| 2000s sitcom starring a country singer | 38 |
| 2000s South African president Mbeki | 35 |
| 2000s symbol of corporate financial misconduct | 46 |
| 2000s symbol of corporate misconduct | 36 |
| 2000s teen drama set in California | 34 |
| 2000s teen drama whose opening theme was "California" | 63 |
| 2000s TV drama set in the 1960s | 31 |
| 2000s TV drama that ended in a church | 37 |
| 2000s TV family | 15 |
| 2000s Vienna State Opera conductor | 34 |
| 2000s White House family | 24 |
| 2000s White House nickname | 26 |
| 2000s wireless company | 22 |
| 2000s, e.g.: Abbr. | 18 |
| 2001 | 4 |
| 2001 computer | 16 |
| 2001 computer name | 21 |
| 2001 name | 12 |
| 2001 in old Rome | 17 |
| 2001 to Augustus | 17 |
| 2001 #1 album with the hit "Love Don't Cost a Thing" | 66 |
| 2001 #1 hit for Jennifer Lopez | 30 |
| 2001 "remake" of a 1936 novel | 39 |
| 2001 A.L. M.V.P and Rookie of the Year | 38 |
| 2001 A.L. MVP __ Suzuki | 23 |
| 2001 album featuring "Love Don't Cost a Thing" | 60 |
| 2001 album including the song "Love Don't Cost a Thing" | 69 |
| 2001 album that debuted at #1 | 29 |
| 2001 album with the #1 hit "Ain't It Funny" | 57 |
| 2001 album with the song "Love Don't Cost a Thing" | 64 |
| 2001 and 2010 | 13 |
| 2001 and 2010, for ex. | 22 |
| 2001 Anjelica Huston miniseries, with "The" | 53 |
| 2001 Asia album | 15 |
| 2001 Audrey Tautou film | 23 |
| 2001 bankruptcy company | 23 |
| 2001 bankruptcy filer | 21 |
| 2001 Ben Affleck movie | 22 |
| 2001 Ben Stiller film | 21 |
| 2001 Best Community Site Webby winner | 37 |
| 2001 Best New Artist Grammy winner | 34 |
| 2001 best seller about competitive Scrabble | 43 |
| 2001 biographical film | 22 |
| 2001 biopic | 11 |
| 2001 biopic directed by Michael Mann | 36 |
| 2001 biopic starring Will Smith | 31 |
| 2001 black-and-white film noir starring Billy Bob Thornton | 58 |
| 2001 boxing biopic | 18 |
| 2001 British Open champion | 26 |
| 2001 British Open champion David | 32 |
| 2001 British Open champion David ___ | 36 |
| 2001 British Open winner David | 30 |
| 2001 Cage role | 14 |
| 2001 Canadian peace keeping locale | 34 |
| 2001 Chevron merger partner | 27 |
| 2001 Chris Kattan film | 22 |
| 2001 Christopher Nolan flick | 28 |
| 2001 comedy album | 17 |
| 2001 cult film “Donnie ___” | 35 |
| 2001 David Spade comedy | 23 |
| 2001 David Spade movie | 22 |
| 2001 Dench/Winslet film | 23 |
| 2001 Depeche Mode album | 23 |
| 2001 Disney film subtitled "The Lost Empire" | 54 |
| 2001 drama whose title is taken from "Green Eggs and Ham" | 67 |
| 2001 DreamWorks hit | 19 |
| 2001 Economics Nobelist Michael ___ | 35 |
| 2001 Eminem hit from "The Marshall Mathers LP" | 56 |
| 2001 Emmy nominee for "The West Wing" | 47 |
| 2001 erupter | 12 |
| 2001 filer for Chapter 11 bankruptcy | 36 |
| 2001 film about a boxer | 23 |
| 2001 film bio | 13 |
| 2001 film directed by Jean-Pierre Jeunet | 40 |
| 2001 film directed by Michael Mann | 34 |
| 2001 film featuring Mario Van Peebles as Malcolm X | 50 |
| 2001 film for which Halle Berry won Best Actress | 48 |
| 2001 film for which Jim Broadbent was named Best Supporting Actor | 65 |
| 2001 film set in a mental institution | 37 |
| 2001 film set in Mogadishu | 26 |
| 2001 film starring Guy Pearce | 29 |
| 2001 film that earned Robert Altman a Best Director Oscar nomination | 68 |
| 2001 film whose title refers to an antique gun | 46 |
| 2001 film with five Oscar nominations | 37 |
| 2001 French film comedy or its heroine | 38 |
| 2001 French film featuring Audrey Tautou | 40 |
| 2001 French film nominated for five Academy Awards | 50 |
| 2001 French film nominated for five Oscars | 42 |
| 2001 French film starring Audrey Tautou | 39 |
| 2001 French film with the tag "She'll change your life" | 69 |
| 2001 French romantic comedy | 27 |
| 2001 French title heroine | 25 |
| 2001 Grammy-winning band for the album "Kid A" | 56 |
| 2001 headline maker | 19 |
| 2001 heist film with two sequels | 32 |
| 2001 high-tech debut | 20 |
| 2001 hit for Ja Rule | 20 |
| 2001 hit for Jennifer Lopez | 27 |
| 2001 hit movie musical | 22 |
| 2001 hit on the "J.Lo" CD | 35 |