| Ed Wood player in "Ed Wood" | 37 |
| Ed who wrote the 87th Precinct novels | 37 |
| Ed who wrote "87th Precinct" novels | 45 |
| Ed who was the longtime voice of Kraft Foods | 44 |
| Ed who voiced Carl in "Up" | 36 |
| Ed who sang "My Cup Runneth Over" | 43 |
| Ed who provided the lead voice in "Up" | 48 |
| Ed who played Santa Claus in "Elf" | 44 |
| Ed who played Mingo on "Daniel Boone" | 47 |
| Ed who had a voice in "Up" | 36 |
| Ed Sullivan offering, as he put it | 34 |
| Ed Sullivan and others, informally | 34 |
| Ed Sheeran song about a smart girl? | 35 |
| Ed Sheeran "The A ___" | 32 |
| Ed of "The People's Court" | 40 |
| Ed of "The Mary Tyler Moore Show" | 43 |
| Ed of "The Honeymooners" | 34 |
| Ed of "Married...With Children" | 41 |
| Ed of "Married With Children" | 39 |
| Ed of "Married ... With Children" | 43 |
| Ed of "A Beautiful Mind" | 34 |
| Ed of ''Lou Grant'' | 35 |
| Ed of ''Hill Street Blues'' | 43 |
| Ed Norton may have been up to his ankles in it | 46 |
| Ed Helms character in "The Hangover" | 46 |
| Ed Harris's "Nixon" role | 38 |
| Ed Harcourt "From Every ___" | 38 |
| Ed Asner's "Up" role | 34 |
| Ecuadorean province named for its gold production | 49 |
| Ecuadorean novelist Juan León ___ | 36 |
| Ecuadorean city has lots of stingers | 36 |
| Ecuadoran volcano that erupted in 1940 | 38 |
| Ecuadoran province once famous for its gold | 43 |
| Ecuadoran province named for its gold production | 48 |
| Ecuadoran province named for a metal | 36 |
| Ecuador's southernmost coastal province | 43 |
| Ecuador's Santa ___ Peninsula | 33 |
| Ecuador's Santa __ Peninsula | 32 |
| Ecuador's neighbor to the south | 35 |
| Ecosystem with world's largest land migration | 49 |
| Economy-boosting government program | 35 |
| Economy car that failed in the U.S. | 35 |
| Economizes, with "down" | 33 |
| Economist's symbol for elasticity | 37 |
| Economist who wrote on population trends | 40 |
| Economist Greenspan, after succeeding Benedict | 46 |
| Economies based on supply and demand | 36 |
| Economics Nobelist William F. ___ | 33 |
| Economics Nobelist Friedman, familiarly | 39 |
| Economical shorthand in store names | 35 |
| Economic sanctions may lead to one | 34 |
| Economic group with political power | 35 |
| Economic figure for a country: Abbr. | 36 |
| Economic bloc headquartered in Indonesia | 40 |
| Ecologically sound energy collectors | 36 |
| Ecological Seuss character, with "The" | 48 |
| Eco-sensitive Dr. Seuss character | 33 |
| Eco-friendly Dr. Seuss character | 32 |
| Eco-friendly deodorant applicator | 33 |
| Eco-friendly computers from Taiwan? | 35 |
| Eco-friendly commuters, for short | 33 |
| Eco's "Il nome della _____" | 41 |
| Eclipse, to some ancient cultures | 33 |
| Eclipse, maybe, to primitive peoples | 36 |
| Eclipse ... black cat ... future | 32 |
| Eclectic painter: 1575–1642 | 34 |
| Eclectic magazine founded in 1984 | 33 |
| Eckhart of "The Dark Knight" | 38 |
| Eckhart of "Thank You for Smoking" | 44 |
| Echolocating devices on submarines | 34 |
| Echo & the Bunnymen frontman McCulloch | 42 |
| Echinoderm with regenerable arms | 32 |
| Ecclesiastical group dined on chicken | 37 |
| Ecclesiastic next below a bishop | 32 |
| Eccentric Tom Hanks comedy, with "The" | 48 |
| Eccentric senior, affectionately | 32 |
| Eccentric friend on "Designing Women" | 47 |
| Ebro and Guadalquivir, por ejemplo | 34 |
| Ebert's partner after Siskel | 32 |
| Ebenezer's ghostly first visitor | 36 |
| Ebenezer's ghostly ex-partner | 33 |
| Ebenezer's "___! Humbug!" | 39 |
| Eb equivalent, in some temperaments | 35 |
| Eavesdropper in Act III of "Aïda" | 46 |
| Eaves hanger that attracts insects | 34 |
| Eats, with "up" or "down" | 45 |
| Eats voraciously, with "down" | 39 |
| Eats voraciously (with "down") | 40 |
| Eats too much of, with "on" | 37 |
| Eats more of than is wise, with "on" | 46 |
| Eats greedily (with "down") | 37 |
| Eats eagerly, with "down" | 35 |
| Eating-contest winner, figuratively | 35 |
| Eating-contest fodder, sometimes | 32 |
| Eating regimen that really ticks you off? | 41 |
| Eating record #4 (141 pieces in six minutes) | 44 |
| Eating record #2 (set on Thanksgiving, 2003) | 44 |
| Eating heartily at Thanksgiving? | 32 |
| Eating contest winner's paunch? | 35 |
| Eatery with a "Two x Two x Two" option | 48 |