| First words of the poem | 23 |
| First words on many a stone | 27 |
| First wrong guess in hangman | 28 |
| First year med. school class | 28 |
| First ___ (above all else) | 26 |
| First ___ (all in all) | 22 |
| First ___ (prison newcomers) | 28 |
| First ___ (ship officer) | 24 |
| FIRST ___: 264-41 B.C. | 22 |
| First, second and reverse | 25 |
| First, second and third | 23 |
| First, second or reverse | 24 |
| First, second or third | 22 |
| First, second or third, e.g. | 28 |
| First, Second or Third: Abbr. | 29 |
| First, second, or third | 23 |
| First, second, or third, e.g. | 29 |
| First, second, reverse, etc. | 28 |
| First, second, third and home | 29 |
| First, second, third or home | 28 |
| First, second, third, or home | 29 |
| First, third, or reverse | 24 |
| First-aid applications | 22 |
| First-aid bracer in SE Asia? | 28 |
| First-aid contrivances | 22 |
| First-aid course: Abbr. | 23 |
| First-aid expert, briefly | 25 |
| First-aid experts, briefly | 26 |
| First-aid kits of a sort | 24 |
| First-aid paraphernalia | 23 |
| First-anniversary gift | 22 |
| First-born of siblings | 22 |
| First-century coup victim | 25 |
| First-century Roman despot | 26 |
| First-century Roman emperor | 27 |
| First-century Roman leader | 26 |
| First-class flight amenity | 26 |
| First-class hotel offering | 26 |
| First-class, informally | 23 |
| First-class, so to speak | 24 |
| First-column bingo number | 25 |
| First-cousin's mom | 22 |
| First-day-of-class handout | 26 |
| First-day-of-Latin-class word | 29 |
| First-discovered asteroid | 25 |
| First-down requirement | 22 |
| First-ever NBA lottery pick | 27 |
| First-fl. tenant, often | 23 |
| First-floor apartment number | 28 |
| First-floor apartment, maybe | 28 |
| First-floor apartment, often | 28 |
| First-founded US capital | 24 |
| First-generation hearing aid | 28 |
| First-generation Japanese | 25 |
| First-grade instruction | 23 |
| First-in-line's line | 24 |
| First-known variable star | 25 |
| First-magnitude star in Virgo | 29 |
| First-name in baseball lore | 27 |
| First-of-the-month payment | 26 |
| First-person shooter of 1996 | 28 |
| First-quarter moon tide | 23 |
| First-quarter shipments? | 24 |
| First-quarter-moon tide | 23 |
| First-rate chastisement? | 24 |
| First-rate coffeehouse? | 23 |
| First-rate stand-up comic | 25 |
| First-rate, in British slang | 28 |
| First-rate, informally | 22 |
| First-rate, so to speak | 23 |
| First-rate, to Kipling | 22 |
| First-round KO strategy? | 24 |
| First-sight phenomenon | 22 |
| First-string athletic groups | 28 |
| First-stringers, collectively | 29 |
| First-term Clinton victory | 26 |
| First-time driver, often | 24 |
| First-time drivers, often | 25 |
| First-time pot smoker, maybe | 28 |
| First-time tux wearer, maybe | 28 |
| First-time voter, perhaps | 25 |
| First-year cadet (Var.) | 23 |
| First-year German verb | 22 |
| First-year J.D. candidate | 25 |
| First-year J.D. student | 23 |
| First-year law school class | 27 |
| First-year law student | 22 |
| First-year law students | 23 |
| First-year medical residents | 28 |
| First-year Spanish verb | 23 |
| First-year student, briefly | 27 |
| First-year West Pointer | 23 |
| First-___ (A.R.C. worker) | 25 |
| First; chief: Comb. form | 24 |
| Firstborn's heritage | 24 |
| Firth of Clyde, for one | 23 |
| Firth of Forth facilities? | 26 |
| Fiscal or academic follower | 27 |
| Fischer beat him in Reykjavik | 29 |
| Fischer's best man | 22 |