| Sitcom pal of Barbarino and Horshack | 36 |
| Sitcom pal of Fred | 18 |
| Sitcom palomino | 15 |
| Sitcom pioneer | 14 |
| Sitcom pioneer Arnaz | 20 |
| Sitcom pioneer Desi | 19 |
| Sitcom planet | 13 |
| Sitcom planet first mentioned in an episode of "Happy Days" | 69 |
| Sitcom planet people | 20 |
| Sitcom POW | 10 |
| Sitcom precursor | 16 |
| Sitcom producer | 15 |
| Sitcom producer Norman | 22 |
| Sitcom psychiatrist Frasier, to his patients | 44 |
| Sitcom radio station | 20 |
| Sitcom redhead | 14 |
| Sitcom role for Borgnine | 24 |
| Sitcom role for Brandy | 22 |
| Sitcom role for Brandy Norwood | 30 |
| Sitcom role for Julia | 21 |
| Sitcom role for Nabors | 22 |
| Sitcom samples | 14 |
| Sitcom security device that often defeated its own purpose | 58 |
| Sitcom segment | 14 |
| Sitcom segments | 15 |
| Sitcom sequence | 15 |
| Sitcom sergeant | 15 |
| Sitcom set at a Vermont inn | 27 |
| Sitcom set at Mel's Diner | 29 |
| Sitcom set at the Sunshine Cab Company | 38 |
| Sitcom set during the 1860s | 27 |
| Sitcom set in 1860s Kansas | 26 |
| Sitcom set in a bookstore | 25 |
| Sitcom set in a garage | 22 |
| Sitcom set in a junkyard | 24 |
| Sitcom set in Baltimore | 23 |
| Sitcom set in Brooklyn | 22 |
| Sitcom set in Cowtown, Texas | 28 |
| Sitcom set in Fort Courage | 26 |
| Sitcom set in Hooterville | 25 |
| Sitcom set in Houston | 21 |
| Sitcom set in Korea | 19 |
| Sitcom set in Norwich, Vt. | 26 |
| Sitcom set in Ohio | 18 |
| Sitcom set in Queens | 20 |
| Sitcom set in Texas | 19 |
| Sitcom set in the city | 22 |
| Sitcom set in Tuckahoe, N.Y. | 28 |
| Sitcom set sight | 16 |
| Sitcom sewer worker | 19 |
| Sitcom showing | 14 |
| Sitcom shrink surname | 21 |
| Sitcom sign-off word | 20 |
| Sitcom since 2009 | 17 |
| Sitcom sot | 10 |
| Sitcom souse | 12 |
| Sitcom span | 11 |
| Sitcom spender of brandels and grebbels | 39 |
| Sitcom sports agent Michaels | 28 |
| Sitcom spouse | 13 |
| Sitcom spun off from "The Dukes of Hazzard" | 53 |
| Sitcom star busted for pot in 1998 at his home in West Virginia | 63 |
| Sitcom star Delta | 17 |
| Sitcom star Jillian | 19 |
| Sitcom star Romano | 18 |
| Sitcom star since 1995 | 22 |
| Sitcom star who said "Putting humans in charge of the earth is the cosmic equivalence of letting Eddie Murphy direct" | 127 |
| Sitcom star, often | 18 |
| Sitcom star, perhaps | 20 |
| Sitcom starring a country singer | 32 |
| Sitcom starring a Grammy winner | 31 |
| Sitcom starring a singer | 24 |
| Sitcom starring Bonnie Franklin | 31 |
| Sitcom starring Dick Van Patten | 31 |
| Sitcom starring Sherman Hemsley | 31 |
| Sitcom starring the Mowry twins | 31 |
| Sitcom starring Tim Allen | 25 |
| Sitcom starring Valerie Harper | 30 |
| Sitcom station | 14 |
| Sitcom stock character | 22 |
| Sitcom stopper | 14 |
| Sitcom surname | 14 |
| Sitcom suture? | 14 |
| Sitcom sweeteners | 17 |
| Sitcom teacher at James Buchanan High | 37 |
| Sitcom teacher ___ Kotter | 25 |
| Sitcom test-runs | 16 |
| Sitcom that debuted in 1977 | 27 |
| Sitcom that debuted in 1994 | 27 |
| Sitcom that featured Andy Kaufman | 33 |
| Sitcom that featured the Soup Nazi | 34 |
| Sitcom that gives the backstory on getting to know a bug? | 57 |
| Sitcom that launched Joey Lawrence's career | 47 |
| Sitcom that premiered in '88 | 32 |
| Sitcom that ran from 1974-78 | 28 |
| Sitcom that received 17 Emmy nominations in 2011 | 48 |
| Sitcom that starred a singer | 28 |
| Sitcom that starred Brandy | 26 |
| Sitcom that starred Charles S. Dutton | 37 |
| Sitcom that won 28 Emmys | 24 |