| USC's all-female service organization | 41 |
| Use 140 characters max, in a way | 32 |
| Use a "caret and stick" approach on? | 46 |
| Use a bulletin board only once in a great while? | 48 |
| Use a cell phone outside one's calling area | 47 |
| Use a certain route in a dispute | 32 |
| Use a dildo on a man, as a woman might | 38 |
| Use a divining rod to search for water | 38 |
| Use a fisherman to put the kibosh on? | 37 |
| Use a futuristic mode of transit | 32 |
| Use a grasping device at the barbecue | 37 |
| Use a ladder for love's sake | 32 |
| Use a mouse to move a file between folders, say | 47 |
| Use a portion of, as one song in another | 40 |
| Use a situation to one's advantage | 38 |
| Use a sponge over and over again | 32 |
| Use a time-eating tactic in sports | 34 |
| Use a two-digit confirmation code? | 34 |
| Use a young sheep as a beast of burden? | 39 |
| Use again, in an eco-friendly way | 33 |
| Use Agamemnon's strategy at Troy | 36 |
| Use an obsolete method of adding up numbers? | 44 |
| Use bits of one recording in another | 36 |
| Use brooms to gather the medical staff? | 39 |
| Use cajolement with the coffee bar staff? | 41 |
| Use capital letters in a chat room | 34 |
| Use corporal punishment, in a way | 33 |
| Use it to prevent run-on, perhaps | 33 |
| Use of a company car or private washroom, say | 45 |
| Use of any means to attain an objective | 39 |
| Use of mediation and arbitration, say (abbr.) | 45 |
| Use of ne'er for never, e.g. | 32 |
| Use one's index finger, perhaps | 35 |
| Use one's influence secretly | 32 |
| Use one's thumb for transportation | 38 |
| Use rollers as for one's hair | 34 |
| Use the dining room table, perhaps | 34 |
| Use the phone instead of the stove? | 35 |
| Use, as files, with "to" | 34 |
| Used "th" in place of "s" | 45 |
| Used a beer container as a makeshift canoe? | 43 |
| Used a caret-and-stick approach? | 32 |
| Used a lemon instead of cabbage? | 32 |
| Used a magnifying glass, perhaps | 32 |
| Used a pot for catching, perhaps | 32 |
| Used an alternate route perforce | 32 |
| Used backstage for festival naps | 32 |
| Used by record execs in the '90s | 36 |
| Used by street performer for tips | 33 |
| Used car dealer's allotment? | 32 |
| Used car dealer's spiel, say | 32 |
| Used for star hotel room bookings | 33 |
| Used frugally, with "out" | 35 |
| Used in both masculine and feminine cases | 41 |
| Used marked cards against Godzilla? | 35 |
| Used one's dinner table, say | 32 |
| Used part of someone else's song in yours | 45 |
| Used symbols, as in a musical score | 35 |
| Used the expected number of strokes | 35 |
| Used to sneak into 21-and-over show | 35 |
| Used towels and such at the spa? | 32 |
| Used twice, it forms a sympathy phrase | 38 |
| Used up all the credit on, with 'out' | 45 |
| Used when rocker's jam w/orchestra | 38 |
| Useful advice for a ring referee? | 33 |
| Useful computer command for butterfingers | 41 |
| Useful facts, in casual conversation | 36 |
| Useful gift when looking for an apartment? | 42 |
| Useful item accompanying a face card in blackjack | 49 |
| Useful menu command for fallible folks | 38 |
| Useful thing for dealing with oily fishes | 41 |
| Useful thing for someone taking a dive? | 39 |
| Useful word processing feature for newbies | 42 |
| User of "little gray cells" | 37 |
| User of a pad with a center rule | 32 |
| User of a record-keeping device called a quipu | 46 |
| User of a star-shaped weapon called a shuriken | 46 |
| User of air abrasion to clean teeth | 35 |
| User of both Latin and Cyrillic alphabets | 41 |
| User of the prefix "i-" | 33 |
| User trying to get through a firewall | 37 |
| User who hears "welcome" | 34 |
| User-edited online compendium of notable snippets | 49 |
| Users of slide rules, stereotypically | 37 |
| Users of the dark side of the Force | 35 |
| Uses a blue pencil, traditionally | 33 |
| Uses a certain kitchen appliance | 32 |
| Uses a management training technique | 36 |
| Uses a paper towel on, as a spill | 33 |
| Uses a parachute, with "out" | 38 |
| Uses a parental control, perhaps | 32 |
| Uses a pesticide or fixes software | 34 |
| Uses a strong paper towel, perhaps | 34 |
| Uses an air pressure gauge, perhaps | 35 |
| Uses camouflage, with "in" | 36 |
| Uses discretion instead of valor, maybe | 39 |
| Uses excessively elaborate prose | 32 |
| Uses heated air or pediculicide on | 34 |
| Uses Knorr packets instead of poker chips? | 42 |
| Uses of mentally-based propaganda, in CIA-speak | 47 |