| Isn't completely honest with | 32 |
| Isn't content with the status quo, say | 42 |
| Isn't likely to win any culinary awards | 43 |
| Isn't perfectly perpendicular | 33 |
| Isn't respectful to, in a way | 33 |
| Isn't straight in the middle | 32 |
| Isn't too tight or too loose | 32 |
| Isn't totally out of the race | 33 |
| Isolated (with ''off'') | 39 |
| Isolated flare up disrupted by expedition (11) | 46 |
| Isolated hill surrounded by lava | 32 |
| Isolated, (with "off") | 32 |
| Isolates, as one from among many | 32 |
| Isolationist in the Senate: 1925–45 | 42 |
| ISP featuring CBS Radio stations | 32 |
| ISP that debuted with Windows 95 | 32 |
| ISP that used to mail free trial discs | 38 |
| ISP with a circle-in-a-triangle logo | 36 |
| Israel and India are both part of it | 36 |
| Israel Kamakawiwo'ole's instrument | 42 |
| Israel Military Industries product | 34 |
| Israel Military Industries products | 35 |
| Israel Weapon Industries product | 32 |
| Israel ___ (Irving Berlin, originally) | 38 |
| Israel's "Hatikvah" and others | 44 |
| Israel's "Iron Lady" | 34 |
| Israel's counterpart to the CIA | 35 |
| Israel's defense minister before Menachem | 45 |
| Israel's first ambassador to U.S. | 37 |
| Israel's first female prime minister | 40 |
| Israel's first native-born prime minister | 45 |
| Israel's first U.N. ambassador | 34 |
| Israel's first U.N. delegate | 32 |
| Israel's first U.N. representative | 38 |
| Israel's first UN ambassador | 32 |
| Israel's first United Nations ambassador | 44 |
| Israel's first United Nations ambassador Abba | 49 |
| Israel's former U.N. representative | 39 |
| Israel's Joseph, Levi, et al. | 33 |
| Israel's Minister of Defense: 1967–74 | 48 |
| Israel's Netanyahu, familiarly | 34 |
| Israel's Netanyahu, informally | 34 |
| Israel's oldest daily newspaper | 35 |
| Israel's only female prime minister | 39 |
| Israel's prime minister, 1969-1974 | 38 |
| Israel's prime minister, 1969-74 | 36 |
| Israel's prime minister, in headlines | 41 |
| Israel's ___ Meir: 1898-1978 | 32 |
| Israeli "mentalist" Geller | 36 |
| Israeli actor Ivgy in "Munich" | 40 |
| Israeli ambassador to the U.S. Michael | 38 |
| Israeli ambassador to U.S.: 1982-83 | 35 |
| Israeli character played by Adam Sandler | 40 |
| Israeli city attacked by Napoleon | 33 |
| Israeli city near Ben-Gurion Airport | 36 |
| Israeli city on the Gulf of Aqaba | 33 |
| Israeli diplomat who served in the United Nations | 49 |
| Israeli foreign minister during the Six-Day War | 47 |
| Israeli leader from 1969 to 1974 | 32 |
| Israeli leader Golda born in Kiev | 33 |
| Israeli leader who grew up in Milwaukee | 39 |
| Israeli P.M. during the Yom Kippur War | 38 |
| Israeli place name that means "south" | 47 |
| Israeli political party begun by Begin | 38 |
| Israeli prime minister after Barak | 34 |
| Israeli prime minister after Netanyahu | 38 |
| Israeli prime minister before and after Peres | 45 |
| Israeli prime minister before Rabin | 35 |
| Israeli prime minister before Sharon | 36 |
| Israeli prime minister during the Yom Kippur War | 48 |
| Israeli Prime Minister from Milwaukee | 37 |
| Israeli Prime Minister who resigned in 2001 | 43 |
| Israeli Prime Minister who was ousted in 2001 | 45 |
| Israeli prime minister, 1969-'74 | 36 |
| Israeli seaport on the Gulf of Aqaba | 36 |
| Israeli statesman born in Cape Town, South Africa | 49 |
| Israeli statesman with a palindromic first name | 47 |
| Israeli tourist attraction on the Dead Sea | 42 |
| Israeli weapon named for its designer | 37 |
| Israelite at the conquest of Canaan | 35 |
| Israelite stoned for stealing at Jericho | 40 |
| Issuance of Pontius Pilate, e.g. | 32 |
| Issuances from a robotic monarch? | 33 |
| Issue an embarrassing retraction | 32 |
| Issue associated with inattentiveness | 37 |
| Issue dropped from the Parliament? | 34 |
| Issue for the Occupy Wall Street movement | 41 |
| Issue violently, as matter from a volcano | 41 |
| Issuer of a 1986 report on pornography | 38 |
| Issuer of the Optima credit card, for short | 43 |
| It "has fleas" in an old ditty | 40 |
| It "hits the spot" per an old jingle | 46 |
| It "hits the spot," per old radio ads | 47 |
| It "kills" some people | 32 |
| It "makes the world go round" | 39 |
| It "marches on its stomach" | 37 |
| It "marches on its stomach": Napoleon | 47 |
| It "slayeth the silly one": Job | 41 |
| It "Stands Still" to Rush | 35 |
| It accompanies the speaker of the house? | 40 |