| 2006 Golden Globe Best Actress | 30 |
| 2006 Grammy winner for "Amarantine" | 45 |
| 2006 Grammy-winning blues singer Thomas | 39 |
| 2006 Grammy-winning blues singer ___ Thomas | 43 |
| 2006 hit from The Raconteurs | 28 |
| 2006 hurricane | 14 |
| 2006 Irish musical film | 23 |
| 2006 Jay-Z single | 17 |
| 2006 Ken Jennings book ... or the author himself | 48 |
| 2006 Kennedy Center honoree | 27 |
| 2006 Kentucky Derby winner | 26 |
| 2006 Lifetime Achievement Emmy-winner Bill | 42 |
| 2006 Marion Cotillard romantic comedy | 37 |
| 2006 Mark Twain Prize recipient | 31 |
| 2006 Matt Damon movie | 21 |
| 2006 Michael Connelly crime novel | 33 |
| 2006 Mike Judge dystopian dark comedy | 37 |
| 2006 million-selling Andrea Bocelli album | 41 |
| 2006 movie remake | 17 |
| 2006 movie set in Georgia | 25 |
| 2006 movie starring T.I. | 24 |
| 2006 movie subtitled "Cultural Learnings of America for Make Benefit Glorious Nation of Kazakhstan" | 109 |
| 2006 movie subtitled "The Last Stand" | 47 |
| 2006 N. Korea announcement | 26 |
| 2006 N.B.A. champs | 18 |
| 2006 N.L. MVP | 13 |
| 2006 N.L. MVP __ Howard | 23 |
| 2006 NASCAR Sprint Cup Rookie of the Year Hamlin | 48 |
| 2006 NBA All-Star Game winners | 30 |
| 2006 NBA champions | 18 |
| 2006 NBA championship coach | 27 |
| 2006 NBA champs | 15 |
| 2006 NBA Finals MVP | 19 |
| 2006 NBA Rookie of the Year | 27 |
| 2006 neologism meaning "to demote" | 44 |
| 2006 Newbery Medal winner Lynne ___ Perkins | 43 |
| 2006 Newbery winner Lynne ___ Perkins | 37 |
| 2006 Nintendo collection that included boxing, bowling, and golf | 64 |
| 2006 Nintendo debut | 19 |
| 2006 NLCS venue | 15 |
| 2006 non-fiction work, with "The" | 43 |
| 2006 NSA suer | 13 |
| 2006 Olimpiadi venue | 20 |
| 2006 Olympics figure skating silver medalist | 44 |
| 2006 Olympics host | 18 |
| 2006 Olympics host city in Italy | 32 |
| 2006 Olympics host, to natives | 30 |
| 2006 Olympics site | 18 |
| 2006 Oscar winner for his first film | 36 |
| 2006 Oscar winner Helen | 23 |
| 2006 Pink album | 15 |
| 2006 Pitt/Blanchett movie | 25 |
| 2006 Pixar film | 15 |
| 2006 Pixar hit | 14 |
| 2006 Pixar movie featuring the character Lightning McQueen | 58 |
| 2006 playoff between the Cards and Mets, for short | 50 |
| 2006 political best-seller, with "The" | 48 |
| 2006 portrayer of Fern in 'Charlotte's Web' | 55 |
| 2006 remake of a 1972 film | 26 |
| 2006 Rihanna hit | 16 |
| 2006 role for Forest | 20 |
| 2006 role for Whitaker | 22 |
| 2006 Roman movie based on a comic book? | 39 |
| 2006 romantic drama starring Keanu Reeves and Sandra Bullock | 60 |
| 2006 Samuel L. Jackson movie, initials-wise | 43 |
| 2006 Scarlett Johansson film | 28 |
| 2006 sequel featuring sadistic puzzles | 38 |
| 2006 Soccer Hall of Fame inductee Alexi | 39 |
| 2006 Spike Lee caper film | 25 |
| 2006 Spike Lee crime drama | 26 |
| 2006 spinach invader | 20 |
| 2006 sports retiree | 19 |
| 2006 T.I. film | 14 |
| 2006 tennis retiree | 19 |
| 2006 tennis retiree Navratilova | 31 |
| 2006 Tim McGraw film based on a 1941 Mary O'Hara novel | 58 |
| 2006 title film character who says "Pamela! I no find you attractive anymore! ... Not!" | 97 |
| 2006 Tony-nominated "Sweeney Todd" actress | 52 |
| 2006 TV Land Pioneer Award recipient | 36 |
| 2006 Verizon acquisition | 24 |
| 2006 Verizon purchase | 21 |
| 2006 W.S. champs | 16 |
| 2006 Whirlpool acquisition | 26 |
| 2006 Winter Games setting | 25 |
| 2006 Winter Olympics backdrop | 29 |
| 2006 Winter Olympics city | 25 |
| 2006 Winter Olympics host | 25 |
| 2006 Winter Olympics host city, to locals | 41 |
| 2006 World Baseball Classic runners-up | 38 |
| 2006 World Cup champion | 23 |
| 2006 World Cup champs | 21 |
| 2006 World Cup champs: Abbr. | 28 |
| 2006 World Cup city | 19 |
| 2006 World Cup Final city | 25 |
| 2006 World Cup runner-up | 24 |
| 2006 World Cup winner | 21 |
| 2006 World Series city: Abbr. | 29 |
| 2006 World Series star Scott | 28 |
| 2006 World Series winners' hat letters | 42 |
| 2006 World Series winners, on the scoreboard | 44 |