| ___ middling | 12 |
| ___ Middlecoff, 1949 and 1956 U.S. Open champ | 45 |
| ___ Michigan | 12 |
| ___ Michele of "Glee" | 31 |
| ___ Michaels of "S.N.L." | 34 |
| ___ Mich', in Paree | 23 |
| ___ mi (Vietnamese sandwich) | 28 |
| ___ mgr. | 8 |
| ___ Meyers, first woman to sign with an NBA team (the Pacers) | 61 |
| ___ Metro (bygone car) | 22 |
| ___ Methuselah | 14 |
| ___ method | 10 |
| ___ Meteor Shower | 17 |
| ___ metal (tin-lead alloy) | 26 |
| ___ metal (plating alloy) | 25 |
| ___ metal (nickel alloy) | 24 |
| ___ metal | 9 |
| ___ metabolism rate | 19 |
| ___ metabolism | 14 |
| ___ Messenger (instant messaging software) | 42 |
| ___ messaging (modern communication) | 36 |
| ___ message (signal one's intentions) | 41 |
| ___ message (made one's point) | 34 |
| ___ message | 11 |
| ___ mess (strawberries and cream dish) | 38 |
| ___ mess | 8 |
| ___ meson (particle that is its own antiparticle) | 49 |
| ___ Mesa, L.A. suburb | 21 |
| ___ Mesa, California | 20 |
| ___ Mesa, Calif. city | 21 |
| ___ Mesa, Calif. | 16 |
| ___ Mesa (San Diego border crossing) | 36 |
| ___ Mesa | 8 |
| ___ meridiem (morning: Lat.) | 28 |
| ___ meridiem | 12 |
| ___ mercy (plead) | 17 |
| ___ mer | 7 |
| ___ Meow (Internet meme cat with extremely long fur) | 52 |
| ___ menu | 8 |
| ___ mention (besides) | 21 |
| ___ mentality | 13 |
| ___ Men, ''Who Let the Dogs Out'' group | 55 |
| ___ Men's Health Crisis | 27 |
| ___ Men with the 2000 hit "Who Let the Dogs Out" | 58 |
| ___ Men ("Who Let the Dogs Out?" group) | 49 |
| ___ Men ("Who Let the Dogs Out?" band) | 48 |
| ___ Men ("Who Let the Dogs Out" group) | 48 |
| ___ Men ("Who Let the Dogs Out" band) | 47 |
| ___ Men ("Move It Like This" group) | 45 |
| ___ melt (sandwich) | 19 |
| ___ melt | 8 |
| ___ Melodies | 12 |
| ___ mell | 8 |
| ___ Melba | 9 |
| ___ Meir Tower, Israel's first skyscraper | 45 |
| ___ Meir | 8 |
| ___ mein | 8 |
| ___ Meier, creator of the "Civilization" video game series | 68 |
| ___ Megiddo (city of ancient Palestine) | 39 |
| ___ Meeuwtje, Minuit's ship | 31 |
| ___ meeting | 11 |
| ___ meet (eke out) | 18 |
| ___ meet | 8 |
| ___ meeny miney mo | 18 |
| ___ mediocritas (golden mean) | 29 |
| ___ medicine (type of jurisprudence) | 36 |
| ___ medicine | 12 |
| ___ medical | 11 |
| ___ medica (physician's treatise) | 37 |
| ___ medica | 10 |
| ___ media (middle way) | 22 |
| ___ media (middle course) | 25 |
| ___ Med | 7 |
| ___ mecum (manual) | 18 |
| ___ mecum (handbook) | 20 |
| ___ mecum (guidebook) | 21 |
| ___ mecum | 9 |
| ___ meat | 8 |
| ___ measure | 11 |
| ___ means: certainly not | 24 |
| ___ means possible | 18 |
| ___ means (not at all) | 22 |
| ___ means (certainly) | 21 |
| ___ means (certainly not) | 25 |
| ___ means | 9 |
| ___ mean square (statistics calculation) | 40 |
| ___ meal (forego lunch) | 23 |
| ___ meal (cooks) | 16 |
| ___ Me! | 7 |
| ___ me tangere (touch-me-not) | 29 |
| ___ me tangere (something off-limits) | 37 |
| ___ me tangere (hands off!) | 27 |
| ___ me tangere (''touch me not'') | 49 |
| ___ me tangere | 14 |
| ___ me impune lacessit | 22 |
| ___ Me (Requiem Mass movement) | 30 |
| ___ me | 6 |
| ___ McNutt of comics | 20 |
| ___ McNally (atlas publisher) | 29 |
| ___ McMuffin | 12 |