| First English globe-girdler | 27 |
| First episode in a TV series | 28 |
| First event in a series | 23 |
| First extra baseball inning | 27 |
| First family as of 2009 | 23 |
| First Family at Albany | 22 |
| First family of Chicago | 23 |
| First Family of early Ferrara | 29 |
| First family of Egypt, once | 27 |
| First family of Ferrara | 23 |
| First family of the 1840s | 25 |
| First family of the 1910s | 25 |
| First family of the 1970s | 25 |
| First Family of the 1980s | 25 |
| First family starting in 2009 | 29 |
| First family's address? | 27 |
| First family's grandson | 27 |
| First family's home | 23 |
| First family's home? | 24 |
| First family's residence | 28 |
| First family's residence? | 29 |
| First family's son | 22 |
| First Family, 1909-1913 | 23 |
| First Family: 1881–85 | 28 |
| First fast-food fancier | 23 |
| First female astronaut | 22 |
| First female attorney general | 29 |
| First female in Parliament | 26 |
| First few chips, usually | 24 |
| First FIFA World Cup winner | 27 |
| First fighter to KO Liston | 26 |
| First fill-in on a form | 23 |
| First first name in space | 25 |
| First first name on the moon | 28 |
| First five books of the Bible | 29 |
| First flier lost at sea | 23 |
| First floor apt., perhaps | 25 |
| First form line, usually | 24 |
| First four rows at the Met | 26 |
| First frat at U.C. Berkeley | 27 |
| First fratricide victim | 23 |
| First French head of state? | 27 |
| First full mo. of autumn | 24 |
| First full mo. of fall | 22 |
| First full mo. of spring | 24 |
| First full month of DST | 23 |
| First full month of spring | 26 |
| First game in a series | 22 |
| First game of a double-header | 29 |
| First game of a doubleheader | 28 |
| First game of a series | 22 |
| First game of a twin bill | 25 |
| First game of the season | 24 |
| First game of the series | 24 |
| First game of the year | 22 |
| First game of thseason | 22 |
| First games of the season | 25 |
| First German emperor of Italy | 29 |
| First German president | 22 |
| First given name in the Bible | 29 |
| First goth song, reputedly | 26 |
| First governor of Alaska | 24 |
| First governor of Puerto Rico | 29 |
| First grade presentation | 24 |
| First grader's book | 23 |
| First graders' work | 23 |
| First grandkid of Adam | 22 |
| First grandson in the Bible | 27 |
| First group in a product run | 28 |
| First group of invitees | 23 |
| First group to be invited | 25 |
| First group to get invites | 26 |
| First half of a cassette | 24 |
| First half of a Samoan city | 27 |
| First half of a Senate vote | 27 |
| First half of an album | 22 |
| First half of an inning | 23 |
| First half of an Iowa city | 26 |
| First half of the alphabet | 26 |
| First half of the files? | 24 |
| First Hannibal Lecter novel | 27 |
| First heavyweight champ | 23 |
| First Hebrew calendar month | 27 |
| First Hebrew letter (var.) | 26 |
| First Hebrew letter: Var. | 25 |
| First Hebrew patriarch | 22 |
| First Hebrew patriarch (Var.) | 29 |
| First hit by Rodgers-Hart | 25 |
| First hit by the Police, 1979 | 29 |
| First hit for Otis Redding | 26 |
| First hit for The 4 Seasons | 27 |
| First hit for The Moody Blues | 29 |
| First hit for the Police | 24 |
| First hit for Zhané | 22 |
| First hole in the head? | 23 |
| First Holy Roman emperor | 24 |
| First husband of Bathsheba | 26 |
| First in a classical sequence | 29 |
| First in a historical trio | 26 |
| First in a line of 260+ | 23 |