| Sega Genesis competitor, initially | 34 |
| Sega hedgehog | 13 |
| Sega mascot | 11 |
| Sega racing classic with a Ferrari | 34 |
| Sega rival | 10 |
| Sega robot | 10 |
| Sega's hedgehog | 19 |
| Segal | 5 |
| Segal and Fromm | 15 |
| Segal best seller | 17 |
| Segal or Fromm | 14 |
| Segal phenomenon | 16 |
| Segal product | 13 |
| Segal seethes? | 14 |
| Segal who wrote "Love Story" | 38 |
| Segal's "Oliver's ___" | 40 |
| Segal's "The ___" | 31 |
| Segal's "___ Story" | 33 |
| Segar created her | 17 |
| Segar or seegar | 15 |
| Segar who created Popeye | 24 |
| Segar's Alice | 17 |
| Segar's Olive | 17 |
| Seger "Fire Down ___" | 31 |
| Seger "The Fire Down ___" | 35 |
| Seger's "Still The ___" | 37 |
| Seger: "___ it Shines" | 32 |
| Segment | 7 |
| Segment at La Scala | 19 |
| Segment covered by a test, perhaps | 34 |
| Segment from "The Nutcracker" | 39 |
| Segment of a corolla | 20 |
| Segment of a flight | 19 |
| Segment of a gig | 16 |
| Segment of a journey | 20 |
| Segment of a trip | 17 |
| Segment of an angling contest? | 30 |
| Segment of cricket | 18 |
| Segment of Dante's "Inferno"? | 43 |
| Segment of history | 18 |
| Segment of land | 15 |
| Segment of Oregon Trail | 23 |
| Segment of the western Pacific | 30 |
| Segment or shard | 16 |
| Segmented army | 14 |
| Segmented bar brand | 19 |
| Segmented crustacean | 20 |
| Segmented worm | 14 |
| Segmented worms | 15 |
| Segments | 8 |
| Segments along a circumference | 30 |
| Segments of "Silent Movie"? | 37 |
| Segments of a curve | 19 |
| Segments of a whole | 19 |
| Segments of an act | 18 |
| Segments of books | 17 |
| Segments of DNA | 15 |
| Segments of eternity | 20 |
| Segments of history | 19 |
| Segments of insects' legs | 29 |
| Segments of postgame shows | 26 |
| Segments of some marathons | 26 |
| Segments of sonnets | 19 |
| Segments of worms | 17 |
| Segments: Abbr. | 15 |
| Sego state | 10 |
| Sego-flower state | 17 |
| Sego-lily state | 15 |
| Segovia and friends | 19 |
| Segovia's companion | 23 |
| Segovia's instrument | 24 |
| Segovia, e.g. | 13 |
| Segregate faulty computer code that only some know about (6, 3) | 63 |
| Segregated | 10 |
| Segregated area | 15 |
| Segregated section | 18 |
| Segue | 5 |
| Segue after getting sidetracked | 31 |
| Segue starter | 13 |
| Segue to a conclusion | 21 |
| Segue to a surprise story ending | 32 |
| Segue word | 10 |
| Segueing phrase | 15 |
| Segues in a '50s-'60s sitcom? | 37 |
| Segundo matrimonio result, maybe? | 33 |
| Segway alternative | 18 |
| Segway inventor Dean ___ | 24 |
| Segway inventor Kamen | 21 |
| Sei + uno | 9 |
| Sei halved | 10 |
| Sei school | 10 |
| Sei's cousin | 16 |
| Seibur? | 7 |
| Seidel filler | 13 |
| Seidel filler, sometimes | 24 |
| Seidel's relative | 21 |
| Seigneur de Montaigne's output | 34 |
| Seiji of the symphony | 21 |
| Seiji Ozawa led it for nearly 30 yrs. | 37 |
| Seiji ___, longtime Boston Symphony maestro | 43 |