| San Diego wives, perhaps | 24 |
| San Diego Zoo attraction | 24 |
| San Diego Zoo attraction? | 25 |
| San Diego Zoo attractions | 25 |
| San Diego Zoo inhabitant | 24 |
| San Diego __ | 12 |
| San Diego's area, for short | 31 |
| San Diego's Bai Yun and Gao Gao, e.g. | 41 |
| San Diego's founder Gaspar de ___ | 37 |
| San Diego's neighbor | 24 |
| San Diego's region, for short | 33 |
| San Diego's ___ Pines, site of the 2008 U.S. Open | 53 |
| San Diego-area horse-racing venue | 33 |
| San Diego-to-Albuquerque dir. | 29 |
| San Diego-to-Seattle rte. | 25 |
| San Diego-to-Tijuana dir. | 25 |
| San Diego-to-Vegas dir. | 23 |
| San Fernando creator of fake van Goghs? | 39 |
| San Fernando Valley city | 24 |
| San Fernando Valley community | 29 |
| San Fernando Valley district | 28 |
| San Fernando Valley locale | 26 |
| San Fernando Valley neighborhood | 32 |
| San Fernando ___ (Skelton character) | 36 |
| San Fernando, e.g. | 18 |
| San Fernando, for one | 21 |
| San Filippo ___ (Italian mystic) | 32 |
| San follower | 12 |
| San Fran band Erase ___ | 23 |
| San Fran footballer | 19 |
| San Fran gridder | 16 |
| San Fran NFLer | 14 |
| San Fran pro | 12 |
| San Fran rockers on bikes? (Abbr.) | 34 |
| San Fran setting | 16 |
| San Fran transit system | 23 |
| San Fran. to Houston | 20 |
| San Fran? | 9 |
| San Francisco | 13 |
| San Francisco 49ers CEO York | 28 |
| San Francisco and environs | 26 |
| San Francisco and Guantanamo, e.g. (4) | 38 |
| San Francisco and Thunder | 25 |
| San Francisco area | 18 |
| San Francisco area athlete? | 27 |
| San Francisco arena | 19 |
| San Francisco attraction | 24 |
| San Francisco ballplayer, briefly | 33 |
| San Francisco Bay attraction | 28 |
| San Francisco Bay city | 22 |
| San Francisco Bay landmark | 26 |
| San Francisco Bay opening | 25 |
| San Francisco Bay structure | 27 |
| San Francisco Bay tourist attraction | 36 |
| San Francisco Bay's __ Buena island | 39 |
| San Francisco Bay's ___ Buena Island | 40 |
| San Francisco bread | 19 |
| San Francisco bridge | 20 |
| San Francisco carrier | 21 |
| San Francisco Chronicle parent company | 38 |
| San Francisco conveyance | 24 |
| San Francisco cop of film | 25 |
| San Francisco detective on wheels on '60s TV | 48 |
| San Francisco disaster of 1989, the Loma ___ quake | 50 |
| San Francisco district | 22 |
| San Francisco district, with "the" | 44 |
| San Francisco district, with “The” | 42 |
| San Francisco feature | 21 |
| San Francisco footballer, briefly | 33 |
| San Francisco footballer, in brief | 34 |
| San Francisco footballers, for short | 36 |
| San Francisco founder | 21 |
| San Francisco founder JunÃpero | 33 |
| San Francisco garrison | 22 |
| San Francisco gay rights martyr played by Sean Penn in a 2008 film | 66 |
| San Francisco Giants closer Sergio | 34 |
| San Francisco gridder | 21 |
| San Francisco gridder, briefly | 30 |
| San Francisco gridder, familiarly | 33 |
| San Francisco hangout of the sixties | 36 |
| San Francisco high spot | 23 |
| San Francisco hill | 18 |
| San Francisco hill name | 23 |
| San Francisco landmark | 22 |
| San Francisco locale | 20 |
| San Francisco mayor | 19 |
| San Francisco mayor Joseph | 26 |
| San Francisco mayor Newsom | 26 |
| San Francisco mayor, 1968-'76 | 33 |
| San Francisco mayor, 1968-1976 | 30 |
| San Francisco neighborhood | 26 |
| San Francisco neighborhood, with "the" | 48 |
| San Francisco newspaper | 23 |
| San Francisco NFLer | 19 |
| San Francisco NFLers, for short | 31 |
| San Francisco nine | 18 |
| San Francisco pants-maker | 25 |
| San Francisco paper, briefly (with "the") | 51 |
| San Francisco player | 20 |
| San Francisco player, briefly | 29 |