| Safety or rolling | 17 |
| Safety or tie | 13 |
| Safety org. | 11 |
| Safety org. founded in 1980 | 27 |
| Safety outlet | 13 |
| Safety pair: Abbr. | 18 |
| Safety program | 14 |
| Safety prop | 11 |
| Safety rail on a railroad | 25 |
| Safety regulatory org. | 22 |
| Safety restraint | 16 |
| Safety rods in shower stalls | 28 |
| Safety sash for a spaceman? | 27 |
| Safety setting | 14 |
| Safety shoe feature | 19 |
| Safety signal | 13 |
| Safety specifications | 21 |
| Safety spot | 11 |
| Safety squeeze result, for short | 32 |
| Safety standards | 16 |
| Safety stats. | 13 |
| Safety strap | 12 |
| Safety zone | 11 |
| Safety ___ | 10 |
| Safety, e.g. | 12 |
| Safety, for one | 15 |
| Safety-brake inventor | 21 |
| Safety-razor inventor | 21 |
| Safeway rival | 13 |
| Safflower by-product | 20 |
| Safflower derivative | 20 |
| Safflower product | 17 |
| Safflower ___ | 13 |
| Saffron | 7 |
| Saffron amt., perhaps | 21 |
| Saffron and ginger | 18 |
| Saffron flowers | 15 |
| Saffron or sage, e.g. | 21 |
| Saffron sources | 15 |
| Saffron's mom on "Ab Fab" | 39 |
| Saffron's mom on "Absolutely Fabulous" | 52 |
| Saffron-and-rice dish | 21 |
| Saffron-and-rice recipe | 23 |
| Saffron-flavored dish | 21 |
| Saffron-flavored dish dedicated to the Queen of Jazz? | 53 |
| Saffron-flavored dish with rice | 31 |
| Saffron-flavored rice dish | 26 |
| Saffron-flavored Spanish dish | 29 |
| Saffron-flavored stew | 21 |
| Saffron-rice dish | 17 |
| Saffron-seasoned shellfish dish | 31 |
| Saffron-seasoned Spanish staple | 31 |
| Saffron-yielding blooms | 23 |
| Safin who won the 2005 Australian Open | 38 |
| Safire subject | 14 |
| Sag | 3 |
| Sag down | 8 |
| SAG ex-president | 16 |
| Sag in the sun | 14 |
| SAG Life Achievement honoree of '01 | 39 |
| SAG member | 10 |
| SAG member's rep | 20 |
| Sag on a nag | 12 |
| Sag ___ (curried spinach and potatoes) | 38 |
| SAG's partner | 17 |
| Sag, as flowers | 15 |
| SAG-___ (actors' union) | 27 |
| Saga | 4 |
| Saga in verse | 13 |
| Saga name | 9 |
| Saga of the heart | 17 |
| Saga set in a "galaxy far, far away" | 46 |
| Saga start | 10 |
| Saga that ended with "Breaking Dawn" | 46 |
| Saga with Chicken George | 24 |
| Saga's relative | 19 |
| Saga, Norse style | 17 |
| Sagacious | 9 |
| Sagacious lawgiver | 18 |
| Sagacious sorts | 15 |
| Sagacity | 8 |
| Sagal of "8 Simple Rules..." | 38 |
| Sagal of "Married ... With Children" | 46 |
| Sagal of "Married with Children" | 42 |
| Sagal of "Married...With Children" | 44 |
| Sagaman | 7 |
| Sagan and Sandburg | 18 |
| Sagan novel | 11 |
| Sagan of "Cosmos" | 27 |
| Sagan or Jung | 13 |
| Sagan or Perkins | 16 |
| Sagan or Reiner | 15 |
| Sagan or Sandburg | 17 |
| Sagan series | 12 |
| Sagan subject | 13 |
| Sagan topic | 11 |
| Sagan's ''The Dragons of _____'' | 52 |
| Sagan's "pale blue dot" | 37 |
| Sagan's "The Dragons of ___" | 42 |
| Sagan's "_____ Brain" | 35 |