| 2009, in Rome | 13 |
| 2009-'10 "At the Movies" co-host | 46 |
| 2009-'10 Lady Gaga hit | 26 |
| 2009-'11 CIA director Panetta | 33 |
| 2009-10 Super Bowl number | 25 |
| 2009-11 crime drama on Fox | 26 |
| 2009-11 Republican National Committee chairman | 46 |
| 201 | 3 |
| 201 on a slab | 13 |
| 201 or 202, e.g. | 16 |
| 201 to Caesar | 13 |
| 201, as it might be etched in stone | 35 |
| 201, classically | 16 |
| 201, e.g. | 9 |
| 201, in old Rome | 16 |
| 201, to Caesar | 14 |
| 201, to Tiberius | 16 |
| 2010 | 4 |
| 2010 #1 hit by Ke$ha (the 17th song in Billboard history to debut at the top spot) | 82 |
| 2010 "SNL" host Poehler | 33 |
| 2010 "The Karate Kid" costar | 38 |
| 2010 AFC Championship losers | 28 |
| 2010 album from rap's T.I. | 30 |
| 2010 American Idol runner-up | 28 |
| 2010 and 2011 in Cuba | 21 |
| 2010 and 2011 L.P.G.A. Tour Player of the Year Yani ___ | 55 |
| 2010 Angelina Jolie spy film | 28 |
| 2010 Apple arrival | 18 |
| 2010 Apple blockbuster | 22 |
| 2010 Apple debuts | 17 |
| 2010 Apple product | 18 |
| 2010 Apple release | 18 |
| 2010 ballet movie | 17 |
| 2010 Best Picture about a stammering royal | 42 |
| 2010 Best Picture nominee | 25 |
| 2010 best seller by Michael Lewis | 33 |
| 2010 Best Supporting Actress | 28 |
| 2010 BET Hip Hop Awards host Mike | 33 |
| 2010 blizzard nickname | 22 |
| 2010 Broadway musical in which George Wendt played Santa | 56 |
| 2010 chart-topper for Ke$ha | 27 |
| 2010 Coen brothers Western | 26 |
| 2010 coinage meaning "to reject" | 42 |
| 2010 College World Series runner-up | 35 |
| 2010 Denzel Washington title role | 33 |
| 2010 double-platinum Katy Perry album | 37 |
| 2010 earthquake site | 20 |
| 2010 Emma Stone comedy set in high school | 41 |
| 2010 Emma Stone movie | 21 |
| 2010 event featuring vuvuzelas | 30 |
| 2010 FIFA Ballon D'Or winner | 32 |
| 2010 FIFA World Cup finalist | 28 |
| 2010 film "___ Men" | 29 |
| 2010 film "___ Men" or 1984 film "___ Man" | 62 |
| 2010 film about George VI | 25 |
| 2010 film, "Black ___" | 32 |
| 2010 Grammy winner for "Just the Way You Are" | 55 |
| 2010 Grammy-winning rock group | 30 |
| 2010 Grand Slam of Golf champ | 29 |
| 2010 Grauman's Chinese cement honoree | 41 |
| 2010 Guinness world record at 1,689 lbs. | 40 |
| 2010 Guinness world record at 11 ft. 6 in. | 42 |
| 2010 Guinness world record at 115 ft. | 37 |
| 2010 Guinness world record at 72 lbs. 9 oz. | 43 |
| 2010 Gulf problem | 17 |
| 2010 HBO movie where Al Pacino plays Dr. Kevorkian | 50 |
| 2010 health statute, informally | 31 |
| 2010 Heisman Trophy winner Cam Newton's alma mater | 54 |
| 2010 Heisman Trophy winner Newton | 33 |
| 2010 honor for "Up" | 29 |
| 2010 honor for Annie Baker | 26 |
| 2010 hurricane | 14 |
| 2010 installment in the Call of Duty series | 43 |
| 2010 Italian Cannes entry, literally? | 37 |
| 2010 James Mangold action comedy | 32 |
| 2010 Jennifer Aniston movie | 27 |
| 2010 John Goodman movie | 23 |
| 2010 Jude Law thriller | 22 |
| 2010 Jude Law/Forest Whitaker movie | 35 |
| 2010 Kanye West single | 22 |
| 2010 Ke$ha chart-topper with a creatively spelled five-word title | 65 |
| 2010 Leonardo DiCaprio thriller set in a creepy hospital | 56 |
| 2010 Liam Neeson film, with "The" | 43 |
| 2010 Literature Nobelist Mario Vargas __ | 40 |
| 2010 Literature Nobelist Mario Vargas ___ | 41 |
| 2010 Mark Twain Award winner | 28 |
| 2010 Mark Twain Prize winner | 28 |
| 2010 mining disaster locale | 27 |
| 2010 MLB playoff team | 21 |
| 2010 movie Roger Ebert called "an incomprehensible mess with the 1980s TV show embedded inside," with "The" | 127 |
| 2010 movie with a plot to steal the moon | 40 |
| 2010 NBA champs | 15 |
| 2010 NBA Sixth Man of the Year Crawford | 39 |
| 2010 newcomer to Forbes' Celebrity 100 list | 47 |
| 2010 NFL Hall of Fame inductee | 30 |
| 2010 NL MVP Joey | 16 |
| 2010 Nobelist Mario Vargas ___ | 30 |
| 2010 Olympic ice dancing gold medalist ___ Virtue | 49 |
| 2010 Olympic skiing gold medalist Miller | 40 |
| 2010 Open champion | 18 |