| Disease for which riluzole received FDA approval in 1995 | 56 |
| Disease for which Pasteur created the first vaccine | 51 |
| Disease first spotted in the US in 2003 | 39 |
| Disease fighters | 16 |
| Disease fighter | 15 |
| Disease experts | 15 |
| Disease diagnosed by dentists | 29 |
| Disease contracted by Seal at an early age | 42 |
| Disease caused by vitamin B deficiency | 38 |
| Disease caused by strep | 23 |
| Disease caused by niacin and protein deficiency | 47 |
| Disease caused by lack of thiamine | 34 |
| Disease caused by herpesvirus, briefly | 38 |
| Disease caused by a thiamine deficiency | 39 |
| Disease cause | 13 |
| Disease caught from birds | 25 |
| Disease attacker | 16 |
| Disease associated with jerks: Abbr. | 36 |
| Disease also called pertussis | 29 |
| Disease also called hog cholera | 31 |
| Disease agent | 13 |
| Disease | 7 |
| Disdains | 8 |
| Disdaining one | 14 |
| Disdainful, pouting grimace | 27 |
| Disdainful upperclassman? | 25 |
| Disdainful sounds | 17 |
| Disdainful sound | 16 |
| Disdainful smile | 16 |
| Disdainful response | 19 |
| Disdainful remark | 17 |
| Disdainful rejections | 21 |
| Disdainful reactions | 20 |
| Disdainful one | 14 |
| Disdainful looks | 16 |
| Disdainful look | 15 |
| Disdainful interjection | 23 |
| Disdainful grimace | 18 |
| Disdainful glance | 17 |
| Disdainful expressions | 22 |
| Disdainful expression | 21 |
| Disdainful exclamation | 22 |
| Disdainful dismissals | 21 |
| Disdainful cry | 14 |
| Disdainful cries | 16 |
| Disdainful cluck | 16 |
| Disdainful bunch | 16 |
| Disdainful | 10 |
| Disdainer's noise | 21 |
| Disdained, with "at" | 30 |
| Disdained writer | 16 |
| Disdained newspaper | 19 |
| Disdained | 9 |
| Disdain, vocalized | 18 |
| Disdain for the unattainable | 28 |
| Disdain ... rank ... high-hat | 29 |
| Disdain | 7 |
| Discussions | 11 |
| Discussion-group member | 23 |
| Discussion-ending words | 23 |
| Discussion, for short | 21 |
| Discussion, briefly | 19 |
| Discussion with rocker Billy? | 29 |
| Discussion with one's therapist about a sparkly gold bath toy? | 66 |
| Discussion venues | 17 |
| Discussion venue | 16 |
| Discussion topic for feminists | 30 |
| Discussion subject | 18 |
| Discussion stopper | 18 |
| Discussion spots | 16 |
| Discussion spot | 15 |
| Discussion sites | 16 |
| Discussion site | 15 |
| Discussion query | 16 |
| Discussion point | 16 |
| Discussion place | 16 |
| Discussion opportunity | 22 |
| Discussion of facts | 19 |
| Discussion of both sides | 24 |
| Discussion of a Theocritus poem? | 32 |
| Discussion meetings | 19 |
| Discussion medium | 17 |
| Discussion groups | 17 |
| Discussion group, and a word that can follow the ends of this puzzle's five longest answers | 95 |
| Discussion group members | 24 |
| Discussion group choice | 23 |
| Discussion group | 16 |
| Discussion focus | 16 |
| Discussion ender | 16 |
| Discussion contribution | 23 |
| Discussion conclusion | 21 |
| Discussion between a former Colorado senator and a '70s-'90s rock band? | 79 |
| Discussion among netizens | 25 |
| Discussion addition | 19 |
| Discussion about which way to go? | 33 |
| Discussion | 10 |
| Discussing, with ''out'' | 40 |
| Discussing scores? | 18 |
| Discussing openly | 17 |
| Discussing excitedly | 20 |