| Epic with heroic rebels | 23 |
| Epicure's condiment | 23 |
| Epicurean appreciation | 22 |
| Epidemic-fighting org. | 22 |
| Epidemiologist's concern | 28 |
| Epidemiologist's study | 26 |
| Epidemiology org. in Atlanta | 28 |
| Epilogue or coda, e.g. | 22 |
| Epinephrine-producing gland | 27 |
| Epinephrine-producing glands | 28 |
| Epinephrine-releasing gland | 27 |
| Episcopal chapel leader | 23 |
| Episcopal jurisdictions | 23 |
| Episode of overindulgence | 25 |
| Epistle appendage: Abbr. | 24 |
| Epistle of the New Testament | 28 |
| Epistolary courtesy: Abbr. | 26 |
| Epitaph opener, perhaps | 23 |
| Epithet across the pond | 23 |
| Epithet for a Cardinal | 22 |
| Epithet for a computer whiz | 27 |
| Epithet for a famed Briton | 26 |
| Epithet for a glasses wearer | 28 |
| Epithet for a Russian soldier | 29 |
| Epithet for a Sikh deity | 24 |
| Epithet for Alexander Pope | 26 |
| Epithet for Anthony Wayne | 25 |
| Epithet for Clemenceau | 22 |
| Epithet for Clio, Erato, etc. | 29 |
| Epithet for Elizabeth I | 23 |
| Epithet for Ethelred II | 23 |
| Epithet for Gildersleeve | 24 |
| Epithet for Harry Callahan | 26 |
| Epithet for Junior, maybe | 25 |
| Epithet for many a lemon | 24 |
| Epithet for many a rapper | 25 |
| Epithet for Nadya Suleman | 25 |
| Epithet for Pope John Paul II | 29 |
| Epithet for Sam or Remus | 24 |
| Epithet for Samuel Johnson | 26 |
| Epithet for Shakespeare | 23 |
| Epithet for some dissenters | 27 |
| Epithet for St. George | 22 |
| Epithet for the Yankees | 23 |
| Epithet for Worms, Ger. | 23 |
| Epithet from the villain | 24 |
| Epithet given Lou Gehrig | 24 |
| Epithet hurled at Occupiers | 27 |
| Epithet meaning tentmaker | 25 |
| Epithet of the Virgin Mary | 26 |
| Epithet used by H.S.T. | 22 |
| Epithet used in politics | 24 |
| Epitome of class in dance | 25 |
| Epitome of elusiveness | 22 |
| Epitome of handsomeness | 23 |
| Epitome of slenderness | 22 |
| Epitome of slipperiness | 23 |
| Epitome of stubbornness | 23 |
| Epitomes of self-sacrifice | 26 |
| Epitomes of stubbornness | 24 |
| Epoch 50 million years ago | 26 |
| Epoch after the Eocene | 22 |
| Epoch in the Tertiary Period | 28 |
| Epoch in which mammals arose | 28 |
| Epoch of 50 million years ago | 29 |
| Epoch of the Tertiary Period | 28 |
| Epoch when mammals appeared | 27 |
| Epoch when mammals arose | 24 |
| Epoch when mammals began | 24 |
| Epoch with lots of fish | 23 |
| Epoch's English cousin | 26 |
| Eponym for a day of the week | 28 |
| Eponym for a great city | 23 |
| Eponym for a measure of speed | 29 |
| Eponym for an IRA variety | 25 |
| Eponym for the fifth of seven | 29 |
| Eponym indicating failure | 25 |
| Eponym of a frozen fish line | 28 |
| Eponym of a frozen food | 23 |
| Eponym of a gymnastics flip | 27 |
| Eponym of a luncheon snack | 26 |
| Eponym of a New York island | 27 |
| Eponym of a Venetian basilica | 29 |
| Eponym of an African capital | 28 |
| Eponym of an Eastern state | 26 |
| Eponym of the 45th state | 24 |
| Eponym's contribution | 25 |
| Eponymic New Jersey city | 24 |
| Eponymous '90s talk show | 28 |
| Eponymous 1969 jazz album | 25 |
| Eponymous 2001 pop album | 24 |
| Eponymous associate of Stalin | 29 |
| Eponymous Austrian skater | 25 |
| Eponymous bacteriologist | 24 |
| Eponymous beekeeper Shavitz | 27 |
| Eponymous Belgian town | 22 |
| Eponymous botanist Anders | 25 |
| Eponymous British baker Sally | 29 |
| Eponymous British Bobby | 23 |
| Eponymous burner designer | 25 |