| 1980 Brooke Shields movie | 25 |
| 1980 Carly Simon hit | 20 |
| 1980 Chevy Chase comedy | 23 |
| 1980 Christopher Cross hit | 26 |
| 1980 Chrysler debut | 19 |
| 1980 combatant | 14 |
| 1980 comedy directed by Sidney Poitier | 38 |
| 1980 comedy that "makes 'Meatballs' seem like 'Hamlet,'" according to Leonard Maltin | 110 |
| 1980 David Bowie single | 23 |
| 1980 De Niro film about a boxer | 31 |
| 1980 DeLuise film | 17 |
| 1980 DeLuise flick | 18 |
| 1980 DeLuise title role | 23 |
| 1980 Diana Ross hit | 19 |
| 1980 Disney comedy about an all-night puzzle-solving race | 57 |
| 1980 Dom DeLuise film | 21 |
| 1980 Dom DeLuise movie | 22 |
| 1980 double album by Springsteen | 32 |
| 1980 Eastwood movie | 19 |
| 1980 Economics Nobelist Lawrence | 32 |
| 1980 embargo target | 19 |
| 1980 Erich Segal novel | 22 |
| 1980 erupter | 12 |
| 1980 fadmaker | 13 |
| 1980 film | 9 |
| 1980 film based on a Clive Cussler best seller | 46 |
| 1980 film from David Lynch | 26 |
| 1980 funk album from Slave with the hits "Watching You" and "Snap Shot" | 91 |
| 1980 Gérard Depardieu film | 29 |
| 1980 Gérard Depardieu movie | 30 |
| 1980 Hall of Famer | 18 |
| 1980 Hall of Great Western Performers inductee | 46 |
| 1980 hit by ELO | 15 |
| 1980 hit by The Vapors best enjoyed alone? | 42 |
| 1980 hit for Olivia Newton-John | 31 |
| 1980 hit with the line "I longed to speak but did not dare" | 69 |
| 1980 hit with the lyric "It took a long time to know him" | 67 |
| 1980 horror film set at the Overlook Hotel | 42 |
| 1980 in-flight movie? | 21 |
| 1980 Irene Cara film | 20 |
| 1980 J. Geils Band hit | 22 |
| 1980 John Belushi role | 22 |
| 1980 John Carpenter chiller | 27 |
| 1980 John Carpenter film | 24 |
| 1980 John Carpenter horror film | 31 |
| 1980 John Lennon/Yoko Ono album | 31 |
| 1980 Kenny Rogers hit | 21 |
| 1980 Kool & the Gang hit | 28 |
| 1980 Kurt Russell film | 22 |
| 1980 Laura Ingalls Wilder Award recipient | 41 |
| 1980 Leslie Nielsen film title! | 31 |
| 1980 Maxwell Smart film, with "The" | 45 |
| 1980 Michael Jackson hit | 24 |
| 1980 movie based on a Clive Cussler best seller | 47 |
| 1980 N.F.L. M.V.P. Brian | 24 |
| 1980 N.F.L. Player of the Year | 30 |
| 1980 National Book Award winner, familiarly | 43 |
| 1980 Neil Diamond hit | 21 |
| 1980 new wave classic | 21 |
| 1980 NFL MVP Brian | 18 |
| 1980 NFL MVP Brian __ | 21 |
| 1980 NFL Rookie of the Year | 27 |
| 1980 Nielsen movie | 18 |
| 1980 Olivia Newton-John/ELO hit | 31 |
| 1980 Olympic silver medal hockey letters | 40 |
| 1980 Olympics boycotter | 23 |
| 1980 Olympics host | 18 |
| 1980 Olympics mascot | 20 |
| 1980 Olympics site | 18 |
| 1980 Olympics track star Steve | 30 |
| 1980 or 1984 | 12 |
| 1980 or 2007 | 12 |
| 1980 Oscar winner | 17 |
| 1980 Oscar winner born 12/25/1949 | 34 |
| 1980 Oscar winner Hutton | 24 |
| 1980 Oscar-winner Spacek | 24 |
| 1980 parody film | 16 |
| 1980 Peace Nobelist ___ Pérez Esquivel | 41 |
| 1980 Pointer Sisters hit | 24 |
| 1980 Preakness winner | 21 |
| 1980 Pryor/Wilder comedy | 24 |
| 1980 Pulitzer novelist | 22 |
| 1980 Pulitzer-winning book filled with wordplay and paradoxes | 61 |
| 1980 remake of "Down to Earth" | 40 |
| 1980 Richard Gere film | 22 |
| 1980 Richard Gere portrayal | 27 |
| 1980 Robbie Dupree hit | 22 |
| 1980 Robert De Niro movie | 25 |
| 1980 Robert Hays film | 21 |
| 1980 rock inits. | 16 |
| 1980 role for De Niro | 21 |
| 1980 Rolling Stones hit | 23 |
| 1980 romantic adventure film starring Brooke Shields and Christopher Atkins | 75 |
| 1980 running medalist Steve | 27 |
| 1980 Seymour-Reeve love story | 29 |
| 1980 Shelley Duvall role | 24 |
| 1980 Sidney Poitier autobiography | 33 |
| 1980 Spacek role | 16 |
| 1980 Stacy Keach film The ____ Configuration | 48 |
| 1980 Summer Olympics host | 25 |