| 2008 British Open runner-up Poulter (3) | 39 |
| 2008 Brooke Shields series | 26 |
| 2008 campaign chant | 19 |
| 2008 campaign issue | 19 |
| 2008 campaign personality | 25 |
| 2008 campaign slogan | 20 |
| 2008 campaign theme | 19 |
| 2008 campaign word | 18 |
| 2008 campaigner Mitt | 20 |
| 2008 candidate Barack | 21 |
| 2008 candidate Romney | 21 |
| 2008 candidate with the slogan "Change we can believe in" | 67 |
| 2008 Category 4 | 15 |
| 2008 César Awards presenter | 30 |
| 2008 Clint Eastwood film | 24 |
| 2008 Coen Brothers title, read literally | 40 |
| 2008 computer-animated sci-fi film | 34 |
| 2008 Cusack film about a hunchback | 34 |
| 2008 Cy Young Award winner Cliff | 32 |
| 2008 David Rosenfelt novel featuring businessman Tim Wallace | 60 |
| 2008 Democratic presidential candidate John | 43 |
| 2008 Democratic presidential hopeful whose chances may be extinct? | 66 |
| 2008 demolition target | 22 |
| 2008 Denver conventioneers, informally | 38 |
| 2008 documentary about agribusiness | 35 |
| 2008 documentary about American debt | 36 |
| 2008 documentary about the national debt | 40 |
| 2008 economic stimulus provision | 32 |
| 2008 film "--- 's Island" | 39 |
| 2008 film about a hunchbacked lab assistant | 43 |
| 2008 film derived from Dr. Seuss | 32 |
| 2008 flick "___ Island" | 33 |
| 2008 French Open and Wimbledon champ | 36 |
| 2008 French Open champ Ivanovic | 31 |
| 2008 French Open champion ___ Ivanovic | 38 |
| 2008 French Open winner Ivanovic | 32 |
| 2008 govt. bailout recipient | 28 |
| 2008 greatest hits album that includes the song "Proud Mary" | 70 |
| 2008 Greg Kinnear film | 22 |
| 2008 Harlan Coben thriller | 26 |
| 2008 Harvey Milk portrayer | 26 |
| 2008 historical drama that lost five Academy Awards | 51 |
| 2008 hit for Miley Cyrus | 24 |
| 2008 horror film sequel | 23 |
| 2008 horror movie, or the sound from across the theater that kept breaking my concentration? | 92 |
| 2008 hurricane | 14 |
| 2008 hurricane that hit right before the RNC | 44 |
| 2008 Indy Japan 300 winner __ Patrick | 37 |
| 2008 Infogrames acquisition | 27 |
| 2008 Infogrames merger partner | 30 |
| 2008 is one | 11 |
| 2008 Israeli political biography | 32 |
| 2008 Janet Jackson hit | 22 |
| 2008 Jason Statham thriller | 27 |
| 2008 Jodi Picoult novel ... or a hint to the puzzle theme | 57 |
| 2008 Jordin Sparks duet | 23 |
| 2008 Kathryn Bigelow film about a bomb disposal team | 52 |
| 2008 kids' movie "___'s Island" | 49 |
| 2008 Kingsley-Cruz drama | 24 |
| 2008 L.A.-Phila. showdown | 25 |
| 2008 Liam Neeson movie | 22 |
| 2008 Liam Neeson thriller | 25 |
| 2008 Libertarian Party candidate for President | 46 |
| 2008 Libertarian presidential candidate | 39 |
| 2008 Major League Soccer champion | 33 |
| 2008 Mariah Carey song in dire need of painkillers? | 51 |
| 2008 Mars probe discovery | 25 |
| 2008 Meryl Streep film | 22 |
| 2008 Meryl Streep film title! | 29 |
| 2008 movie remake | 17 |
| 2008 movie with an obsolete title | 33 |
| 2008 N.L. Cy Young Award winner Lincecum | 40 |
| 2008 National League Rookie of the Year Geovany | 47 |
| 2008 NBA Finals losers | 22 |
| 2008 NBA Sixth Man of the Year | 30 |
| 2008 NBC series | 15 |
| 2008 NBC series based on a Defoe novel | 38 |
| 2008 NCAA soccer champs | 23 |
| 2008 NYSE acquisition | 21 |
| 2008 Obie winner Kate | 21 |
| 2008 Olympic gold medalist in men's tennis | 46 |
| 2008 Olympic tennis gold medalist | 33 |
| 2008 Olympics host | 18 |
| 2008 Olympics host, for short | 29 |
| 2008 Olympics host, on the scoreboards | 38 |
| 2008 Olympics protesters | 24 |
| 2008 Olympics sensation | 23 |
| 2008 Olympics site | 18 |
| 2008 Olympics swimmer Dara | 26 |
| 2008 Olympics tennis champion Dementieva | 40 |
| 2008 or 2012 | 12 |
| 2008 Palin counterpart | 22 |
| 2008 party line | 15 |
| 2008 Pixar film about a trash-compacting robot | 46 |
| 2008 Pixar hit | 14 |
| 2008 Pixar movie | 16 |
| 2008 Pixar robot | 16 |
| 2008 presidential candidate | 27 |
| 2008 Presidential debate issue | 30 |
| 2008 presidential debate subject | 32 |