
| Big Pun and Lil Wayne | 21 |
| Big pullers | 11 |
| Big publisher of romance novels | 31 |
| Big publisher in science fiction | 32 |
| Big public to-do | 16 |
| Big public show | 15 |
| Big prowler | 11 |
| Big prov. | 9 |
| Big properties | 14 |
| Big productions | 15 |
| Big production company in 1950s-'60s TV | 43 |
| Big production | 14 |
| Big producer of printers | 24 |
| Big problems of some stars | 26 |
| Big problem? | 12 |
| Big problem on a check | 22 |
| Big problem for a pilot | 23 |
| Big problem at KFC? | 19 |
| Big problem | 11 |
| Big prize since 1901 | 20 |
| Big prize on "The Price Is Right" | 43 |
| Big print: Abbr. | 16 |
| Big print maker | 15 |
| Big primate | 11 |
| Big presence in many small towns | 32 |
| Big prefix in banking | 21 |
| Big prefix | 10 |
| Big potential difference | 24 |
| Big potatoes | 12 |
| Big potato container | 20 |
| Big pot of stew | 15 |
| Big portion of the Mongol Empire | 32 |
| Big popcorn containers | 22 |
| Big popcorn container | 21 |
| Big pooches, familiarly | 23 |
| Big pooch | 9 |
| Big Polynesian fish | 19 |
| Big pollinators | 15 |
| Big political contest | 21 |
| Big pol. campaign donor | 23 |
| Big poker player's wager | 28 |
| Big Poison or Little Poison | 27 |
| Big Poison of baseball | 22 |
| Big poet for java | 17 |
| Big plot | 8 |
| Big player in the Suez Crisis | 29 |