| Second Amendment supporters: Abbr. | 34 |
| Second Amendment topic | 22 |
| Second Amendment verb | 21 |
| Second Amendment word | 21 |
| Second Amendment-supporting gp. | 31 |
| Second Amendment-touting gp. | 28 |
| Second American in space | 24 |
| Second American to fly in space | 31 |
| Second and third in a sequence | 30 |
| Second appearance on a soundtrack | 33 |
| Second attempt | 14 |
| Second attempt at a phone call? | 31 |
| Second attempt to film | 22 |
| Second attempts | 15 |
| Second audition | 15 |
| Second avenue on a Monopoly board | 33 |
| Second ballot, often | 20 |
| Second banana | 13 |
| Second banana in the kitchen | 28 |
| Second banana of a sort | 23 |
| Second bananas | 14 |
| SECOND BASEMAN | 14 |
| Second baseman Bobby whose #1 was retired by the Red Sox | 56 |
| Second baseman Boone | 20 |
| Second baseman called "The Crab" | 42 |
| Second baseman for the Big Red Machine | 38 |
| Second baseman in a famed trio | 30 |
| Second baseman in both of the Dodgers' 1980s World Series | 61 |
| Second baseman Matsui | 21 |
| Second baseman Matsui, to fans | 30 |
| Second baseman of comedy | 24 |
| Second baseman Roberto | 22 |
| Second baseman Sandberg | 23 |
| Second baseman Santiago | 23 |
| Second Beatles film | 19 |
| Second Beatles movie | 20 |
| Second beginning? | 17 |
| Second best | 11 |
| Second biggest city in Russia's Orenburg region | 51 |
| Second bk. of the Torah | 23 |
| Second book of Moses: Abbr. | 27 |
| Second book of Pearl S. Buck's "Good Earth" trilogy | 65 |
| Second book of the Torah | 24 |
| Second breakfast | 16 |
| Second Bull Run victor | 22 |
| Second caliph | 13 |
| Second careers for thoroughbreds | 32 |
| Second caution | 14 |
| Second century date | 19 |
| Second cervical vertebra | 24 |
| Second chance | 13 |
| Second chance for couch potatoes | 32 |
| Second chance for viewers | 25 |
| Second chance in court | 22 |
| Second chance in education? | 27 |
| Second chance in school | 23 |
| Second chance, of a sort | 24 |
| Second chances | 14 |
| Second chances for students | 27 |
| Second chances in school | 24 |
| Second checkup | 14 |
| Second child | 12 |
| Second childhood | 16 |
| Second choice | 13 |
| Second city of Japan | 20 |
| Second city of the U.S. | 23 |
| Second City specialty | 21 |
| Second City transportation agcy. | 32 |
| Second City's #1 airport | 28 |
| Second city, for short | 22 |
| Second class, perhaps | 21 |
| Second cleaning | 15 |
| Second cliché of the speech | 30 |
| Second club member | 18 |
| Second column | 13 |
| Second column from the right | 28 |
| Second come-on | 14 |
| Second coming | 13 |
| Second coming? | 14 |
| Second commandment no-no | 24 |
| Second Commandment preposition | 30 |
| Second Commandment prohibition | 30 |
| Second Commandment subject | 26 |
| Second Commandment taboo | 24 |
| Second Commandment violator | 27 |
| Second Commandment violators | 28 |
| Second Commandment word | 23 |
| Second consonant | 16 |
| Second Council of Constantinople year | 37 |
| Second course? | 14 |
| Second courses | 14 |
| Second court hearing | 20 |
| Second cousin? | 14 |
| Second cranial nerve | 20 |
| Second crop of a growing season | 31 |
| Second cup of coffee | 20 |
| Second cup of coffee, e.g. | 26 |
| Second daughter of James II | 27 |
| Second day gift | 15 |
| Second deal | 11 |