| ___ Sea (shrinking body of water) | 33 |
| ___ Sea (shrinking body of water in Asia) | 41 |
| ___ Sea (part of the South Atlantic) | 36 |
| ___ Sea (part of Jordan's boundary) | 39 |
| ___ Sea (Kazakhstan body of water) | 34 |
| ___ Sea (inland body with high salinity) | 40 |
| ___ Sea (greatly shrunken body of water) | 40 |
| ___ Sea (arm of the Arctic Ocean) | 33 |
| ___ Sea (Amu Darya's outlet) | 32 |
| ___ Se (NYC Michelin three-star restaurant) | 43 |
| ___ Sculptoris, southern constellation | 38 |
| ___ Scowcroft, former presidential adviser | 42 |
| ___ Science Fiction & Fact (magazine) | 41 |
| ___ sci (college major, informally) | 35 |
| ___ Schwarz (noted N.Y. toy store) | 34 |
| ___ school (precollege institution) | 35 |
| ___ school (pre-college institution) | 36 |
| ___ School (early 20th-century art group) | 41 |
| ___ school (doctor's training) | 34 |
| ___ School (20th-century art group) | 35 |
| ___ scheme (eponymous investment scam) | 38 |
| ___ scan (biometric authentication method) | 42 |
| ___ Scamander, pseudonym of J. K. Rowling | 41 |
| ___ scale (mineral hardness measure) | 36 |
| ___ saw (carpenter's curve cutter) | 38 |
| ___ Savy Fav (New York City indie band) | 39 |
| ___ Saud, founder of Saudi Arabia | 33 |
| ___ Saud (Saudi Arabia's founder) | 37 |
| ___ Saud (former Mideast leader) | 32 |
| ___ sauce (raspberry dessert topping) | 37 |
| ___ Sark, a Channel Islands ruler | 33 |
| ___ Santiago, 1987 N.L. Rookie of the Year | 42 |
| ___ Salty's (potato chip brand) | 35 |
| ___ Salonga, "Miss Saigon" actress | 44 |
| ___ salad (dish with ground beef) | 33 |
| ___ salad (dish featuring bacon and egg) | 40 |
| ___ Saint-Louis (solid ground in the Seine) | 43 |
| ___ Sailer, three-time 1956 skiing gold medalist | 48 |
| ___ Sad (Serbia's second-largest city) | 42 |
| ___ sac (pouch between bones and tendons) | 41 |
| ___ Sabha, India's lower house | 34 |
| ___ sabaki (martial arts movement) | 34 |
| ___ Saab (French fashion designer) | 34 |
| ___ Ryerson in "Groundhog Day" | 40 |
| ___ Ryan, a k a the Ryan Express | 32 |
| ___ Rutherford, the Father of Nuclear Physics | 45 |
| ___ Ruler, Secretariat's sire | 33 |
| ___ Ruins National Monument, N.M. | 33 |
| ___ Rud, river on Afghanistan's boundary | 44 |
| ___ Royale (Lake Superior feature) | 34 |
| ___ Royal, W.W. II aircraft carrier | 35 |
| ___ Row (bespoke tailoring locale) | 34 |
| ___ roster (eligible team members) | 34 |
| ___ Ross, author of "Wisconsin" | 41 |
| ___ Ross Bridge (Delaware crosser) | 34 |
| ___ Roses (band that returned with a 2008 album) | 48 |
| ___ Rosebud, 1914 Kentucky Derby winner | 39 |
| ___ Rosada (Argentine presidential manor) | 41 |
| ___ Rosada (Argentine presidentÂ’s office) | 45 |
| ___ Root, Nobelist for Peace: 1912 | 34 |
| ___ room (site for a Ping-Pong table) | 37 |
| ___ Room (largest room in the White House) | 42 |
| ___ Romero, onetime player of the Joker | 39 |
| ___ Rom ("Lost" Other) | 32 |
| ___ roll (experiences good luck) | 32 |
| ___ Roker (Hannah Montana's bodyguard) | 42 |
| ___ Roger de Coverley (country dance) | 37 |
| ___ rod (molding with a twined serpent design) | 46 |
| ___ Rock, Australian tourist attraction | 39 |
| ___ Rock Pete (Diesel Sweeties character) | 41 |
| ___ Rock (war-themed DC Comics character) | 41 |
| ___ rock (some George Harrison music) | 37 |
| ___ Rock (landmark also called Uluru) | 37 |
| ___ rock (category for Yes and Genesis) | 39 |
| ___ Rock (Australian tourist site) | 34 |
| ___ Road (W.W. II Asian highway) | 32 |
| ___ Rizzo, "Midnight Cowboy" role | 43 |
| ___ Rizzo of "Midnight Cowboy" | 40 |
| ___ Rivoli (arcaded Paris street) | 33 |
| ___ River (what the Brooklyn Bridge spans) | 42 |
| ___ River (what the Brooklyn Bridge crosses over) | 49 |
| ___ River (seat of New Jersey's Ocean County) | 49 |
| ___ riot act (reprimand severely) | 33 |
| ___ rigueur (to the fullest extent) | 35 |
| ___ Ridge: 1972 Kentucky Derby winner | 37 |
| ___ Ridge, Kentucky Derby winner, 1972 | 38 |
| ___ Ridge (1972 Kentucky Derby winner) | 38 |
| ___ Ridge ('72 Belmont winner) | 34 |
| ___ Rida ("Right Round" rapper) | 41 |
| ___ Rida ("Low" performer with T-Pain) | 48 |
| ___ Rico (Spanish name for Scrooge McDuck) | 42 |
| ___ Revolution (2005 Lebanese uprising) | 39 |
| ___ Research Center (think tank) | 32 |
| ___ Research Center (NASA lab in Silicon Valley) | 48 |
| ___ Report (luxury lifestyle magazine) | 38 |
| ___ Report (high-end lifestyle mag) | 35 |
| ___ release (message targeted to the media) | 43 |
| ___ Relays (annual sporting event) | 34 |
| ___ Relaxo (one-time getaway for Marge Simpson) | 47 |
| ___ regni (in the year of the reign) | 36 |